Search Results - "GARRIDO, Ignacio"

Pancreatic cancer: from state-of-the-art treatments to promising novel therapies by Garrido-Laguna, Ignacio, Hidalgo, Manuel

“…Key Points Patient survival after resection of pancreatic ductal adenocarcinoma (PDAC) remains poor and more-effective adjuvant treatments are desperately…”
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Immune Checkpoint Inhibitors in Combinations for Hepatocellular Carcinoma by Kalasekar, Sharanya Maanasi, Garrido‐Laguna, Ignacio, Evason, Kimberley Jane, Corey, Kathleen E., Malhi, Harmeet

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Multiagent induction chemotherapy followed by chemoradiation is associated with improved survival in locally advanced pancreatic cancer by Torgeson, Anna, Lloyd, Shane, Boothe, Dustin, Tao, Randa, Whisenant, Jonathan, Garrido‐Laguna, Ignacio, Cannon, George M.

“…BACKGROUND The role of chemoradiotherapy (CRT) in locally advanced pancreatic cancer (LAPC) is uncertain after multiple randomized clinical trials have yielded…”
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From state-of-the-art treatments to novel therapies for advanced-stage pancreatic cancer by Nevala-Plagemann, Christopher, Hidalgo, Manuel, Garrido-Laguna, Ignacio

“…Improvements in the outcomes of patients with pancreatic ductal adenocarcinoma (PDAC) have lagged behind advances made in the treatment of many other…”
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Cancer-Associated Adipocytes Exhibit an Activated Phenotype and Contribute to Breast Cancer Invasion by DIRAT, Béatrice, BOCHET, Ludivine, GARRIDO, Ignacio, ESCOURROU, Ghislaine, VALET, Philippe, MULLET, Catherine, DABEK, Marta, DAVIAUD, Danièle, DAUVILLIER, Stephanie, MAJED, Bilal, YUAN YUAN WANG, MEULLE, Aline, SALLES, Bernard, LE GONIDEC, Sophie

“…Early local tumor invasion in breast cancer results in a likely encounter between cancer cells and mature adipocytes, but the role of these fat cells in tumor…”
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The Importance of the Tumor Microenvironment to Understand Tumor Origin, Evolution, and Treatment Response by Ayuso, Jose M, Ochoa Garrido, Ignacio

“…During the second half of the twentieth century, oncology adopted a tumor-centric approach to cancer treatment, focusing primarily on the tumor cell to…”
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Advanced technological tools to study multidrug resistance in cancer by Andrei, Luca, Kasas, Sandor, Ochoa Garrido, Ignacio, Stanković, Tijana, Suárez Korsnes, Mónica, Vaclavikova, Radka, Assaraf, Yehuda G., Pešić, Milica

“…The complexity of cancer biology and its clinical manifestation are driven by genetic, epigenetic, transcriptomic, proteomic and metabolomic alterations,…”
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First‐in‐human, phase I study of PF‐06647263, an anti‐EFNA4 calicheamicin antibody–drug conjugate, in patients with advanced solid tumors by Garrido‐Laguna, Ignacio, Krop, Ian, Burris, Howard A., Hamilton, Erika, Braiteh, Fadi, Weise, Amy M., Abu‐Khalaf, Maysa, Werner, Theresa L., Pirie‐Shepherd, Steven, Zopf, Christopher J., Lakshminarayanan, Mani, Holland, Jaymes S., Baffa, Raffaele, Hong, David S.

“…PF‐06647263, a novel antibody–drug conjugate consisting of an anti‐EFNA4 antibody linked to a calicheamicin payload, has shown potent antitumor activity in…”
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Fall classification, incidence and circumstances in patients undergoing total knee replacement by Blasco, José-María, Pérez-Maletzki, José, Díaz-Díaz, Beatriz, Silvestre-Muñoz, Antonio, Martínez-Garrido, Ignacio, Roig-Casasús, Sergio

“…The objective was to propose a fall-classification framework for patients undergoing total knee replacement (TKR). In addition, we reinforced the available…”
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Spatial and temporal stability in the genetic structure of a marine crab despite a biogeographic break by Veliz, David, Rojas-Hernández, Noemi, Vega-Retter, Caren, Zaviezo, Camila, Garrido, Ignacio, Pardo, Luis Miguel

“…Elucidating the processes responsible for maintaining the population connectivity of marine benthic species mediated by larval dispersal remains a fundamental…”
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Clinical Development of Anti-TIGIT Antibodies for Immunotherapy of Cancer by Florou, Vaia, Garrido-Laguna, Ignacio

“…Purpose of Review T-cell immunoglobulin and ITIM domain (TIGIT) is a next-generation inhibitory receptor with multiple antibodies under exploration in cancer…”
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High endothelial venules (HEVs) in human melanoma lesions: Major gateways for tumor-infiltrating lymphocytes by Martinet, Ludovic, Le Guellec, Sophie, Filleron, Thomas, Lamant, Laurence, Meyer, Nicolas, Rochaix, Philippe, Garrido, Ignacio, Girard, Jean-Philippe

“…The presence of tumor-infiltrating lymphocytes (TILs) is a strong prognostic parameter for local dissemination and overall survival in melanoma. Lymphocyte…”
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A Phase I, First‐in‐Human Study of GSK2849330, an Anti‐HER3 Monoclonal Antibody, in HER3‐Expressing Solid Tumors by Gan, Hui K., Millward, Michael, Jalving, Mathilde, Garrido‐Laguna, Ignacio, Lickliter, Jason D., Schellens, Jan H.M., Lolkema, Martijn P., Van Herpen, Carla L.M., Hug, Bruce, Tang, Lihua, O'Connor‐Semmes, Robin, Gagnon, Robert, Ellis, Catherine, Ganji, Gopinath, Matheny, Christopher, Drilon, Alexander

“…Background GSK2849330, an anti‐HER3 monoclonal antibody that blocks HER3/Neuregulin 1 (NRG1) signaling in cancer cells, is engineered for enhanced…”
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Transcriptomic responses of Antarctic clam Laternula elliptica to nanoparticles, at single and combined exposures reveal ecologically relevant biomarkers by Rondon, Rodolfo, Valdés, Catalina, Cosseau, Céline, Bergami, Elisa, Cárdenas, César Antonio, Balbi, Teresa, Pérez-Toledo, Carolina, Garrido, Ignacio, Perrois, Garance, Chaparro, Cristian, Corre, Erwan, Corsi, Ilaria, González-Aravena, Marcelo

“…In recent years micro- and nanoplastics and metal-oxide nanomaterials have been found in several environmental compartments. The Antarctic soft clam Laternula…”
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Mechanically Isolated Stromal Vascular Fraction Provides a Valid and Useful Collagenase-Free Alternative Technique: A Comparative Study by Chaput, Benoit, Bertheuil, Nicolas, Escubes, Marina, Grolleau, Jean-Louis, Garrido, Ignacio, Laloze, Jérôme, Espagnolle, Nicolas, Casteilla, Louis, Sensebé, Luc, Varin, Audrey

“…BACKGROUND:The use of stromal vascular fraction and adipose-derived stromal cells in tissue regeneration is now being increasingly investigated, and studies…”
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Consistent Richness-Biomass Relationship across Environmental Gradients in a Marine Macroalgal-Dominated Subtidal Community on the Western Antarctic Peninsula by Valdivia, Nelson, Díaz, María José, Garrido, Ignacio, Gómez, Iván

“…Biodiversity loss has spurred the biodiversity-ecosystem functioning research over a range of ecosystems. In Antarctica, however, the relationship of taxonomic…”
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Metabolomics Study of Human Urinary Metabolome Modifications After Intake of Almond (Prunus dulcis (Mill.) D.A. Webb) Skin Polyphenols by Llorach, Rafael, Garrido, Ignacio, Monagas, María, Urpi-Sarda, Mireia, Tulipani, Sara, Bartolome, Begoña, Andres-Lacueva, Cristina

“…Almond, as a part of the nut family, is an important source of biological compounds, and specifically, almond skins have been considered an important source of…”
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Up, down, and all around: scale-dependent spatial variation in rocky-shore communities of Fildes Peninsula, King George Island, Antarctica by Valdivia, Nelson, Díaz, María J, Holtheuer, Jorge, Garrido, Ignacio, Huovinen, Pirjo, Gómez, Iván

“…Understanding the variation of biodiversity along environmental gradients and multiple spatial scales is relevant for theoretical and management purposes…”
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The effects of preoperative balance training on balance and functional outcome after total knee replacement: a randomized controlled trial by Blasco, José-María, Acosta-Ballester, Yolanda, Martínez-Garrido, Ignacio, García-Molina, Pablo, Igual-Camacho, Celedonia, Roig-Casasús, Sergio

“…Objective: To assess the effects of preoperative balance training on the early postoperative balance and functional outcomes after total knee replacement…”
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Metastatic Pancreatic Cancer: ASCO Guideline Update by Sohal, Davendra P.S., Kennedy, Erin B., Cinar, Pelin, Conroy, Thierry, Copur, Mehmet S., Crane, Christopher H., Garrido-Laguna, Ignacio, Lau, Michelle W., Johnson, Tyler, Krishnamurthi, Smitha, Moravek, Cassadie, O’Reilly, Eileen M., Philip, Philip A., Pant, Shubham, Shah, Manish A., Sahai, Vaibhav, Uronis, Hope E., Zaidi, Neeha, Laheru, Daniel

“…PURPOSEThe aim of this work was to provide an update to the ASCO guideline on metastatic pancreatic cancer pertaining to recommendations for therapy options…”
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