Search Results - "GEISBERT, Joan B"

Establishment of an African green monkey model for COVID-19 and protection against re-infection by Woolsey, Courtney, Borisevich, Viktoriya, Prasad, Abhishek N., Agans, Krystle N., Deer, Daniel J., Dobias, Natalie S., Heymann, John C., Foster, Stephanie L., Levine, Corri B., Medina, Liana, Melody, Kevin, Geisbert, Joan B., Fenton, Karla A., Geisbert, Thomas W., Cross, Robert W.

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for an unprecedented global pandemic of COVID-19. Animal models are urgently needed…”
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Lipid nanoparticle siRNA treatment of Ebola-virus-Makona-infected nonhuman primates by Thi, Emily P., Mire, Chad E., Lee, Amy C. H., Geisbert, Joan B., Zhou, Joy Z., Agans, Krystle N., Snead, Nicholas M., Deer, Daniel J., Barnard, Trisha R., Fenton, Karla A., MacLachlan, Ian, Geisbert, Thomas W.

“…Ebola-virus-targeting short interfering RNAs (siRNAs) encapsulated in lipid nanoparticles are adapted to the current outbreak strain of the virus, and the…”
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Human-monoclonal-antibody therapy protects nonhuman primates against advanced Lassa fever by Mire, Chad E, Cross, Robert W, Geisbert, Joan B, Borisevich, Viktoriya, Agans, Krystle N, Deer, Daniel J, Heinrich, Megan L, Rowland, Megan M, Goba, Augustine, Momoh, Mambu, Boisen, Mathew L, Grant, Donald S, Fullah, Mohamed, Khan, Sheik Humarr, Fenton, Karla A, Robinson, James E, Branco, Luis M, Garry, Robert F, Geisbert, Thomas W

“…Thomas Geisbert and colleagues show that a cocktail of monoclonal antibodies protects cynomolgus monkeys from lethal Lassa fever virus infection, including…”
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Intranasal exposure of African green monkeys to SARS-CoV-2 results in acute phase pneumonia with shedding and lung injury still present in the early convalescence phase by Cross, Robert W, Agans, Krystle N, Prasad, Abhishek N, Borisevich, Viktoriya, Woolsey, Courtney, Deer, Daniel J, Dobias, Natalie S, Geisbert, Joan B, Fenton, Karla A, Geisbert, Thomas W

“…We recently reported the development of the first African green monkey (AGM) model for COVID-19 based on a combined liquid intranasal (i.n.) and intratracheal…”
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Recombinant vesicular stomatitis virus-vectored vaccine induces long-lasting immunity against Nipah virus disease by Woolsey, Courtney, Borisevich, Viktoriya, Fears, Alyssa C, Agans, Krystle N, Deer, Daniel J, Prasad, Abhishek N, O'Toole, Rachel, Foster, Stephanie L, Dobias, Natalie S, Geisbert, Joan B, Fenton, Karla A, Cross, Robert W, Geisbert, Thomas W

“…The emergence of the novel henipavirus, Langya virus, received global attention after the virus sickened over three dozen people in China. There is heightened…”
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Combination therapy protects macaques against advanced Marburg virus disease by Cross, Robert W., Bornholdt, Zachary A., Prasad, Abhishek N., Borisevich, Viktoriya, Agans, Krystle N., Deer, Daniel J., Abelson, Dafna M., Kim, Do H., Shestowsky, William S., Campbell, Lioudmila A., Bunyan, Elaine, Geisbert, Joan B., Fenton, Karla A., Zeitlin, Larry, Porter, Danielle P., Geisbert, Thomas W.

“…Monoclonal antibodies (mAbs) and remdesivir, a small-molecule antiviral, are promising monotherapies for many viruses, including members of the genera…”
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Use of Single-Injection Recombinant Vesicular Stomatitis Virus Vaccine to Protect Nonhuman Primates Against Lethal Nipah Virus Disease by Mire, Chad E, Geisbert, Joan B, Agans, Krystle N, Versteeg, Krista M, Deer, Daniel J, Satterfield, Benjamin A, Fenton, Karla A, Geisbert, Thomas W

“…Nipah virus (NiV) is a zoonotic pathogen that causes high case-fatality rates (CFRs) in humans. Two NiV strains have caused outbreaks: the Malaysia strain (NiV…”
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Single-Injection Vaccine Protects Nonhuman Primates against Infection with Marburg Virus and Three Species of Ebola Virus by GEISBERT, Thomas W, GEISBERT, Joan B, LEUNG, Anders, DADDARIO-DICAPRIO, Kathleen M, HENSLEY, Lisa E, GROLLA, Allen, FELDMANN, Heinz

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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A highly attenuated Vesiculovax vaccine rapidly protects nonhuman primates against lethal Marburg virus challenge by Woolsey, Courtney, Cross, Robert W, Agans, Krystle N, Borisevich, Viktoriya, Deer, Daniel J, Geisbert, Joan B, Gerardi, Cheryl, Latham, Theresa E, Fenton, Karla A, Egan, Michael A, Eldridge, John H, Geisbert, Thomas W, Matassov, Demetrius

“…Marburg virus (MARV), an Ebola-like virus, remains an eminent threat to public health as demonstrated by its high associated mortality rate (23-90%) and recent…”
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Effective post-exposure treatment of Ebola infection by Feldmann, Heinz, Jones, Steven M, Daddario-DiCaprio, Kathleen M, Geisbert, Joan B, Ströher, Ute, Grolla, Allen, Bray, Mike, Fritz, Elizabeth A, Fernando, Lisa, Feldmann, Friederike, Hensley, Lisa E, Geisbert, Thomas W

“…Ebola viruses are highly lethal human pathogens that have received considerable attention in recent years due to an increasing re-emergence in Central Africa…”
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Use of convalescent serum reduces severity of COVID-19 in nonhuman primates by Cross, Robert W., Prasad, Abhishek N., Borisevich, Viktoriya, Woolsey, Courtney, Agans, Krystle N., Deer, Daniel J., Dobias, Natalie S., Geisbert, Joan B., Fenton, Karla A., Geisbert, Thomas W.

“…Passive transfer of convalescent plasma or serum is a time-honored strategy for treating infectious diseases. Human convalescent plasma containing antibodies…”
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Development of an acute and highly pathogenic nonhuman primate model of Nipah virus infection by Geisbert, Thomas W, Daddario-DiCaprio, Kathleen M, Hickey, Andrew C, Smith, Mark A, Chan, Yee-Peng, Wang, Lin-Fa, Mattapallil, Joseph J, Geisbert, Joan B, Bossart, Katharine N, Broder, Christopher C

“…Nipah virus (NiV) is an enigmatic emerging pathogen that causes severe and often fatal neurologic and/or respiratory disease in both animals and humans…”
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Natural history of nonhuman primates after conjunctival exposure to Ebola virus by Cross, Robert W., Prasad, Abhishek N., Woolsey, Courtney B., Agans, Krystle N., Borisevich, Viktoriya, Dobias, Natalie S., Comer, Jason E., Deer, Daniel J., Geisbert, Joan B., Rasmussen, Angela L., Lipkin, Walter Ian, Fenton, Karla A., Geisbert, Thomas W.

“…Transmission of Ebola virus (EBOV) primarily occurs via contact exposure of mucosal surfaces with infected body fluids. Historically, nonhuman primate (NHP)…”
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Prior vaccination with rVSV-ZEBOV does not interfere with but improves efficacy of postexposure antibody treatment by Cross, Robert W., Bornholdt, Zachary A., Prasad, Abhishek N., Geisbert, Joan B., Borisevich, Viktoriya, Agans, Krystle N., Deer, Daniel J., Melody, Kevin, Fenton, Karla A., Feldmann, Heinz, Sprecher, Armand, Zeitlin, Larry, Geisbert, Thomas W.

“…A replication-competent vesicular stomatitis virus vaccine expressing the Ebola virus (EBOV) glycoprotein (GP) (rVSV-ZEBOV) was successfully used during the…”
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Passive Immunotherapy: Assessment of Convalescent Serum Against Ebola Virus Makona Infection in Nonhuman Primates by Mire, Chad E., Geisbert, Joan B., Agans, Krystle N., Thi, Emily P., Lee, Amy C. H., Fenton, Karla A., Geisbert, Thomas W.

“…Background. Convalescent serum and blood were used to treat patients during outbreaks of Zaire ebolavirus (ZEBOV) infection in 1976 and 1995, with inconclusive…”
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Recombinant Protein Filovirus Vaccines Protect Cynomolgus Macaques From Ebola, Sudan, and Marburg Viruses by Lehrer, Axel T, Chuang, Eleanore, Namekar, Madhuri, Williams, Caitlin A, Wong, Teri Ann S, Lieberman, Michael M, Granados, Alex, Misamore, John, Yalley-Ogunro, Jake, Andersen, Hanne, Geisbert, Joan B, Agans, Krystle N, Cross, Robert W, Geisbert, Thomas W

“…Ebola (EBOV), Marburg (MARV) and Sudan (SUDV) viruses are the three filoviruses which have caused the most fatalities in humans. Transmission from animals into…”
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Vesicular stomatitis virus-based vaccines protect nonhuman primates against Bundibugyo ebolavirus by Mire, Chad E, Geisbert, Joan B, Marzi, Andrea, Agans, Krystle N, Feldmann, Heinz, Geisbert, Thomas W

“…Ebola virus (EBOV) causes severe and often fatal hemorrhagic fever in humans and nonhuman primates (NHPs). Currently, there are no licensed vaccines or…”
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Vesicular stomatitis virus-based ebola vaccine is well-tolerated and protects immunocompromised nonhuman primates by Geisbert, Thomas W, Daddario-Dicaprio, Kathleen M, Lewis, Mark G, Geisbert, Joan B, Grolla, Allen, Leung, Anders, Paragas, Jason, Matthias, Lennox, Smith, Mark A, Jones, Steven M, Hensley, Lisa E, Feldmann, Heinz, Jahrling, Peter B

“…Ebola virus (EBOV) is a significant human pathogen that presents a public health concern as an emerging/re-emerging virus and as a potential biological weapon…”
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Oral and Conjunctival Exposure of Nonhuman Primates to Low Doses of Ebola Makona Virus by Mire, Chad E., Geisbert, Joan B., Agans, Krystle N., Deer, Daniel J., Fenton, Karla A., Geisbert, Thomas W.

“…Nonhuman primate (NHP) models of Ebola virus (EBOV) infection primarily use parenteral or aerosol routes of exposure. Uniform lethality can be achieved in…”
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Durability of a vesicular stomatitis virus-based marburg virus vaccine in nonhuman primates by Mire, Chad E, Geisbert, Joan B, Agans, Krystle N, Satterfield, Benjamin A, Versteeg, Krista M, Fritz, Elizabeth A, Feldmann, Heinz, Hensley, Lisa E, Geisbert, Thomas W

“…The filoviruses, Marburg virus (MARV) and Ebola virus, causes severe hemorrhagic fever with high mortality in humans and nonhuman primates. A promising…”
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