Search Results - "GAUTAM, DINESH"

Optimal antiplatelet strategy in Asian patients presenting with acute coronary syndrome by Choudhary, Rahul, Gautam, Dinesh K.

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Muscarinic acetylcholine receptors: mutant mice provide new insights for drug development by Wess, Jürgen, Eglen, Richard M, Gautam, Dinesh

“…Muscarinic acetylcholine receptors (mAChRs), M(1)-M(5), regulate the activity of numerous fundamental central and peripheral functions. The lack of…”
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chemical-genetic approach to study G protein regulation of β cell function in vivo by Guettier, Jean-Marc, Gautam, Dinesh, Scarselli, Marco, de Azua, Inigo Ruiz, Li, Jian Hua, Rosemond, Erica, Ma, Xiaochao, Gonzalez, Frank J, Armbruster, Blaine N, Lu, Huiyan, Roth, Bryan L, Wess, Jürgen

“…Impaired functioning of pancreatic β cells is a key hallmark of type 2 diabetes. β cell function is modulated by the actions of different classes of…”
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Cardiovascular complications and its impact on outcomes in COVID-19 by Kunal, Shekhar, Sharma, Shashi Mohan, Sharma, Sohan Kumar, Gautam, Dinesh, Bhatia, Harnish, Mahla, Himanshu, Sharma, Sandeep, Bhandari, Sudhir

“…Coronavirus disease 2019 (COVID-19) has led to a widespread morbidity and mortality. Limited data exists regarding the involvement of cardiovascular system in…”
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Axial flow hollow fiber forward osmosis module analysis for optimum design and operating conditions in desalination applications by Teklu, Habtom, Gautam, Dinesh Kumar, Subbiah, Senthilmurugan

“…[Display omitted] •Hollow fiber membrane characterization using forward osmosis experimental data.•Mathematical model development for axial flow hollow fiber…”
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A Novel Experimental Strategy to Assess the Metabolic Effects of Selective Activation of a Gq-Coupled Receptor in Hepatocytes In Vivo by Hua Li, Jian, Jain, Shalini, McMillin, Sara M, Cui, Yinghong, Gautam, Dinesh, Sakamoto, Wataru, Lu, Huiyan, Jou, William, McGuinness, Owen P, Gavrilova, Oksana, Wess, Jürgen

“…Increased hepatic glucose production is a key pathophysiological feature of type 2 diabetes. Like all other cell types, hepatocytes express many G…”
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Antimicrobial studies, synthesis and characterization of novel 1-nitro-10H-phenothiazine bearing sulfone/nucleoside moieties by Jangid, Dinesh Kumar, Guleria, Anjali, Gautam, Dinesh C., Yadav, Hemendra, Mathur, Manas, Swami, Ajit Kumar

“…The current research article involves one pot synthesis of novel substituted 1-nitro-10H-phenothiazines via Smiles rearrangement. These substituted…”
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Herbicidal Effects of Chenopodium murale and Coronopus didymus Sm. Residues Against Germination and Early Growth of Hordeum vulgare by Kumar Gautam, Dinesh, Kumar Singh, Dushyant, University Jhansi, Bundelkhand, Kumar Agnihotri, Rajneesh

“…This study reports the common problems of weed species that adversely affect the crop productivity of the agriculture crops at a large scale. The purpose of…”
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Role for Neuronal Insulin Resistance in Neurodegenerative Diseases by Schubert, Markus, Gautam, Dinesh, Surjo, David, Ueki, Kojihiko, Baudler, Stephanie, Schubert, Dominic, Kondo, Tatsuya, Alber, Jens, Galldiks, Norbert, Küstermann, Eckehardt, Arndt, Saskia, Jacobs, Andreas H., Krone, Wilhelm, Kahn, C. Ronald, Brüning, Jens C.

“…Impairment of insulin signaling in the brain has been linked to neurodegenerative diseases. To test the hypothesis that neuronal insulin resistance contributes…”
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Distributed parameter system modeling approach for the characterization of a high flux hollow fiber forward osmosis (HFFO) membrane by Munubarthi, Kranthi Kumar, Gautam, Dinesh Kumar, Anki Reddy, K., Subbiah, Senthilmurugan

“…In this work, the performance of a commercially available Aquaporin incorporated axial flow Hollow Fiber Forward Osmosis (HFFO) membrane is studied for NaCl –…”
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Synthesis and antitubercular screening of some novel 4H-1,4- benzothiazines and their sulfones under environment benign solvent free conditions as future anti-tubercular agents by Guleria, Anjali, Jangid, Dinesh K, Gautam, Naveen, Lakhotia, Richa, Chowdhary, Abhay, Gautam, Dinesh C

“…Some novel analogs of 4H-1,4-benzothiazines were synthesized under environmentally benign solvent free conditions by one pot oxidative cyclocondensation of…”
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Muscarinic Stimulation of Pancreatic Insulin and Glucagon Release Is Abolished in M3 Muscarinic Acetylcholine Receptor–Deficient Mice by DUTTAROY, Alokesh, ZIMLIKI, Charles L, GAUTAM, Dinesh, YINGHONG CUI, MEARS, David, WESS, Jürgen

“…Muscarinic Stimulation of Pancreatic Insulin and Glucagon Release Is Abolished in M 3 Muscarinic Acetylcholine Receptor–Deficient Mice Alokesh Duttaroy 1 ,…”
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RGS4 is a negative regulator of insulin release from pancreatic β-cells in vitro and in vivo by Ruiz de Azua, Inigo, Scarselli, Marco, Rosemond, Erica, Gautam, Dinesh, Jou, William, Gavrilova, Oksana, Ebert, Philip J, Levitt, Pat, Wess, Jürgen

“…Therapeutic strategies that augment insulin release from pancreatic β-cells are considered beneficial in the treatment of type 2 diabetes. We previously…”
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Role of Brain Insulin Receptor in Control of Body Weight and Reproduction by Brüning, Jens C., Gautam, Dinesh, Burks, Deborah J., Gillette, Jennifer, Schubert, Markus, Orban, Paul C., Klein, Rüdiger, Krone, Wilhelm, Müller-Wieland, Dirk, Kahn, C. Ronald

“…Insulin receptors (IRs) and insulin signaling proteins are widely distributed throughout the central nervous system (CNS). To study the physiological role of…”
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Awareness, treatment adherence and risk predictors of uncontrolled hypertension at a tertiary care teaching hospital in Western India by Choudhary, Rahul, Sharma, Shashi Mohan, Kumari, Vimla, Gautam, Dinesh

“…Abstract Introduction Hypertension still remains poorly controlled. Result Adequate BP control was achieved in 37.4% of patients and significant attributes for…”
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Cholinergic stimulation of salivary secretion studied with M1 and M3 muscarinic receptor single- and double-knockout mice by Gautam, Dinesh, Heard, Thomas S, Cui, Yinghong, Miller, Georgina, Bloodworth, Lanh, Wess, Jürgen

“…Identification of the specific muscarinic acetylcholine receptor (mAChR) subtypes mediating stimulation of salivary secretion is of considerable clinical…”
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Hepatic Muscarinic Acetylcholine Receptors Are Not Critically Involved in Maintaining Glucose Homeostasis in Mice by Li, Jian H, Gautam, Dinesh, Han, Sung-Jun, Guettier, Jean-Marc, Cui, Yinghong, Lu, Huiyan, Deng, Chuxia, O'Hare, James, Jou, William, Gavrilova, Oksana, Buettner, Christoph, Wess, Jürgen

“…Hepatic Muscarinic Acetylcholine Receptors Are Not Critically Involved in Maintaining Glucose Homeostasis in Mice Jian H. Li 1 , Dinesh Gautam 1 , Sung-Jun Han…”
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Kinetic Model under Light-Limited Condition for Photoinitiated Thiol–Ene Coupling Reactions by Sy Piecco, Kurt W. E, Aboelenen, Ahmed M, Pyle, Joseph R, Vicente, Juvinch R, Gautam, Dinesh, Chen, Jixin

“…Thiol–ene click chemistry has become a powerful paradigm in synthesis, materials science, and surface modification in the past decade. In the photoinitiated…”
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Muscarinic acetylcholine receptor knockout mice show distinct synaptic plasticity impairments in the visual cortex by Origlia, Nicola, Kuczewski, Nicola, Aztiria, Eugenio, Gautam, Dinesh, Wess, Jürgen, Domenici, Luciano

“…In the present report, we focused our attention on the role played by the muscarinic acetylcholine receptors (mAChRs) in different forms of long-term synaptic…”
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Estradiol treatment induces testicular oxidative stress and germ cell apoptosis in rats by Chaki, S P, Misro, M M, Gautam, Dinesh K, Kaushik, Mahesh, Ghosh, D, Chainy, G B

“…In order to understand the pathogenesis of estradiol induced effects in the seminiferous epithelium, studies were undertaken in adult rats with…”
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