Search Results - "GARIBOTTO, V"
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2020 update on the clinical validity of cerebrospinal fluid amyloid, tau, and phospho-tau as biomarkers for Alzheimer’s disease in the context of a structured 5-phase development framework
Published in European journal of nuclear medicine and molecular imaging (01-07-2021)“…Purpose In the last decade, the research community has focused on defining reliable biomarkers for the early detection of Alzheimer’s disease (AD) pathology…”
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The logopenic/phonological variant of primary progressive aphasia
Published in Neurology (14-10-2008)“…Primary progressive aphasia (PPA) is characterized by isolated decline in language functions. Semantic dementia and progressive nonfluent aphasia are accepted…”
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The validation status of blood biomarkers of amyloid and phospho-tau assessed with the 5-phase development framework for AD biomarkers
Published in European journal of nuclear medicine and molecular imaging (01-07-2021)“…Purpose The development of blood biomarkers that reflect Alzheimer’s disease (AD) pathophysiology (phosphorylated tau and amyloid-β) has offered potential as…”
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Clinical validity of increased cortical uptake of [18F]flortaucipir on PET as a biomarker for Alzheimer’s disease in the context of a structured 5-phase biomarker development framework
Published in European journal of nuclear medicine and molecular imaging (01-07-2021)“…Purpose In 2017, the Geneva Alzheimer’s disease (AD) Biomarker Roadmap initiative adapted the framework of the systematic validation of oncological diagnostic…”
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Resting-state functional connectivity abnormalities in subjective cognitive decline: A 7T MRI study
Published in Neurobiology of aging (01-12-2024)“…Resting-state functional connectivity (FC) MRI is sensitive to brain changes in Alzheimer’s disease in preclinical stages, however studies in persons with…”
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In vivo microglia activation in very early dementia with Lewy bodies, comparison with Parkinson's disease
Published in Parkinsonism & related disorders (01-01-2013)“…Abstract Background Reactive microgliosis, hallmark of neuroinflammation, may contribute to neuronal degeneration, as shown in several neurodegenerative…”
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Individual Detection of Patients with Parkinson Disease using Support Vector Machine Analysis of Diffusion Tensor Imaging Data: Initial Results
Published in American journal of neuroradiology : AJNR (01-12-2012)“…Brain MR imaging is routinely performed in the work-up of suspected PD, yet its role is essentially limited to the exclusion of other pathologies. We performed…”
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Disorganization of anatomical connectivity in obsessive compulsive disorder: A multi-parameter diffusion tensor imaging study in a subpopulation of patients
Published in Neurobiology of disease (01-02-2010)“…Abstract Obsessive–compulsive disorder (OCD) is thought to involve large-scale brain systems but the anatomical connectivity via association fibers has not…”
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Education and occupation as proxies for reserve in aMCI converters and AD FDG-PET evidence
Published in Neurology (21-10-2008)“…Previous reports have shown that higher education is associated with more severe brain pathology in patients with Alzheimer disease (AD), suggesting that these…”
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Dementia prevention in memory clinics: recommendations from the European task force for brain health services
Published in The Lancet regional health. Europe (01-03-2023)“…Observational population studies indicate that prevention of dementia and cognitive decline is being accomplished, possibly as an unintended result of better…”
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The strategic biomarker roadmap for the validation of Alzheimer’s diagnostic biomarkers: methodological update
Published in European journal of nuclear medicine and molecular imaging (01-07-2021)“…Background The 2017 Alzheimer’s disease (AD) Strategic Biomarker Roadmap (SBR) structured the validation of AD diagnostic biomarkers into 5 phases,…”
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A kinetics-based approach to amyloid PET semi-quantification
Published in European journal of nuclear medicine and molecular imaging (01-08-2020)“…Purpose To develop and validate a semi-quantification method (time-delayed ratio, TDr) applied to amyloid PET scans, based on tracer kinetics information…”
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Education and occupation provide reserve in both ApoE epsilon 4 carrier and noncarrier patients with probable Alzheimer's disease
Published in Neurological sciences (01-10-2012)“…According to the reserve hypothesis, a high educational/occupational attainment can modulate Alzheimer's disease (AD) clinical expression. The impact of the…”
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Education and occupation provide reserve in both ApoE ε4 carrier and noncarrier patients with probable Alzheimer’s disease
Published in Neurological sciences (01-10-2012)“…According to the reserve hypothesis, a high educational/occupational attainment can modulate Alzheimer’s disease (AD) clinical expression. The impact of the…”
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Impulse control disorder in PD: A lateralized monoaminergic frontostriatal disconnection syndrome?
Published in Parkinsonism & related disorders (01-09-2016)“…Abstract Background Impulse Control Disorder symptoms (ICD) in Parkinson's disease (PD) has been recently associated by magnetic Resonance imaging with…”
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Semi-quantification and grading of amyloid PET: a project of the European Alzheimer's Disease Consortium (EADC)
Published in NeuroImage clinical (01-01-2019)“…© 2019 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/BY-NC-ND/4.0/)…”
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Severe early basal ganglia hypometabolism in neurodegeneration with brain iron accumulation
Published in European journal of nuclear medicine and molecular imaging (01-08-2016)Get full text
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Source-Based Morphometry Multivariate Approach to Analyze [123I]FP-CIT SPECT Imaging
Published in Molecular imaging and biology (01-10-2017)“…Purpose [ 123 I]FP-CIT (DaTSCAN®) single-photon emission computed tomography (SPECT) imaging is widely used to study neurodegenerative parkinsonism, by…”
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Amyloid-PET and 18 F-FDG-PET in the diagnostic investigation of Alzheimer's disease and other dementias
Published in Lancet neurology (2020)“…Summary Various biomarkers are available to support the diagnosis of neurodegenerative diseases in clinical and research settings. Among the molecular imaging…”
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Nature versus nurture in frontotemporal lobar degeneration: the interaction of genetic background and education on brain damage
Published in Dementia and geriatric cognitive disorders (01-08-2012)“…Frontotemporal lobar degeneration (FTLD) is a progressive neurodegenerative disorder with a strong genetic background. It has been reported that modifiable…”
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