Search Results - "GARDNER, Richard L"
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Normal bias in the direction of fetal rotation depends on blastomere composition during early cleavage in the mouse
Published in PloS one (10-03-2010)“…Interest in establishing the basis of left/right asymmetry during embryogenesis has burgeoned in recent years. Relevant studies in mammals, focused largely on…”
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Embryonic stem cell-derived tissues are immunogenic but their inherent immune privilege promotes the induction of tolerance
Published in Proceedings of the National Academy of Sciences - PNAS (26-12-2007)“…Although human embryonic stem (ES) cells may one day provide a renewable source of tissues for cell replacement therapy (CRT), histoincompatibility remains a…”
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Imprinted X-inactivation in extra-embryonic endoderm cell lines from mouse blastocysts
Published in Development (Cambridge) (01-04-2005)“…The extra-embryonic endoderm lineage plays a major role in the nutritive support of the embryo and is required for several inductive events, such as anterior…”
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Inhibition of trophoblast stem cell potential in chorionic ectoderm coincides with occlusion of the ectoplacental cavity in the mouse
Published in Development (Cambridge) (01-08-2002)“…At the blastocyst stage of pre-implantation mouse development, close contact of polar trophectoderm with the inner cell mass (ICM) promotes proliferation of…”
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New cell lines from mouse epiblast share defining features with human embryonic stem cells
Published in Nature (12-07-2007)“…The application of human embryonic stem (ES) cells in medicine and biology has an inherent reliance on understanding the starting cell population. Human ES…”
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The basis and significance of pre–patterning in mammals
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (29-08-2003)“…The second polar body (Pb) provides an enduring marker of the animal pole of the zygote, thereby revealing that the axis of bilateral symmetry of the early…”
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Experimental analysis of the transdifferentiation of visceral to parietal endoderm in the mouse
Published in Developmental dynamics (01-07-2005)“…The visceral endoderm (VE) of isolated extraembryonic regions (ExEmbs) of 7 days postcoitum (dpc) prestreak mouse conceptuses have been shown to convert…”
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The Derivation of Highly Germline-Competent Embryonic Stem Cells Containing NOD-Derived Genome
Published in Diabetes (New York, N.Y.) (01-01-2003)“…The Derivation of Highly Germline-Competent Embryonic Stem Cells Containing NOD-Derived Genome Frances A. Brook 1 , Edward P. Evans 1 , Christopher J. Lord 2 ,…”
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On the fate of primordial germ cells injected into early mouse embryos
Published in Developmental biology (15-01-2014)“…Primordial germ cells (PGCs) are the founder cells of the germline. Via gametogenesis and fertilisation this lineage generates a new embryo in the next…”
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Stem cells and regenerative medicine: principles, prospects and problems
Published in Comptes rendus. Biologies (01-06-2007)“…Stem cells have been used routinely for more than three decades to repair tissues and organs damaged by injury or disease, most notably haematopoietic stem…”
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Bob Edwards and the first decade of Reproductive BioMedicine Online
Published in Reproductive biomedicine online (01-02-2011)Get full text
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The case for prepatterning in the mouse
Published in Birth defects research. Part C. Embryo today (01-06-2005)“…In studies from several laboratories using a variety of different techniques, features of the zygote and two‐cell conceptus have been found to map nonrandomly…”
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Application of alginate gels to the study of Mammalian development
Published in Methods in molecular biology (Clifton, N.J.) (2004)Get more information
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Human experimental chimaerism: Chimaeras as a source of stem cells
Published in Reproductive biomedicine online (01-09-2002)Get full text
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A structurally defined mini-chromosome vector for the mouse germ line
Published in Current biology (13-01-2000)“…Yeast artificial mini-chromosomes have helped to define the features of chromosome architecture important for accurate segregation and replication [1] and have…”
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Contributions of blastocyst micromanipulation to the study of mammalian development
Published in BioEssays (01-02-1998)“…This is a personal account of why the author chose to focus on devising techniques for micromanipulating the blastocyst stage conceptus as a way of…”
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Trophectoderm growth and bilateral symmetry of the blastocyst in the mouse
Published in Human reproduction (Oxford) (01-07-2002)“…BACKGROUND: The present study was undertaken to ascertain whether the polarized flow of cells from polar to mural trophectoderm is related to the axis of…”
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Assessing Strategies for Control of Irrigation-Induced Salinity in the Upper Colorado River Basin
Published in American journal of agricultural economics (01-02-1988)“…Dissolved mineral salts (salinity) adversely affects numerous urban and agricultural users of Colorado River water in southwestern United States and in Mexico…”
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Polarity in early mammalian development
Published in Current opinion in genetics & development (01-08-1999)“…Although overall polarity is discernable morphologically in both the growing and mature oocyte in mammals, it is typically relatively inconspicuous in the…”
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