Search Results - "GELAO, Barbara"
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Emotion-body connection dispositions modify the insulae-midcingulate effective connectivity during anger processing
Published in PloS one (13-02-2020)“…The link between anger and bodily states is readily apparent based on the autonomic and behavioral responses elicited. In everyday life angry people react in…”
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The genetic architecture of human brainstem structures and their involvement in common brain disorders
Published in Nature communications (11-08-2020)“…Brainstem regions support vital bodily functions, yet their genetic architectures and involvement in common brain disorders remain understudied. Here, using…”
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FXR1P is a GSK3β substrate regulating mood and emotion processing
Published in Proceedings of the National Academy of Sciences - PNAS (18-08-2015)“…Inhibition of glycogen synthase kinase 3β (GSK3β) is a shared action believed to be involved in the regulation of behavior by psychoactive drugs such as…”
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How to improve the physical health of people with severe mental illness? A multicentric randomized controlled trial on the efficacy of a lifestyle group intervention
Published in European psychiatry (23-11-2021)“…People with severe mental illnesses (SMI) have a mortality rate two times higher compared to the general population, with a decade of years of life lost. In…”
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Evidence of an interaction between FXR1 and GSK3β polymorphisms on levels of Negative Symptoms of Schizophrenia and their response to antipsychotics
Published in European psychiatry (19-04-2021)“…Genome-Wide Association Studies (GWASs) have identified several genes associated with Schizophrenia (SCZ) and exponentially increased knowledge on the genetic…”
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Rasd2 Modulates Prefronto-Striatal Phenotypes in Humans and 'Schizophrenia-Like Behaviors' in Mice
Published in Neuropsychopharmacology (New York, N.Y.) (01-02-2016)“…Rasd2 is a thyroid hormone target gene, which encodes for a GTP-binding protein enriched in the striatum where, among other functions, it modulates…”
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DRD2/AKT1 interaction on D2 c-AMP independent signaling, attentional processing, and response to olanzapine treatment in schizophrenia
Published in Proceedings of the National Academy of Sciences - PNAS (18-01-2011)“…The D2/AKT1/GSK-3β signaling pathway has been involved in the downstream intracellular effects of dopamine, in the pathophysiology of cognitive deficits and…”
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Prefrontal Activity and Connectivity with the Basal Ganglia during Performance of Complex Cognitive Tasks Is Associated with Apathy in Healthy Subjects
Published in PloS one (31-10-2016)“…Convergent evidence indicates that apathy affects cognitive behavior in different neurological and psychiatric conditions. Studies of clinical populations have…”
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Machine learning-based ability to classify psychosis and early stages of disease through parenting and attachment-related variables is associated with social cognition
Published in BMC Psychology (23-03-2021)“…Recent views posited that negative parenting and attachment insecurity can be considered as general environmental factors of vulnerability for psychosis,…”
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BDNF rs6265 methylation and genotype interact on risk for schizophrenia
Published in Epigenetics (02-01-2016)“…Epigenetic mechanisms can mediate gene-environment interactions relevant for complex disorders. The BDNF gene is crucial for development and brain plasticity,…”
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Genetically determined measures of striatal D2 signaling predict prefrontal activity during working memory performance
Published in PloS one (22-02-2010)“…Variation of the gene coding for D2 receptors (DRD2) has been associated with risk for schizophrenia and with working memory deficits. A functional intronic…”
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DRD2/CHRNA5 interaction on prefrontal biology and physiology during working memory
Published in PloS one (12-05-2014)“…Prefrontal behavior and activity in humans are heritable. Studies in animals demonstrate an interaction between dopamine D2 receptors and nicotinic…”
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Expression of DISC1-interactome members correlates with cognitive phenotypes related to schizophrenia
Published in PloS one (18-06-2014)“…Cognitive dysfunction is central to the schizophrenia phenotype. Genetic and functional studies have implicated Disrupted-in-Schizophrenia 1 (DISC1), a leading…”
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Interplay Among Psychopathologic Variables, Personal Resources, Context-Related Factors, and Real-life Functioning in Individuals With Schizophrenia: A Network Analysis
Published in JAMA psychiatry (Chicago, Ill.) (01-04-2018)“…Enhanced understanding of factors associated with symptomatic and functional recovery is instrumental to designing personalized treatment plans for people with…”
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A Pattern of Cognitive Deficits Stratified for Genetic and Environmental Risk Reliably Classifies Patients With Schizophrenia From Healthy Control Subjects
Published in Biological psychiatry (1969) (15-04-2020)“…Schizophrenia risk is associated with both genetic and environmental risk factors. Furthermore, cognitive abnormalities are established core characteristics of…”
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Genetic Variation of a DRD2 Co-expression Network is Associated with Changes in Prefrontal Function After D2 Receptors Stimulation
Published in Cerebral cortex (New York, N.Y. 1991) (01-03-2019)“…Abstract Dopamine D2 receptors (D2Rs) contribute to the inverted U-shaped relationship between dopamine signaling and prefrontal function. Genetic networks…”
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Transcriptomic context of DRD1 is associated with prefrontal activity and behavior during working memory
Published in Proceedings of the National Academy of Sciences - PNAS (22-05-2018)“…Dopamine D₁ receptor (D₁R) signaling shapes prefrontal cortex (PFC) activity during working memory (WM). Previous reports found higher WM performance…”
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Subcortical Gray Matter Volume is Associated With Schizophrenia and With Both its Familial and Clinical Risk
Published in Biological psychiatry (1969) (01-05-2020)Get full text
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Evocative gene‐environment correlation between genetic risk for schizophrenia and bullying victimization
Published in World psychiatry (01-10-2019)Get full text
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Treatment with Olanzapine is Associated with Modulation of the Default Mode Network in Patients with Schizophrenia
Published in Neuropsychopharmacology (New York, N.Y.) (01-03-2010)“…Earlier studies have shown widespread alterations of functional connectivity of various brain networks in schizophrenia, including the default mode network…”
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