Search Results - "GAVRAS, HARALAMBOS"

Cell Signaling, Internalization, and Nuclear Localization of the Angiotensin Converting Enzyme in Smooth Muscle and Endothelial Cells by Lucero, Héctor A., Kintsurashvili, Ekaterina, Marketou, Maria E., Gavras, Haralambos

“…The angiotensin converting enzyme (ACE) catalyzes the extracellular formation of angiotensin II, and degradation of bradykinin, thus regulating blood pressure…”
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The α2-adrenergic receptors in hypertension and heart failure: experimental and clinical studies by Gavras, Irene, Manolis, Athanasios J, Gavras, Haralambos

“…This is a brief overview of experimental and clinical studies exploring the hemodynamic functions of the α2A and α2B adrenergic receptor (AR) subtypes in…”
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Cardioprotective properties of bradykinin: role of the B2 receptor by Manolis, Athanasios J, Marketou, Maria E, Gavras, Irene, Gavras, Haralambos

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Issues in hypertension: drug tolerability and special populations by Gavras, Haralambos P

“…Improvements in the death rate from coronary heart disease and in the control of hypertension have leveled off in recent years, reversing a trend toward steady…”
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Role of Angiotensin and Its Inhibition in Hypertension, Ischemic Heart Disease, and Heart Failure by Gavras, Haralambos, Brunner, Hans R

“…This is a personal historical account relating the events that led to the first application of angiotensin inhibition (either by ACE inhibitors or by…”
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Models of Experimental Hypertension in Mice by Johns, Conrado, Gavras, Irene, Handy, Diane E, Salomao, Abrahao, Gavras, Haralambos

“…Experimental models of hypertension in various animals are useful in the research of vasoactive mechanisms. Recombinant DNA technology has produced genetically…”
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Genetic analysis of blood pressure in C3H/HeJ and SWR/J mice by DiPetrillo, Keith, Tsaih, Shirng-Wern, Sheehan, Susan, Johns, Conrado, Kelmenson, Peter, Gavras, Haralambos, Churchill, Gary A, Paigen, Beverly

“…1 The Jackson Laboratory, Bar Harbor, Maine 04609 2 Hypertension Section, Boston University School of Medicine, Boston, Massachusetts 02118 Hypertension is a…”
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A role for the A3 adenosine receptor in determining tissue levels of cAMP and blood pressure: studies in knock-out mice by Zhao, Zhihui, Makaritsis, Konstantinos, Francis, Cynthia E, Gavras, Haralambos, Ravid, Katya

“…Adenosine administration has been reported to lower blood pressure by activating specific membrane receptors. The rat and human heart and aorta have been…”
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‘Volume-expanded’ hypertension: the effect of fluid overload and the role of the sympathetic nervous system in salt-dependent hypertension by Gavras, Irene, Gavras, Haralambos

“…It is widely believed that salt-dependent hypertension is induced and maintained by expansion of intravascular fluid volume resulting from excessive retention…”
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Evidence for Linkage Between Essential Hypertension and a Putative Locus on Human Chromosome 17 by Baima, Jader, Nicolaou, Michael, Schwartz, Faina, DeStefano, Anita L, Manolis, Athanasios, Gavras, Irene, Laffer, Cheryl, Elijovich, Fernando, Farrer, Lindsay, Baldwin, Clinton T, Gavras, Haralambos

“…Several clinical and animal studies indicate that essential hypertension is inherited as a multifactorial trait with a significant genetic and environmental…”
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Localization of α2A- and α2B-adrenergic receptor subtypes in brain by TAVARES, A, HANDY, D. E, BOGDANOVA, N. N, ROSENE, D. L, GABRAS, H

“…Abstract Recent studies have shown that all three subtypes of α 2 -adrenergic receptor (α 2 -AR) are found in brain. The purpose of this study was to map the…”
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Abstract P109: A Promising Novel Hypertension Drug Candidate by Gavras, Haralambos, Neutel, Joel, Elin, Ronald J, Rosanoff, Andrea, Costello, Rebecca B, Mani, Jayashree, Jaffe, Russell

“…This study tests the hypothesis that RMJH-111b, a novel drug candidate, can improve blood pressure (BP) in hypertensive adults without the gastrointestinal…”
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A 2b Adenosine Receptor Regulates Hyperlipidemia and Atherosclerosis by Koupenova, Milka, Johnston-Cox, Hillary, Vezeridis, Alexander, Gavras, Haralambos, Yang, Dan, Zannis, Vassilis, Ravid, Katya

“…Background— The cAMP-elevating A 2b adenosine receptor (A 2b AR) controls inflammation via its expression in bone marrow cells. Methods and Results—…”
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Potent antiproliferative activity of bradykinin B2 receptor selective agonist FR-190997 and analogue structures thereof: A paradox resolved? by Rassias, Gerasimos, Leonardi, Sofia, Rigopoulou, Dionisia, Vachlioti, Eleanna, Afratis, Konstantinos, Piperigkou, Zoi, Koutsakis, Christos, Karamanos, Nikos K., Gavras, Haralambos, Papaioannou, Dionissios

“…Βradykinin stimulation of B2 receptor is known to activate the oncogenic ERK pathway and overexpression of bradykinin receptors B1 and B2 has been reported to…”
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Independence and reproducibility across microarray platforms by Quackenbush, John, Larkin, Jennie E, Frank, Bryan C, Gavras, Haralambos, Sultana, Razvan

“…Microarrays have been widely used for the analysis of gene expression, but the issue of reproducibility across platforms has yet to be fully resolved. To…”
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Benefits and side effects of blood pressure lowering treatment: what was wrong with doxazosin in the ALLHAT? by Gavras, Irene, Gavras, Haralambos

“…The lowering of high blood pressure is supposed to protect target organs from hypertensive damage. The Antihypertensive and Lipid Lowering Treatment to Prevent…”
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Artificial Intelligence Guided Studies of van der Waals Magnets by Rhone, Trevor David, Bhattarai, Romakanta, Gavras, Haralambos, Lusch, Bethany, Salim, Misha, Mattheakis, Marios, Larson, Daniel T., Krockenberger, Yoshiharu, Kaxiras, Efthimios

“…A materials informatics framework to explore a large number of candidate van der Waals (vdW) materials is developed. In particular, in this study a large space…”
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The [A.sub.2B] adenosine receptor protects against inflammation and excessive vascular adhesion by Yang, Dan, Zhang, Ying, Nguyen, Hao G, Koupenova, Milka, Chauhan, Anil K, Makitalo, Maria, Jones, Matthew R, St. Hilaire, Cynthia, Seldin, David C, Toselli, Paul, Lamperti, Edward, Schreiber, Barbara M, Gavras, Haralambos, Wagner, Denisa D, Ravid, Katya

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Artificial Intelligence Guided Studies of van der Waals Magnets (Adv. Theory Simul. 6/2023) by Rhone, Trevor David, Bhattarai, Romakanta, Gavras, Haralambos, Lusch, Bethany, Salim, Misha, Mattheakis, Marios, Larson, Daniel T., Krockenberger, Yoshiharu, Kaxiras, Efthimios

“…Searching for novel two‐dimensional magnets using AI Intrinsic magnetic ordering in two dimensions was discovered in 2017 when a single layer of CrI3 and two…”
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The A2B adenosine receptor protects against inflammation and excessive vascular adhesion by Yang, Dan, Zhang, Ying, Nguyen, Hao G, Koupenova, Milka, Chauhan, Anil K, Makitalo, Maria, Jones, Matthew R, St Hilaire, Cynthia, Seldin, David C, Toselli, Paul, Lamperti, Edward, Schreiber, Barbara M, Gavras, Haralambos, Wagner, Denisa D, Ravid, Katya

“…Adenosine has been described as playing a role in the control of inflammation, but it has not been certain which of its receptors mediate this effect. Here, we…”
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