Search Results - "GEJYO, F"

Etiology and prognostic significance of severe uremic pruritus in chronic hemodialysis patients by Narita, I., Alchi, B., Omori, K., Sato, F., Ajiro, J., Saga, D., Kondo, D., Skatsume, M., Maruyama, S., Kazama, J.J., Akazawa, K., Gejyo, F.

“…Although uremia is well known as the most common cause of pruritus, the mechanisms of pruritus in chronic hemodialysis patients remain unclear. The purpose was…”
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Efficacy of colistin combination therapy in a mouse model of pneumonia caused by multidrug-resistant Pseudomonas aeruginosa by Aoki, Nobumasa, Tateda, Kazuhiro, Kikuchi, Yoshiaki, Kimura, Soichiro, Miyazaki, Choichiroh, Ishii, Yoshikazu, Tanabe, Yoshinari, Gejyo, Fumitake, Yamaguchi, Keizo

“…Objectives Multidrug-resistant Pseudomonas aeruginosa (MDRP) is becoming a serious problem in hospitals, especially in patients on ventilators. Recent data…”
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Expression, roles, receptors, and regulation of osteopontin in the kidney by Xie, Yuansheng, Sakatsume, Minoru, Nishi, Shinichi, Narita, Ichiei, Arakawa, Masaaki, Gejyo, Fumitake

“…Expression, roles, receptors, and regulation of osteopontin in the kidney. Osteopontin (OPN) is a secreted glycoprotein in both phosphorylated and…”
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Effects of edaravone, a free-radical scavenger, on bleomycin-induced lung injury in mice by Tajima, S, Bando, M, Ishii, Y, Hosono, T, Yamasawa, H, Ohno, S, Takada, T, Suzuki, E, Gejyo, F, Sugiyama, Y

“…Reactive oxygen species play an important role in the pathogenesis of acute lung injury and pulmonary fibrosis. The present authors hypothesise that edaravone,…”
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High-level expression of naked DNA delivered to rat liver via tail vein injection by Maruyama, H., Higuchi, N., Nishikawa, Y., Kameda, S., Iino, N., Kazama, J. J., Takahashi, N., Sugawa, M., Hanawa, H., Tada, N., Miyazaki, J., Gejyo, F.

“…Background High levels of foreign gene expression in mouse hepatocytes can be achieved by rapid tail vein injection of a large volume of a naked DNA solution,…”
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Expression of allograft inflammatory factor-1 in kidneys: A novel molecular component of podocyte by Tsubata, Y., Sakatsume, M., Ogawa, A., Alchi, B., Kaneko, Y., Kuroda, T., Kawachi, H., Narita, I., Yamamoto, T., Gejyo, F.

“…Our comprehensive gene expression profiles of the kidneys in an anti-glomerular basement membrane (GBM) nephritis model using DNA arrays revealed that…”
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Patients undergoing dialysis therapy for 30 years or more survive with serious osteoarticular disorders by Yamamoto, S, Kazama, J J, Maruyama, H, Nishi, S, Narita, I, Gejyo, F

“…Increasing numbers of patients are undergoing long-term dialysis therapy. It is crucial for their quality of life to overcome dialysis-related complications,…”
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A prostacyclin agonist with thromboxane inhibitory activity for airway allergic inflammation in mice by Hayashi, M., Koya, T., Kawakami, H., Sakagami, T., Hasegawa, T., Kagamu, H., Takada, T., Sakai, Y., Suzuki, E., Gelfand, E. W., Gejyo, F.

“…Summary Background ONO‐1301 is a novel drug that acts as a prostacyclin agonist with thromboxane A2 (TxA2) synthase inhibitory activity. We investigated the…”
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Skin-targeted gene transfer using in vivo electroporation by MARUYAMA, H, ATAKA, K, HIGUCHI, N, SAKAMOTO, F, GEJYO, F, MIYAZAKI, J

“…The skin is an important target for gene transfer because of its easy accessibility. Using plasmid DNA expressing rat erythropoietin (pCAGGS-Epo) as the…”
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Cystatin C is a sensitive marker for detecting a reduced glomerular filtration rate when assessing chronic kidney disease in patients with rheumatoid arthritis and secondary amyloidosis by Sato, H, Kuroda, T, Tanabe, N, Ajiro, J, Wada, Y, Murakami, S, Sakatsume, M, Nakano, M, Gejyo, F

“…Objective: Chronic kidney disease is a predictor of end-stage renal disease, and evaluating the glomerular filtration rate (GFR) is necessary to make a…”
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Paraneoplastic neurological syndrome and polyglandular autoimmune syndrome type 2 in a case of small cell lung cancer by Watanabe, S, Tanaka, J, Ohta, T, Yoshizawa, H, Gejyo, F

“…We report a female patient with small cell lung cancer (SCLC) and clinical findings consistent with polyglandular autoimmune syndrome type 2 (PGA2) and…”
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Turbulence of glomerular hemodynamics involved in progressive glomerulosclerosis by Kawamura, K., Okada, S., Li, B., Suwa, M., Yao, J., Morioka, T., Gejyo, F., Oite, T.

“…There is increasing evidence that changes of glomerular hemodynamics or glomerular growth responses may promote the development of glomerulosclerosis. Major…”
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Appropriate Timing of CD40 Ligation for RNA-Pulsed DCs to Induce Antitumor Immunity by Miura, S, Kagamu, H, Tanaka, H, Yoshizawa, H, Gejyo, F

“…Dendritic cell (DC) based anti-cancer immunotherapy is believed to be a promising treatment. However, appropriate conditioning including the method of antigen…”
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The genetic susceptibility to IgA nephropathy: A novel functional candidate gene for incomplete O-glycosylation of IgA1 by Narita, I., Kaneko, Y., Kondo, D., Goto, S., Sakatsume, M., Gejyo, F.

“…Incompleteness of O-glycosylation in the IgA1 hinge has been implicated as a central mechanism in the development of IgA nephropathy. Although…”
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Contribution of aspirin-intolerant asthma to near fatal asthma based on a questionnaire survey in Niigata Prefecture, Japan by YOSHIMINE, Fumitoshi, HASEGAWA, Takashi, SUZUKI, Eiichi, TERADA, Masaki, KOYA, Toshiyuki, KONDOH, Ariyoshi, ARAKAWA, Masaaki, YOSHIZAWA, Hirohisa, GEJYO, Fumitake

“…Objective:  Prevention of deaths due to asthma is one of the most important issues in asthma management. However, there are few epidemiological studies of…”
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Long-term production of erythropoietin after electroporation-mediated transfer of plasmid DNA into the muscles of normal and uremic rats by MARUYAMA, H, ATAKA, K, KIKUCHI, H, SUGAWA, M, MIYAZAKI, J, GEJYO, F, HIGUCHI, N, ITO, Y, HIRAHARA, H, IMAZEKI, I, HIRATA, M, ICHIKAWA, F, NEICHI, T

“…The anemia associated with chronic renal failure is one of the best target diseases for erythropoietin (Epo) gene transfer. We previously reported a short-term…”
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Comparison of gastroduodenal, renal and abdominal fat biopsies for diagnosing amyloidosis in rheumatoid arthritis by Kuroda, T, Tanabe, N, Sakatsume, M, Nozawa, S, Mitsuka, T, Ishikawa, H, Tohyama, C T, Nakazono, K, Murasawa, A, Nakano, M, Gejyo, F

“…The aim of the study was to determine the frequency of amyloidosis detected by gastroduodenal biopsy in rheumatoid arthritis (RA) patients, and to investigate…”
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Clinical and pathogenic factors in dialysis-related amyloidosis: current research findings by Gejyo, F

“…Dialysis-related amyloidosis is a serious complication in patients who are receiving long-term dialysis. It is important to determine the mechanism of its…”
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Kidney-targeted naked DNA transfer by retrograde injection into the renal vein in mice by Kameda, S, Maruyama, H, Higuchi, N, Iino, N, Nakamura, G, Miyazaki, J, Gejyo, F

“…We recently developed a novel kidney-targeted gene transfer technique in rats, using the retrograde renal vein injection of naked plasmid DNA. Many animal…”
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Hydrodynamics-based delivery of the viral interleukin-10 gene suppresses experimental crescentic glomerulonephritis in Wistar-Kyoto rats by HIGUCHI, N, MARUYAMA, H, GEJYO, F, KURODA, T, KAMEDA, S, IINO, N, KAWACHI, H, NISHIKAWA, Y, HANAWA, H, TAHARA, H, MIYAZAKI, J

“…Gene therapy is expected to revolutionize the treatment of kidney diseases. Viral interleukin (vIL)-10 has a variety of immunomodulatory properties. We…”
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