Search Results - "GELPI, Ricardo J."
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Role of the parasympathetic nervous system in cardioprotection by remote hindlimb ischaemic preconditioning
Published in Experimental physiology (01-02-2013)“…New findings • What is the central question of this study? Ischaemia–reperfusion of peripheral tissues protects the heart from subsequent myocardial…”
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Mitochondrial bioenergetics links inflammation and cardiac contractility in endotoxemia
Published in Basic research in cardiology (01-09-2019)“…There is current awareness about the central role of mitochondrial dysfunction in the development of cardiac dysfunction in systemic inflammatory syndromes,…”
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Galectin-1 Controls Cardiac Inflammation and Ventricular Remodeling during Acute Myocardial Infarction
Published in The American journal of pathology (2013)“…Galectin-1 (Gal-1), an evolutionarily conserved β-galactoside-binding lectin, plays essential roles in the control of inflammation and neovascularization…”
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Galectin-3 is essential for early wound healing and ventricular remodeling after myocardial infarction in mice
Published in International journal of cardiology (20-10-2014)Get full text
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Subcellular distribution of ERK phosphorylation in tyrosine and threonine depends on redox status in murine lung cells
Published in PloS one (28-02-2018)“…Activation of ERK1/2 implies the phosphorylation of tyrosine (pTyr) and threonine (pThr) by MEK1/2; both reactions were thought to be cytoplasmic, promoting…”
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Myocardial triggers involved in activation of remote ischaemic preconditioning
Published in Experimental physiology (01-06-2016)“…New Findings What is the central question of this study? Ischaemia–reperfusion of peripheral tissues protects the heart from subsequent myocardial…”
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Cardiac Natriuretic Peptide Profiles in Chronic Hypertension by Single or Sequentially Combined Renovascular and DOCA-Salt Treatments
Published in Frontiers in physiology (25-05-2021)“…The involvement of natriuretic peptides was studied during the hypertrophic remodeling transition mediated by sequential exposure to chronic hemodynamic…”
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Changes in the loading conditions induced by vagal stimulation modify the myocardial infarct size through sympathetic-parasympathetic interactions
Published in Pflügers Archiv (01-07-2015)“…In a previous research, we described that vagal stimulation increases the infarct size by sympathetic co-activation. The aim of this study was to determine if…”
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Characterization of Tunneling Nanotubes in Wharton’s jelly Mesenchymal Stem Cells. An Intercellular Exchange of Components between Neighboring Cells
Published in Stem cell reviews (01-08-2017)“…Intercellular communication is one of the most important events in cell population behavior. In the last decade, tunneling nanotubes (TNTs) have been…”
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Pilocarpine-Induced Status Epilepticus Is Associated with P-Glycoprotein Induction in Cardiomyocytes, Electrocardiographic Changes, and Sudden Death
Published in Pharmaceuticals (Basel, Switzerland) (16-02-2018)“…Sudden unexpected death in epilepsy (SUDEP) is the major cause of death in those patients suffering from refractory epilepsy (RE), with a 24-fold higher risk…”
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Treatment with Fenofibrate plus a low dose of Benznidazole attenuates cardiac dysfunction in experimental Chagas disease
Published in International journal for parasitology -- drugs and drug resistance (01-12-2017)“…Trypanosoma cruzi induces serious cardiac alterations during the chronic infection. Intense inflammatory response observed from the beginning of infection, is…”
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Protecting the heart from ischemia/reperfusion injury: an update on remote ischemic preconditioning and postconditioning
Published in Current opinion in cardiology (01-11-2017)“…The most effective strategy for reducing acute myocardial ischemic injury is timely and effective reperfusion. However, myocardial reperfusion can induce…”
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Uma Nova Alternativa Terapêutica para o Tratamento da Hipertensão Pulmonar?
Published in Arquivos brasileiros de cardiologia (01-12-2021)Get full text
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A New Therapeutic Alternative for the Treatment of Pulmonary Hypertension?
Published in Arquivos brasileiros de cardiologia (01-12-2021)Get full text
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Role of matrix metalloproteinase-2 in the cardioprotective effect of ischaemic postconditioning
Published in Experimental physiology (01-02-2010)“…The activation of matrix metalloproteinases (MMPs) contributes to myocardial injury at the onset of reperfusion; however, their role in ischaemic…”
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Myocardial remote ischemic preconditioning: from cell biology to clinical application
Published in Molecular and cellular biochemistry (01-10-2021)“…Remote ischemic preconditioning (rIPC) is a cardioprotective phenomenon where brief periods of ischemia followed by reperfusion of one organ/tissue can confer…”
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Rosuvastatin Given During Reperfusion Decreases Infarct Size and Inhibits Matrix Metalloproteinase-2 Activity in Normocholesterolemic and Hypercholesterolemic Rabbits
Published in Journal of cardiovascular pharmacology (01-02-2009)“…There is evidence that statin treatment before ischemia protects myocardium from ischemia/reperfusion injury. The objective is to determine whether…”
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Remote ischemic preconditioning prevents sarcolemmal-associated proteolysis by MMP-2 inhibition
Published in Molecular and cellular biochemistry (01-09-2024)“…The death of myocytes occurs through different pathways, but the rupture of the plasma membrane is the key point in the transition from reversible to…”
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Cardiovagal activity confers cardioprotection after myocardial infarction: recent advances
Published in Experimental physiology (01-05-2016)Get full text
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Ventricular function and natriuretic peptides in sequentially combined models of hypertension
Published in American journal of physiology. Heart and circulatory physiology (01-04-2010)“…Hemodynamic parameters and natriuretic peptide levels were evaluated in cardiac hypertrophy produced by sequentially applied renovascular (RV) and…”
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