Search Results - "GEIGER, Helmut"

Adipose-Derived Mesenchymal Stromal/Stem Cells: Tissue Localization, Characterization, and Heterogeneity by Baer, Patrick C., Geiger, Helmut

“…Adipose tissue as a stem cell source is ubiquitously available and has several advantages compared to other sources. It is easily accessible in large…”
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Kidney Inflammation, Injury and Regeneration 2020 by Baer, Patrick C., Koch, Benjamin, Geiger, Helmut

“…The kidneys play a vital role in the basic physiological functions of the body [...]…”
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Kidney Inflammation, Injury and Regeneration by Baer, Patrick C, Koch, Benjamin, Geiger, Helmut

“…Damage to kidney cells can occur due to a variety of ischemic and toxic insults and leads to inflammation and cell death, which can result in acute kidney…”
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Transcriptomics of Marburg virus-infected primary proximal tubular cells reveals negative correlation of immune response and energy metabolism by Koch, Benjamin, Filzmayer, Maximilian, Patyna, Sammy, Wetzstein, Nils, Lampe, Sebastian, Schmid, Tobias, Geiger, Helmut, Baer, Patrick C., Dolnik, Olga

“…•Marburg virus infects and replicates in primary human proximal tubular cells (PTC).•Transcriptome analyses at multiple time points revealed a profound…”
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Native T1 and T2 provide distinctive signatures in hypertrophic cardiac conditions – Comparison of uremic, hypertensive and hypertrophic cardiomyopathy by Arcari, Luca, Hinojar, Rocio, Engel, Juergen, Freiwald, Tilo, Platschek, Steffen, Zainal, Hafisyatul, Zhou, Hui, Vasquez, Moises, Keller, Till, Rolf, Andreas, Geiger, Helmut, Hauser, Ingeborg, Vogl, Thomas J., Zeiher, Andreas M., Volpe, Massimo, Nagel, Eike, Puntmann, Valentina O.

“…Profound left ventricular (LV) hypertrophy with diastolic dysfunction and heart failure is the cardinal manifestation of heart remodelling in chronic kidney…”
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Gliflozins Have an Anti-Inflammatory Effect on Renal Proximal Tubular Epithelial Cells in a Diabetic and Inflammatory Microenvironment In Vitro by Koch, Benjamin, Fuhrmann, Dominik C, Schubert, Ralf, Geiger, Helmut, Speer, Thimoteus, Baer, Patrick C

“…Inflammation is intimately involved in the pathogenesis of diabetic kidney disease. Inhibition of SGLT-2 by a specific class of drugs, gliflozins, has been…”
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No Cytotoxic and Inflammatory Effects of Empagliflozin and Dapagliflozin on Primary Renal Proximal Tubular Epithelial Cells under Diabetic Conditions In Vitro by Baer, Patrick C, Koch, Benjamin, Freitag, Janina, Schubert, Ralf, Geiger, Helmut

“…Gliflozins are inhibitors of the renal proximal tubular sodium-glucose co-transporter-2 (SGLT-2), that inhibit reabsorption of urinary glucose and they are…”
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Cardiac biomarkers in chronic kidney disease are independently associated with myocardial edema and diffuse fibrosis by cardiovascular magnetic resonance by Arcari, Luca, Engel, Juergen, Freiwald, Tilo, Zhou, Hui, Zainal, Hafisyatul, Gawor, Monika, Buettner, Stefan, Geiger, Helmut, Hauser, Ingeborg, Nagel, Eike, Puntmann, Valentina O

“…High sensitivity cardiac troponin T (hs-cTnT) and NT-pro-brain natriuretic peptide (NT-pro BNP) are often elevated in chronic kidney disease (CKD) and…”
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Tracking of Adipose-Derived Mesenchymal Stromal/Stem Cells in a Model of Cisplatin-Induced Acute Kidney Injury: Comparison of Bioluminescence Imaging versus qRT-PCR by Schubert, Ralf, Sann, Julia, Frueh, Jochen T, Ullrich, Evelyn, Geiger, Helmut, Baer, Patrick C

“…Determining the cell fate and the distribution of mesenchymal stromal/stem cells (MSCs) after transplantation are essential parts of characterizing the…”
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Epithelial differentiation of human adipose tissue-derived adult stem cells by Brzoska, Martin, Geiger, Helmut, Gauer, Stefan, Baer, Patrick

“…Adult human stem cells are employed in novel treatments and bio-artificial devices. Recent studies have identified an abundant source of stem cells termed…”
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Characterization of Extracellular Vesicles from Preconditioned Human Adipose-Derived Stromal/Stem Cells by Geßner, Alec, Koch, Benjamin, Klann, Kevin, Fuhrmann, Dominik C, Farmand, Samira, Schubert, Ralf, Münch, Christian, Geiger, Helmut, Baer, Patrick C

“…Cell-free therapy using extracellular vesicles (EVs) from adipose-derived mesenchymal stromal/stem cells (ASCs) seems to be a safe and effective therapeutic…”
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Resistant hypertension? Assessment of adherence by toxicological urine analysis by Jung, Oliver, Gechter, Janis L., Wunder, Cora, Paulke, Alexander, Bartel, Christine, Geiger, Helmut, Toennes, Stefan W.

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Influenza A virus replicates productively in primary human kidney cells and induces factors and mechanisms related to regulated cell death and renal pathology observed in virus-infected patients by Koch, Benjamin, Shehata, Mahmoud, Müller-Ruttloff, Christin, Gouda, Shady A, Wetzstein, Nils, Patyna, Sammy, Scholz, Anica, Schmid, Tobias, Dietrich, Ursula, Münch, Christian, Ziebuhr, John, Geiger, Helmut, Martinez-Sobrido, Luis, Baer, Patrick C, Mostafa, Ahmed, Pleschka, Stephan

“…Influenza A virus (IAV) infection can cause the often-lethal acute respiratory distress syndrome (ARDS) of the lung. Concomitantly, acute kidney injury (AKI)…”
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Effect of Different Preconditioning Regimens on the Expression Profile of Murine Adipose-Derived Stromal/Stem Cells by Baer, Patrick C, Overath, Jürgen M, Urbschat, Anja, Schubert, Ralf, Koch, Benjamin, Bohn, Asanke A, Geiger, Helmut

“…Stem cell-based therapies require cells with a maximum regenerative capacity in order to support regeneration after tissue injury and organ failure…”
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Direct acute tubular damage contributes to Shigatoxin-mediated kidney failure by Porubsky, Stefan, Federico, Giuseppina, Müthing, Johannes, Jennemann, Richard, Gretz, Norbert, Büttner, Stefan, Obermüller, Nicholas, Jung, Oliver, Hauser, Ingeborg A, Gröne, Elisabeth, Geiger, Helmut, Gröne, Hermann-Josef, Betz, Christoph

“…The pathogenesis and therapy of Shigatoxin 2 (Stx2)‐mediated kidney failure remain controversial. Our aim was to test whether, during an infection with…”
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Acute kidney injury after in-hospital cardiac arrest in a predominant internal medicine and cardiology patient population: incidence, risk factors, and impact on survival by Patyna, Sammy, Riekert, Kirsten, Buettner, Stefan, Wagner, Anna, Volk, Johannes, Weiler, Helge, Erath-Honold, Julia W., Geiger, Helmut, Fichtlscherer, Stephan, Honold, Jörg

“…Prognosis of survivors from cardiac arrest is generally poor. Acute kidney injury (AKI) is a common finding in these patients. In general, AKI is well…”
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Isolation, Characterization, Differentiation and Immunomodulatory Capacity of Mesenchymal Stromal/Stem Cells from Human Perirenal Adipose Tissue by Baer, Patrick C, Koch, Benjamin, Hickmann, Elena, Schubert, Ralf, Cinatl, Jr, Jindrich, Hauser, Ingeborg A, Geiger, Helmut

“…Mesenchymal stromal/stem cells (MSCs) are immature multipotent cells, which represent a rare population in the perivascular niche within nearly all tissues…”
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Risk of graft loss in kidney transplant recipients after aortic valve replacement by Büttner, Stefan, Zöller, Carolin, Patyna, Sammy, Gradascevic, Anisa, Weiler, Helge, Rosenberg, Mark, Walther, Thomas, Zeiher, Andreas M, Geiger, Helmut, Vasa-Nicotera, Mariuca, Hauser, Ingeborg, Fichtlscherer, Stephan

“…Surgical aortic valve replacement (SAVR) in kidney transplant recipients (KTR) is associated with high morbidity and mortality, and an increased risk of…”
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Aortic Valve Stenosis in a Dialysis Patient Waitlisted for Kidney Transplantation by Büttner, Stefan, MD, Weiler, Helge, MD, Zöller, Carolin, Koch, Benjamin, MD, Zierer, Andreas, MD, Zeiher, Andreas M., MD, Geiger, Helmut, MD, Vasa-Nicotera, Mariuca, MD, Hauser, Ingeborg A., MD, Fichtlscherer, Stephan, MD

“…Management of dialysis patients with valvular heart disease waitlisted for kidney transplantation is challenging. Development of severe aortic valve stenosis…”
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Nephropathy in Illicit Drug Abusers: A Postmortem Analysis by Buettner, Maike, MD, Toennes, Stefan W., PhD, Buettner, Stefan, MD, Bickel, Markus, MD, Allwinn, Regina, MD, Geiger, Helmut, MD, Bratzke, Hansjuergen, MD, Amann, Kerstin, MD, Jung, Oliver, MD

“…Background Illicit drug abuse is an independent risk factor for chronic kidney disease, but the pathogenic consequences of long-term exposure to illicit drugs…”
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