Search Results - "GEFFEN, D. B"

The impact of the 21-gene recurrence score assay on decision making about adjuvant chemotherapy in early-stage estrogen-receptor-positive breast cancer in an oncology practice with a unified treatment policy by Geffen, D.B., Abu-Ghanem, S., Sion-Vardy, N., Braunstein, R., Tokar, M., Ariad, S., Delgado, B., Bayme, M., Koretz, M.

“…The 21-gene recurrence score (RS) assay has been validated in retrospective studies as prognostic of distant disease recurrence and predictive of the benefit…”
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Should decisions on adding adjuvant chemotherapy in early-stage ER-positive breast cancer be based on gene expression testing or clinicopathologic factors or both? by Geffen, D.B.

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Prophylactic irradiation to the contralateral breast for BRCA mutation carriers with early-stage breast cancer by Evron, E., Ben-David, A.M., Goldberg, H., Fried, G., Kaufman, B., Catane, R., Pfeffer, M.R., Geffen, D.B., Chernobelsky, P., Karni, T., Abdah-Bortnyak, R., Rosengarten, O., Matceyevsky, D., Inbar, M., Kuten, A., Corn, B.W.

“…Women who carry germ-line mutations in BRCA1/2 are at very high risk of developing breast and ovarian cancer. Breast conserving therapy is associated with a…”
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Cutaneous photosensitivity induced by paclitaxel and trastuzumab therapy associated with aberrations in the biosynthesis of porphyrins by Cohen, A. D., Mermershtain, W., Geffen, D. B., Schoenfeld, N., Mamet, R., Cagnano, E., Cohen, Y., Halevy, S.

“…Background: Paclitaxel and trastuzumab are new treatments for patients with metastatic breast cancer. Case report: We describe here a 40-year-old female…”
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Adjuvant aromatase inhibitor therapy in patients with stage I breast cancer at a regional oncology center in Israel: implementation of a 'switching' policy in postmenopausal patients after initial tamoxifen by Geffen, D B, Tokar, M, Abu-Ghanem, S, Braunstein, R, Koretz, M, Amir, N, Delgado, B, Sion-Vardi, N, Ariad, S, Lazarev, I

“…To analyze the implementation of a switching policy of adjuvant aromatase inhibitor (AI) therapy sequentially after tamoxifen in consecutively treated stage I…”
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Irinotecan Combined with Bolus 5-Fluorouracil and Folinic Acid for Metastatic Colorectal Cancer: Is This Really a Dangerous Treatment? by Idelevich, E., Man, S., Lavrenkov, K., Gluzman, A., Geffen, D.B., Shani, A.

“…Rothenberg et al 1 called for caution in the palliative use of irinotecan, 5-fluorouracil (5-FU) bolus and leucovorin (IFL schedule), because of early…”
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Gemcitabine-induced severe extremity edema with muscle contractures and subsequent prevention with prednisone by Geffen, D B, Horowitz, J

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Chemotherapy with Irinothecan, 5-Fluorouracil and Folinic Acid in the First-Line Management of Advanced Colorectal Carcinoma: Retrospective Study by Man, S., Lavrenkov, K., Gluzman, A., Geffen, D.B., Cohen, Y.

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Primary Malignant Lymphoma of the Prostate - A Report of Three Cases by Mermershtain, Wilmosh, Benharroch, Daniel, Lavrenkov, Konstantin, Geffen, David B., German, Igor, Cohen, Yoram

“…We report the clinical, morphological and immunohistochemical findings in 3 cases of primary non-Hodgkins malignant lymphoma of the prostate. After treatment…”
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Stage I breast cancer in a regional oncology practice in Israel 2002–2006: Clinicopathologic features, risk estimation and planned therapy of 328 consecutive patients by Geffen, D.B, Amir, N, Sion-Vardy, N, Ariad, S, Kachko, L, Bayme, M, Delgado, B, Dyomin, V, Argov, S, Koretz, M

“…Abstract We present the clinicopathologic features and treatment plans of 328 consecutive stage I (T1N0M0) breast cancer patients seen at a regional medical…”
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Testicular carcinoma with inferior vena cava thrombosis extending into the right atrium treated with chemotherapy and anticoagulation by Geffen, D B, Kaneti, J, Hendler, N, Hertzanu, Y

“…A 34-year-old male with pulmonary emboli and thrombosis of the inferior vena cava extending into the right atrium was found at presentation to have a mixed…”
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Myasthenia Gravis Associated with Malignant Mixed Mullerian Tumor of the Uterus by Ariad, Samuel, Geffen, David B., Yanai-Inbar, Ilana, Zalmanov, Swetlana, Piura, Benjamin

“…Myasthenia gravis is a neurologic disorder characterized by intermittent muscle weakness which improves after anticholinesterase medication. The pathogenesis…”
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Doxorubicin cardiomyopathy: underlying cause of interferon-induced cardiac dysfunction? by Geffen, D B, Liel-Cohen, N

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Expression of c-myc and c-ras oncogenes in the neoplastic and non-neoplastic cells of Hodgkin's disease by Benharroch, D, Yermiahu, T, Geffen, D B, Prinsloo, I, Gopas, J, Segal, S, Aboud, M

“…The oncogenes c-myc and c-ras are known to elicit a cooperative tumorigenicity. In this study we investigated their role in the pathogenesis of Hodgkin's…”
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Gluteal manifestation of advanced Hodgkin's disease by ARIAD, S, HATSKELZON, L, BENHARROCH, D, GEFFEN, D. B

“…Hodgkin's disease (HD) is a nodal malignancy with a characteristically axial pattern of spread and with contiguous progression via lymphatic channels. Even…”
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Metastatic angiosarcoma of the spleen after accidental radiation exposure: A case report by GEFFEN, D. B, ZIRKIN, H. J, MERMERSHTAIN, W, COHEN, Y, ARIAD, S

“…Angiosarcoma is a rare malignant tumor arising from endothelial cells of blood vessels or lymphatic channels. Therapeutic irradiation, thoriumdioxide…”
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Small cell carcinoma of the breast: case report by Shaco-Levy, R, Dyomin, V, Kachko, L, Sion-Vardy, N, Geffen, D B, Koretz, M

“…Small cell neuroendocrine carcinoma of the breast is a rare tumor with fewer than 30 cases reported in the literature. The reported age of incidence of mammary…”
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Pulmonary lymphangioleiomyomatosis. Report of a case with associated multiple soft-tissue tumors by Cagnano, M, Benharroch, D, Geffen, D B

“…We describe a 55-year-old woman with pulmonary lymphangioleiomyomatosis. The patient died of respiratory failure 9 years after diagnosis. An autopsy confirmed…”
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Primary small noncleaved cell lymphoma of the liver. Report of an adult case in complete remission after treatment with combination chemotherapy by Stemmer, S, Geffen, D B, Goldstein, J, Cohen, Y

“…Open liver biopsy in a 34-year-old woman with hepatosplenomegaly showed small noncleaved cell lymphoma. Except for an enlarged spleen, there was no evidence of…”
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Basal Cell Carcinoma of the Male Nipple Case Report and Review of the Literature by BENHARROCH, DANIEL, GEFFEN, DAVID B., PEISER, JOHANAN, ROSENBERG, LIOR

“…background. Basal cell carcinoma (BCC) of the nipple is a very unusual occurence, often mistaken for Paget's disease. objective. By reporting a further case of…”
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