Search Results - "GELLER, N. L"

Diabetes clinical trials: helped or hindered by the current shift in regulatory requirements? by ZANNAD, Faiez, STOUGH, Wendy Gattis, ABADIE, Eric, ALONSO-GARCIA, Angeles, PITT, Bertram, POCOCK, Stuart J, SLEIGHT, Peter, CUSHMAN, William C, CLELAND, John G. F, MCMURRAY, John J. V, LONN, Eva, GELLER, Nancy L, WEDEL, Hans

“…Glycaemic control is an inadequate surrogate marker of cardiovascular event reduction in patients with type 2 diabetes. Clinical trials to date have been…”
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Effect of angiotensin converting enzyme inhibition on sudden cardiac death in patients following acute myocardial infarction : A meta-analysis of randomized clinical trials by DOMANSKI, M. J, EXNER, D. V, BORKOWF, C. B, GELLER, N. L, ROSENBERG, Y, PFEFFER, M. A

“…Estimate the effect of angiotensin converting enzyme (ACE) inhibitors on the risk of sudden cardiac death (SCD) following myocardial infarction (MI). Trials in…”
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Use of a global test for multiple outcomes in stroke trials with application to the national institute of neurological disorders and stroke t-PA stroke trial by TILLEY, B. C, MARLER, J, GELLER, N. L, LU, M, LEGLER, J, BROTT, T, LYDEN, P, GROTTA, J

“…The National Institute of Neurological Disorders and Stroke (NINDS) held a workshop on statistical approaches to analysis of acute stroke trials that have…”
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Randomized trial of etoposide and cisplatin versus etoposide and carboplatin in patients with good-risk germ cell tumors: a multiinstitutional study by Bajorin, D F, Sarosdy, M F, Pfister, D G, Mazumdar, M, Motzer, R J, Scher, H I, Geller, N L, Fair, W R, Herr, H, Sogani, P

“…This multicenter, randomized phase III clinical trial evaluated the efficacy of etoposide plus carboplatin (EC) versus etoposide plus cisplatin (EP) in…”
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The role of biostatistics in the prevention, detection and treatment of fraud in clinical trials by Buyse, Marc, George, Stephen L., Evans, Stephen, Geller, Nancy L., Ranstam, Jonas, Scherrer, Bruno, Lesaffre, Emmanuel, Murray, Gordon, Edler, Lutz, Hutton, Jane, Colton, Theodore, Lachenbruch, Peter, Verma, Babu L.

“…Recent cases of fraud in clinical trials have attracted considerable media attention, but relatively little reaction from the biostatistical community. In this…”
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Neurons in Monkey Prefrontal Cortex That Track Past or Predict Future Performance by Hasegawa, Ryohei P., Blitz, Ari M., Geller, Nancy L., Goldberg, Michael E.

“…Although frontal cortex is thought to be important in controlling behavior across long periods of time, most studies of this area concentrate on neuronal…”
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PHARMACEUTICAL SERVICES: STATUS AND DEVELOPMENT TRENDS by Klimenkova, A. A., Geller, L. N., Skripko, A. A., Gravchenko, L. A., Korzhavykh, E. A.

“…The aim of the review is to provide an analysis and generalization of the main directions of research in the sphere of pharmaceutical services, and their…”
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The Analysis of Multiple Endpoints in Clinical Trials by Pocock, Stuart J., Geller, Nancy L., Tsiatis, Anastasios A.

“…Treatment comparisons in randomized clinical trials usually involve several endpoints such that conventional significance testing can seriously inflate the…”
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On The Design and Analysis of Randomized Clinical Trials with Multiple Endpoints by Tang, Dei-In, Geller, Nancy L., Pocock, Stuart J.

“…This paper considers some methods for reducing the number of significance tests undertaken when analyzing and reporting results of clinical trials. Emphasis is…”
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QUALITY MANAGEMENT SYSTEM OF A PHARMACEUTICAL ORGANIZATION: CRITERIA AND IMPLEMENTATION by Klimenkova, A. A., Geller, L. N., Skripko, A. A., Gravchenko, L. A., Fedorenko, N. V.

“…The aim of the study is a theoretical justification and development of a mechanism for the implementation of quality management systems (QMS) in the activities…”
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MODELING PROCESS OF PALLIATIVE PHARMACEUTICAL CARE AS A COMPONENT OF PHARMACEUTICAL SAFETY AT THE LOCAL LEVEL by I. A. Tueva, L. N. Geller, A. L. Myimrina, L. A. Escheva, I. V. Vidyasova

“…The importance of the pharmaceutical safety of the palliative care system, good timing of its delivery, accessibility and quality have been actively discussed…”
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OPTIMIZATION OF PHARMACEUTICAL CARE FOR JUVENILE RHEUMATOID ARTHRITIS AT THE REGIONAL LEVEL by Skripko, A. A., Geller, L. N., Radnaev, G. G., Hadanova, Т. V.

“…Clinical practice and content analysis of scientifi c literature indicate that for treatment of the immune-infl amatory disease called juvenile rheumatoid…”
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Adjunctive surgery after chemotherapy for nonseminomatous germ cell tumors: recommendations for patient selection by Toner, G C, Panicek, D M, Heelan, R T, Geller, N L, Lin, S Y, Bajorin, D, Motzer, R J, Scher, H I, Herr, H W, Morse, M J

“…One hundred eighty-five patients who underwent surgery within 6 months of completing chemotherapy were identified from 360 patients with nonseminomatous germ…”
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Interim Analyses in Randomized Clinical Trials: Ramifications and Guidelines for Practitioners by Geller, Nancy L., Pocock, Stuart J.

“…Recent developments in group sequential methods have had a great impact on the design and analysis of randomized clinical trials. The consequences for both…”
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After a treatment breakthrough: a comparison of trial and population-based data for advanced testicular cancer by Feuer, E J, Frey, C M, Brawley, O W, Nayfield, S G, Cunningham, J B, Geller, N L, Bosl, G J, Kramer, B S

“…To determine to what extent the benefits of cisplatin-based combination chemotherapy have been disseminated to all American men diagnosed with advanced…”
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VAB-6: an effective chemotherapy regimen for patients with germ-cell tumors by Bosl, G J, Gluckman, R, Geller, N L, Golbey, R B, Whitmore, Jr, W F, Herr, H, Sogani, P, Morse, M, Martini, N, Bains, M

“…One hundred sixty-six patients with germ-cell tumors (GCT) of the testis, retroperitoneum, and mediastinum were treated with cyclophosphamide, vinblastine,…”
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INSTITUTE OF MEDICAL REPRESENTATIONS: PROBLEMS AND SOLUTIONS by Skripko, A. A., Fyodorova, N. V., Dorofeeva, V. V., Geller, L. N.

“…A growing potential of Russian pharmaceutical market and constant medicinal drugs range widening requires a necessity to search for more effective ways of…”
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Effect of relative cumulative dose-intensity on survival of patients with urothelial cancer treated with M-VAC by Scher, H I, Geller, N L, Curley, T, Tao, Y

“…To evaluate the received dose-intensity in a mature data set of patients with advanced urothelial cancer who received at least one cycle of the methotrexate…”
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Monitoring Pairwise Comparisons in Multi-Armed Clinical Trials by Follmann, Dean A., Proschan, Michael A., Geller, Nancy L.

“…This paper proposes a method for monitoring multi-armed clinical trials on the basis of pairwise comparisons between arms. The set of pairwise test statistics…”
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A prospective randomized comparison of epirubicin and doxorubicin in patients with advanced breast cancer by Jain, K K, Casper, E S, Geller, N L, Hakes, T B, Kaufman, R J, Currie, V, Schwartz, W, Cassidy, C, Petroni, G R, Young, C W

“…Fifty-four patients with advanced breast cancer who had failed prior non-anthracycline combination chemotherapy were randomized to treatment with either…”
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