Search Results - "GAUDRIAULT, Georges"

Proof-of-concept study for a long-acting formulation of ivermectin injected in cattle as a complementary malaria vector control tool by Pooda, Sié Hermann, Moiroux, Nicolas, Porciani, Angélique, Courjaud, Anne-Laure, Roberge, Christophe, Gaudriault, Georges, Sidibé, Issa, Belem, Adrien Marie Gaston, Rayaissé, Jean-Baptiste, Dabiré, Roch K, Mouline, Karine

“…Domesticated animals play a role in maintaining residual transmission of Plasmodium parasites of humans, by offering alternative blood meal sources for malaria…”
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Effects of an injectable long-acting formulation of ivermectin on Onchocerca ochengi in zebu cattle by Boussinesq, Michel, Enyong, Peter, Chounna-Ndongmo, Patrick, Njouendou, Abdel-Jelil, Pion, Sébastien David, Rech, Anthony, Roberge, Christophe, Gaudriault, Georges, Wanji, Samuel

“…The availability of a safe macrofilaricidal drug would help to accelerate onchocerciasis elimination. A trial was conducted in Cameroon to evaluate the effects…”
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Regulation of Corticotropin-Releasing Factor Receptor Type 2β Messenger Ribonucleic Acid in the Rat Cardiovascular System by Urocortin, Glucocorticoids, and Cytokines by Kageyama, Kazunori, Gaudriault, Georges E., Bradbury, Margaret J., Vale, Wylie W.

“…Abstract CRF receptor type 2 (CRF R2) messenger RNA (mRNA) expression in the rodent heart is modulated by exposure to both the bacterial endotoxin…”
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Regulation of corticotropin-releasing factor receptor type 2β mRNA via cyclic AMP pathway in A7r5 aortic smooth muscle cells by Kageyama, Kazunori, Gaudriault, Georges E, Suda, Toshihiro, Vale, Wylie W

“…Corticotropin-releasing factor receptor type 2β (CRF R2β) is a member of the Class B heptahelical G protein-coupled receptors. This receptor is positively…”
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Novel Rap1 dominant-negative mutants interfere selectively with C3G and Epac by DUPUY, Aurélien G, L'HOSTE, Sébastien, CHERFILS, Jacqueline, CAMONIS, Jacques, GAUDRIAULT, Georges, DE GUNZBURG, Jean

“…Rap1 is a Ras-related GTPase that is principally involved in integrin- and E-cadherin-mediated adhesion. Rap1 is transiently activated in response to many…”
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Retroinverso analogs of spadin display increased antidepressant effects by Veyssiere, Julie, Moha ou Maati, Hamid, Mazella, Jean, Gaudriault, Georges, Moreno, Sébastien, Heurteaux, Catherine, Borsotto, Marc

“…Rationale Although depression is the most common mood disorder, only one third of patients are treated with success. Finding new targets, new drugs, and also…”
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The RGS (regulator of G-protein signalling) and GoLoco domains of RGS14 co-operate to regulate Gi-mediated signalling by Traver, Sabine, Splingard, Anne, Gaudriault, Georges, De Gunzburg, Jean

“…RGS (regulator of G-protein signalling) proteins stimulate the intrinsic GTPase activity of the a subunits of heterotrimeric G-proteins, and thereby negatively…”
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Differential internalization of somatostatin in COS-7 cells transfected with SST1 and SST2 receptor subtypes : A confocal microscopic study using novel fluorescent somatostatin derivatives by NOUEL, D, GAUDRIAULT, G, HOULE, M, REISINE, T, VINCENT, J.-P, MAZELLA, J, BEAUDET, A

“…A growing body of evidence suggests that neuropeptide binding to G protein-linked receptors may result in internalization of receptor-ligand complexes,…”
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Regulation of corticotropin-releasing factor receptor type 2beta mRNA via cyclic AMP pathway in A7r5 aortic smooth muscle cells by Kageyama, Kazunori, Gaudriault, Georges E, Suda, Toshihiro, Vale, Wylie W

“…Corticotropin-releasing factor receptor type 2beta (CRF R2beta) is a member of the Class B heptahelical G protein-coupled receptors. This receptor is…”
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Receptor-induced Internalization of Selective Peptidic μ and Δ Opioid Ligands by Gaudriault, Georges, Nouel, Dominique, Farra, Claude Dal, Beaudet, Alain, Vincent, Jean-Pierre

“…The binding and internalization of radioiodinated and fluorescent μ and Δ opioid peptides in mammalian cells were quantitatively studied by biochemical…”
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Somatodendritic internalization and perinuclear targeting of neurotensin in the mammalian brain by Faure, MP, Alonso, A, Nouel, D, Gaudriault, G, Dennis, M, Vincent, JP, Beaudet, A

“…Polypeptide hormones and growth factors have long been known to internalize into peripheral target cells as a result of their interaction with cell surface…”
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Regulation of Corticotropin-Releasing Factor Receptor Type 2β Messenger Ribonucleic Acid in the Rat Cardiovascular System by Urocortin, Glucocorticoids, and Cytokines1 by Kageyama, Kazunori, Gaudriault, Georges E, Bradbury, Margaret J, Vale, Wylie W

“…CRF receptor type 2 (CRF R2) messenger RNA (mRNA) expression in the rodent heart is modulated by exposure to both the bacterial endotoxin lipopolysaccharide…”
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Selective labeling of alpha- or epsilon-amino groups in peptides by the Bolton-Hunter reagent by Gaudriault, G, Vincent, J P

“…Incorporation of N-succinimidyl-3(4-hydroxyphenyl) propionate (Bolton-Hunter reagent) or its 125I-labeled derivative into peptides can be selectively directed…”
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Implication of various forms of neurotensin receptors in the mechanism of internalization of neurotensin in cerebral neurons by CHABRY, J, GAUDRIAULT, G, VINCENT, J.-P, MAZELLA, J

“…This report describes the kinetics and molecular aspects of neurotensin internalization in neurons. Incubation of alpha-125I-Bolton-Hunter neurotensin-(2-13)…”
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Receptor-induced Internalization of Selective Peptidic μ and δ Opioid Ligands by Georges Gaudriault, Dominique Nouel, Claude Dal Farra, Alain Beaudet, Jean-Pierre Vincent

“…The binding and internalization of radioiodinated and fluorescent μ and δ opioid peptides in mammalian cells were quantitatively studied by biochemical…”
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Differential Internalization of Somatostatin in COS-7 Cells Transfected with SST1 and SST2 Receptor Subtypes: A Confocal Microscopic Study Using Novel Fluorescent Somatostatin Derivatives1 by Nouel, Dominique, Gaudriault, Georges, Houle, Mariette, Reisine, Terry, Vincent, Jean-Pierre, Mazella, Jean, Beaudet, Alain

“…A growing body of evidence suggests that neuropeptide binding to G protein-linked receptors may result in internalization of receptor-ligand complexes,…”
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Differential Internalization of Somatostatin in COS-7 Cells Transfected with SST 1 and SST 2 Receptor Subtypes: A Confocal Microscopic Study Using Novel Fluorescent Somatostatin Derivatives 1 by Nouel, Dominique, Gaudriault, Georges, Houle, Mariette, Reisine, Terry, Vincent, Jean-Pierre, Mazella, Jean, Beaudet, Alain

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Preparation and Binding Properties of Radioiodinated Analogues of Dermorphin and Deltorphin with High Specificity for the μ‐ and δ‐Opioid Receptors by Gaudriault, Georges, Zsürger, Nicole, Vincent, Jean‐Pierre

“…: The synthesis, purification, chemical characterization, and binding properties of two 125I‐labeled analogues of dermorphin and deltorphin‐I are described…”
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Radiolabeled ligands specific for the G protein-coupled state of neurotensin receptors by Gaudriault, G, Zsürger, N, Vincent, J P

“…Radiolabeled analogues of neuromedin N have been prepared by acylation of the alpha, epsilon 1, and epsilon 2 amino groups of [Lys2]neuromedin N…”
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Compared binding properties of 125I-labeled analogues of neurotensin and neuromedin N in rat and mouse brain by Gaudriault, G, Zsürger, N, Vincent, J P

“…Neurotensin and neuromedin N are two structurally related peptides that are synthesized by a common precursor. The purpose of the present work was to…”
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