Search Results - "GAROVOY, M. R"

HLA class II antigen associations help to define two types of alopecia areata by COLOMBE, B. W, PRICE, V. H, KHOURY, E. L, GAROVOY, M. R, LOU, C. D

“…Multiple HLA class I and class II antigen associations have been described for alopecia areata (AA). As in other immune-mediated diseases, the HLA antigens…”
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Population pharmacokinetics and pharmacodynamics of the anti-CD11a antibody hu1124 in human subjects with psoriasis by Bauer, R J, Dedrick, R L, White, M L, Murray, M J, Garovoy, M R

“…The pharmacokinetics of hu1124, a human anti-CD11a antibody, were investigated in human subjects with psoriasis. CD11a is a subunit of LFA-1, a cell surface…”
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A Novel Targeted T-Cell Modulator, Efalizumab, for Plaque Psoriasis by Lebwohl, Mark, Tyring, Stephen K, Hamilton, Tiffani K, Toth, Darryl, Glazer, Scott, Tawfik, Naji H, Walicke, Patricia, Dummer, Wolfgang, Wang, Xiaolin, Garovoy, Marvin R, Pariser, David

“…Leukocyte-function–associated antigen type 1 (LFA-1) is involved in the pathogenesis of psoriasis. Efalizumab is a humanized monoclonal antibody that binds to…”
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Thrombin stimulates c-sis gene expression in microvascular endothelial cells by Daniel, T O, Gibbs, V C, Milfay, D F, Garovoy, M R, Williams, L T

“…We have determined whether expression of the c-sis gene product, platelet-derived growth factor (PDGF), is regulated in cultured renal microvascular…”
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Successful immunomodulation with intravenous gamma globulin and cyclophosphamide in an alloimmunized heart transplant recipient by De Marco, T, Damon, L E, Colombe, B, Keith, F, Chatterjee, K, Garovoy, M R

“…A highly human leukocyte antigen-sensitized heart transplant candidate underwent immunomodulation with intravenous gamma globulin and cyclophosphamide. His…”
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Effect of food on the pharmacokinetics of cyclosporine in healthy subjects following oral and intravenous administration by Gupta, S K, Manfro, R C, Tomlanovich, S J, Gambertoglio, J G, Garovoy, M R, Benet, L Z

“…The pharmacokinetics of cyclosporine were studied in healthy subjects following administration of cyclosporine both orally (10 mg kg-1) and intravenously (4 mg…”
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IL-4 inhibits IL-2 receptor expression and IL-2-dependent proliferation of human T cells by Martinez, OM, Gibbons, RS, Garovoy, MR, Aronson, FR

“…Recent studies have shown that IL-4 can affect lymphocyte responses to IL-2. To evaluate the effects of IL-4 on T cell responses to physiologically relevant…”
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Direct evidence for in vivo induction of CD8+ cytotoxic T cells directed to donor MHC class I peptides following mouse allotransplantation by Popov, I A, Fedoseyeva, E V, Orr, P L, Garovoy, M R, Benichou, G

“…There is accumulating evidence indicating that the T cell response to donor major histocompatibility complex (MHC) peptides plays a crucial role in graft…”
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Characteristics of Oligonucleotide Uptake in Human Keratinocyte Cultures by Noonberg, Sarah B, Garovoy, Marvin R, Hunt, C Anthony

“…Oligodeoxyribonucleotides have the potential to interfere selectivity with cellular protein synthesis by sequence-specific hybridization to DNA or RNA…”
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Cytokine and T cell receptor gene expression at the site of allograft rejection by Krams, S M, Falco, D A, Villanueva, J C, Rabkin, J, Tomlanovich, S J, Vincenti, F, Amend, W J, Melzer, J, Garovoy, M R, Roberts, J P

“…Intragraft cytokine and T cell receptor gene expression was analyzed in rejecting renal allografts by polymerase chain reaction (PCR). Message for IL-1 beta,…”
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Flow cytometry crossmatching as a predictor of acute rejection in sensitized recipients of cadaveric renal transplants by O'rourke, Robert W, Osorio, Robert W, Freise, Chris E, Lou, Calvin D, Garovoy, Marvin R, Bacchetti, Peter, Ascher, Nancy L, Melzer, Juliet S, Roberts, John P, Stock, Peter G

“…Flow cytometry crossmatching (FCXM) was developed as a more sensitive assay than the standard complement‐dependent cytotoxicity crossmatch (CDCXM) for the…”
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The use of intravenous immunoglobulin in recurrent pregnancy loss associated with combined alloimmune and autoimmune abnormalities by Kiprov, D D, Nachtigall, R D, Weaver, R C, Jacobson, A, Main, E K, Garovoy, M R

“…Several studies have evaluated the effect of intravenous gammaglobulin (IVIG) in women with unexplained recurrent spontaneous abortions (RSA). Data regarding…”
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Identification of high- and low-risk second kidney grafts by MAHONEY, R. J, NORMAN, D. J, COLOMBE, B. W, GAROVOY, M. R, LEEBER, D. A

“…The purpose of this study was to identify recipients who are at low or high risk of early cadaveric regraft failure by segregating results of the flow…”
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Induction of T cell responses to a self-antigen following allotransplantation by FEDOSEYEVA, E. V, TAM, R. C, POPOV, I. A, ORR, P. L, GAROVOY, M. R, BENICHOU, G

“…T cell tolerance to self-antigens is established through the recognition by immature T cells of dominant self-peptides presented in association with self-MHC…”
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The treatment of moderate to severe psoriasis with a new anti-CD11a monoclonal antibody by Papp, Kim, Bissonnette, Robert, Krueger, James G., Carey, Wayne, Gratton, David, Gulliver, Wayne P., Lui, Harvey, Lynde, Charles W., Magee, Anna, Minier, Daniel, Ouellet, Jean P., Patel, Piyush, Shapiro, Jerry, Shear, Neil H., Kramer, Susan, Walicke, Patricia, Bauer, Robert, Dedrick, Russell L., Kim, Sun Sook, White, Mark, Garovoy, Marvin R.

“…Background: Anti-CD11a (hu1124) is a humanized monoclonal antibody directed against the CD11a subunit of LFA-1. This study investigated whether treatment with…”
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Type I diabetes mellitus in monozygotic twins: chronic progressive beta cell dysfunction by Srikanta, S, Ganda, O P, Jackson, R A, Gleason, R E, Kaldany, A, Garovoy, M R, Milford, E L, Carpenter, C B, Soeldner, J S, Eisenbarth, G S

“…In a prospective 21-year study, islet cell antibodies and beta cell function were serially assessed in 24 monozygotic twins initially discordant for type I…”
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An oligonucleotide blocks interferon-γ signal transduction by LEE, P. P, RAMANATHAN, M, HUNT, C. A, GAROVOY, M. R

“…Interferon (IFN)-gamma is an important mediator of transplant graft rejection. It induces endothelial cell expression of HLA-DR and intercellular adhesion…”
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Sequence-Independent Inhibition of RNA Transcription by DNA Dumbbells and Other Decoys by Lim, Carol S., Jabrane-Ferrat, Nabila, Fontes, Joseph D., Okamoto, Hiroshi, Garovoy, Marvin R., Peterlin, B. Matija, Anthony Hunt, C.

“…DNA dumbbells are stable, short segments of double-stranded DNA with closed nucleotide loops on each end, conferring resistance to exonucleases. Dumbbells may…”
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Inhibition of interferon-gamma-induced major histocompatibility complex class I expression by certain oligodeoxynucleotides by Ramanathan, M, Lantz, M, MacGregor, R D, Huey, B, Tam, S, Li, Y, Garovoy, M R, Hunt, C A

“…We report that certain oligonucleotides are capable of inhibiting cell surface induction of the major histocompatibility complex class I (MHC-I) proteins by…”
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Associations of HLA-DR and HLA-DQ types with anti-GBM nephritis by sequence-specific oligonucleotide probe hybridization by Huey, Bing, McCormick, Kelly, Capper, Jan, Ratliff, Christina, Colombe, Beth W., Garovoy, Marvin R., Wilson, Curtis B.

“…Associations of HLA-DR and HLA-DQ types with anti-GBM nephritis by sequence-specific oligonucleotide probe hybridization. Twenty-three patients from the United…”
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