Search Results - "GASDASKA, J. R"

Transferrin in a cockroach: molecular cloning, characterization, and suppression by juvenile hormone by Jamroz, Robert C., Gasdaska, John R., Bradfield, James Y., Law, John H.

“…In a study of juvenile hormone-regulated gene expression, we isolated an anonymous cDNA representing a message that was strongly suppressed by juvenile hormone…”
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Thioredoxin and thioredoxin reductase gene expression in human tumors and cell lines, and the effects of serum stimulation and hypoxia by Berggren, M, Gallegos, A, Gasdaska, J R, Gasdaska, P Y, Warneke, J, Powis, G

“…Thioredoxin and thioredoxin reductase are redox proteins that have been implicated in the control of cell proliferation and transformation. We report the…”
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Mechanisms of the regulation of thioredoxin reductase activity in cancer cells by the chemopreventive agent selenium by GALLEGOS, A, BERGGREN, M, GASDASKA, J. R, POWIS, G

“…Selenium is an essential trace element, the deficiency of which is associated with an increased incidence of some human cancers. Dietary supplementation with…”
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Transfection with human thioredoxin increases cell proliferation and a dominant-negative mutant thioredoxin reverses the transformed phenotype of human breast cancer cells by GALLEGOS, A, GASDASKA, J. R, TAYLOR, C. W, PAINE-MURRIETA, G. D, GOODMAN, D, GASDASKA, P. Y, BERGGREN, M, BRIEHL, M. M, POWIS, G

“…Thioredoxin, a redox protein with growth factor activity that modulates the activity of several proteins important for cell growth, has been reported to be…”
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Cell growth stimulation by the redox protein thioredoxin occurs by a novel helper mechanism by GASDASKA, J. R, BERGGREN, M, POWIS, G

“…Thioredoxins are a class of low molecular weight redox proteins that undergo reversible reduction-oxidation of two active-site cysteine residues with reduction…”
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Human Thioredoxin Reductase Gene Localization to Chromosomal Position 12q23–q24.1 and mRNA Distribution in Human Tissue by Gasdaska, John R., Gasdaska, Pamela Y., Gallegos, Alfred, Powis, Garth

“…Thioredoxin reductase is a member of the pyridine nucleotide–disulfide oxidoreductase family of enzymes. By delivering reducing equivalents to thioredoxin,…”
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Selenium and the thioredoxin redox system: effects on cell growth and death by Powis, G, Gasdaska, J R, Gasdaska, P Y, Berggren, M, Kirkpatrick, D L, Engman, L, Cotgreave, I A, Angulo, M, Baker, A

“…Thioredoxin is a redox protein found overexpressed in some human tumors. Thioredoxin is secreted by tumor cells and enhances the sensitivity of the cancer…”
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Oxidative inactivation of thioredoxin as a cellular growth factor and protection by a Cys73 → ser mutation by GASDASKA, J. R, KIRKPATRICK, D. L, MONTFORT, W, KUPERUS, M, HILL, S. R, BERGGREN, M, POWIS, G

“…Thioredoxin (Trx) is a widely distributed redox protein that regulates several intracellular redox-dependent processes and stimulates the proliferation of both…”
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Crystal structures of reduced, oxidized, and mutated human thioredoxins: evidence for a regulatory homodimer by Weichsel, Andrzej, Gasdaska, John R, Powis, Garth, Montfort, William R

“…Background: Human thioredoxin reduces the disulfide bonds of numerous proteins in vitro, and can activate transcription factors such as NF κB in vivo…”
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Cloning and sequencing of a human thioredoxin reductase by Gasdaska, Pamela Y., Gasdaska, John R., Cochran, Shawn, Powis, Garth

“…The DNA sequence encoding human placental thioredoxin reductase has been determined. Of the 3826 base pairs sequenced, 1650 base pairs were in an open reading…”
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Redox signaling and the control of cell growth and death by Powis, G, Gasdaska, J R, Baker, A

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Regulation of Human Thioredoxin Reductase Expression and Activity by 3′-Untranslated Region Selenocysteine Insertion Sequence and mRNA Instability Elements by Gasdaska, John R., Harney, John W., Gasdaska, Pamela Y., Powis, Garth, Berry, Marla J.

“…Thioredoxin reductases function in regulating cellular redox and function through their substrate, thioredoxin, in the proper folding of enzymes and redox…”
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Effect of selenium on rat thioredoxin reductase activity: Increase by supranutritional selenium and decrease by selenium deficiency by Berggren, Margareta M, Mangin, José F, Gasdaska, John R, Powis, Garth

“…Thioredoxin reductase is a newly identified selenocysteine-containing enzyme that catalyzes the NADPH-dependent reduction of the redox protein thioredoxin…”
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Human Thioredoxin Homodimers:  Regulation by pH, Role of Aspartate 60, and Crystal Structure of the Aspartate 60 → Asparagine Mutant by Andersen, John F, Sanders, David A. R, Gasdaska, John R, Weichsel, Andrzej, Powis, Garth, Montfort, William R

“…Thioredoxins are a group of ca. 12 kDa redox proteins that mediate numerous cytosolic processes in all cells. Human thioredoxin can be exported out of the cell…”
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Ortho-functionalization of aromatic ketones via manganation. A synthesis of indenols by Liebeskind, Lanny S, Gasdaska, John R, McCallum, J. Stuart, Tremont, Samuel J

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Cockroach transferrin closely resembles vertebrate transferrins in its metal ion-binding properties: A spectroscopic study by Gasdaska, John R., Law, John H., Bender, Christopher J., Aisen, Philip

“…The optical and electron paramagnetic resonance (EPR) spectroscopic properties of a transferrin from the cockroach Blaberus discoidalis have been investigated…”
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A dipolar cycloaddition approach to pyrrolo[1,2-a]indoles using N-[(trimethylsilyl)methyl]-substituted indoles by Padwa, Albert, Fryxell, Glen E, Gasdaska, John R, Venkatramanan, M. K, Wong, George S. K

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A new approach to pyrrolo[1,2-a]indoles using azomethine ylides by Padwa, Albert, Gasdaska, John R

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Silyl-substituted thioimidates as nitrile ylide equivalents by Padwa, Albert, Gasdaska, John R, Hoffmanns, Gunter, Rebello, Hector

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[2,3]-Sigmatropic rearrangement of sulfur ylides derived from trimethylsilyl sulfonium salts by Padwa, Albert, Gasdaska, John R

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