Search Results - "GARCIA SAINZ, J. A"

Effects of arachidonic acid on FFA4 receptor: Signaling, phosphorylation and internalization by Villegas-Comonfort, S, Takei, Y, Tsujimoto, G, Hirasawa, A, García-Sáinz, J.A

“…Abstract Arachidonic acid increased intracellular calcium, in cells expressing green fluorescent protein-tagged human FFA4 receptors, with an EC50 of ~ 40 µM…”
Get full text

Assembly and sealing of tight junctions : possible participation of G-proteins, phospholipase C, protein kinase C and calmodulin by BALDA, M. S, GONZALEZ-MARSICAL, L, CONTRERAS, R. G, MACIAS-SILVA, M, TORRES-MARQUEZ, M. E, GARCIA SAINZ, J. A, CEREIJIDO, M

“…The making and sealing of a tight junction (TJ) requires cell-cell contacts and Ca2+, and can be gauged through the development of transepithelial electrical…”
Get full text

Characterization of the AT1 angiotensin II receptor expressed in guinea pig liver by García-Sáinz, J A, Martínez-Alfaro, M, Romero-Avila, M T, González-Espinosa, C

“…In guinea pig hepatocytes angiotensin II induced phosphorylase a activation. This effect was mimicked by other angiotensins with the potency order: angiotensin…”
Get more information

Hepatocyte beta-adrenergic responsiveness and guanine nucleotide-binding regulatory proteins by García-Sáinz, J A, Huerta-Bahena, M E, Malbon, C C

“…Hepatocytes isolated from hypothyroid, adrenalectomized, or partially hepatectomized rats display an enhanced beta-adrenergic responsiveness as compared with…”
Get full text

The GTP-binding protein of rod outer segments. II. An essential role for Mg2+ in signal amplification by Yamazaki, A, Bitensky, M W, Garcia-Sainz, J A

“…The role of Mg2+ in the GTP hydrolytic cycle was investigated by using purified subunits (G alpha and G beta, gamma) of the GTP-binding protein isolated from…”
Get full text

Pertussis toxin prevents homologous desensitization of adenylate cyclase in cultured renal epithelial cells by Wilson, P D, Dixon, B S, Dillingham, M A, Garcia-Sainz, J A, Anderson, R J

“…The biochemical mechanisms of adenylate cyclase desensitization in arginine vasopressin-responsive epithelial cells remain unclear. Preincubation of cultured…”
Get full text

Activated protein kinase C binds to intracellular receptors in rat hepatocytes by ROBLES-FLORES, M, GARCIA-SAINZ, J. A

“…The aim of this study was to identify in rat hepatocytes cellular polypeptides that bind protein kinase C (PKC) and may influence its activity and its…”
Get full text

D2-dopamine receptor-mediated inhibition of cyclic AMP formation in striatal neurons in primary culture by Weiss, S, Sebben, M, Garcia-Sainz, J A, Bockaert, J

“…Dopamine (DA) regulation of intracellular cyclic AMP formation in purified, intact striatal neurons in primary culture was examined. DA (EC50, 3 microM) and…”
Get more information

Modulation of Gs activity by phorbol myristate acetate in rat hepatocytes by Hernández-Sotomayor, S M, Macías-Silva, M, Malbon, C C, García-Sáinz, J A

“…Activation of protein kinase C promotes heterologous desensitization of hepatic adenylate cyclase. The basis for this desensitization was explored by use of a…”
Get full text

Hormonal stimulation of mitochondrial glutaminase. Effects of vasopressin, angiotensin II, adrenaline and glucagon by Corvera, S, García-Sáinz, J A

“…Adrenaline (through alpha 1-adrenoceptors), vasopressin and angiotensin II stimulate mitochondrial glutaminase activity. This stimulation probably contributes…”
Get full text

Stimulatory action of cycloheximide on glucose metabolism in the rat epididymal fat pad by García-Sáinz, J A, Piña, E, Chagoya de Sánchez, V

“…The action of cycloheximide on some parameters of glucose and lipid metabolism was studied in vitro in epidiymal fat pads from fasted rats. Incubation of fat…”
Get full text

Correlation between phosphatidylinositol labeling and contraction in rabbit aorta: effect of alpha-1 adrenergic activation by Villalobos-Molina, R, Uc, M, Hong, E, García-Sáinz, J A

“…Activation of rabbit aortic strips with alpha adrenergic agonists increased the labeling (with [32P]Pi) of phosphatidylinositol (PI) and phosphatidic acid and…”
Get more information

Homologous beta-adrenergic desensitization in isolated rat hepatocytes by García-Sáinz, J A, Michel, B

“…Hepatocytes from hypothyroid rats have a marked beta-adrenergic responsiveness. Preincubation of these hepatocytes with isoprenaline induced a time-dependent…”
Get full text

Effect of phorbol esters on the hormonal responsiveness of isolated white fat cells by García-Sáinz, J A, Juárez-Ayala, J

“…Phorbol 12-myristate 13-acetate (PMA) did not alter the basal cyclic AMP accumulation or lipolysis in isolated rat fat cells. Similarly, PMA was unable to…”
Get more information

Guanine nucleotide-induced positive cooperativity in muscarinic-cholinergic antagonist binding by Boyer, J L, Martínez-Cárcamo, M, Monroy-Sánchez, J A, Posadas, C, García-Sáinz, J A

“…The effect of guanine nucleotides on the binding of [3H] Quinuclidinyl benzilate to heart muscarinic receptors was studied. It was observed that GTP and Gpp…”
Get more information

Effects of adenosine on liver cell damage induced by carbon tetrachloride by Hernández-Muñoz, R, Glender, W, Díaz Muñoz, M, Adolfo, J, García-Sáinz, J A, Chagoya de Sánchez, V

“…Adenosine administration delayed the fatty liver and cell necrosis induced by carbon tetrachloride without affecting the action of the hepatotoxin on protein…”
Get more information

Cross-talk between glucagon- and adenosine-mediated signalling systems in rat hepatocytes: effects on cyclic AMP-phosphodiesterase activity by Robles-Flores, M, Allende, G, Piña, E, García-Sáinz, J A

“…The effect of adenosine analogues on glucagon-stimulated cyclic AMP accumulation in rat hepatocytes was explored. N6-Cyclopentyladenosine (CPA),…”
Get full text

Angiotensin II stimulates phosphoinositide turnover and phosphorylase through AII-1 receptors in isolated rat hepatocytes by García-Sáinz, J A, Macías-Silva, M

“…Angiotensin II stimulated the activity of phosphorylase a (EC50 approximately 3 nM). The effect of two receptor subtype-selective nonpeptide antagonists, DuP…”
Get more information

Effect of pertussis toxin on hormonal responsiveness of rat hepatocytes by Pushpendran, Choliparambil K., Corvera, Silvia, Adolfo García-Sáinz, J.

“…The ureogenic action of epinephrine in hepatocytes from normal adult rats is mediated through activation of α 1-adrenoceptors. β-Adrenoceptors in addition to α…”
Get full text

Angiotensin AT1 receptors in clone 9 rat liver cells : Ca2+ signaling and c-fos expression by GARCIA-SAINZ, J. A, GARCIA-CABALLERO, A, GONZALEZ-ESPINOSA, C

“…In C9 (Clone 9) liver cells, angiotensin 11 increased the intracellular Ca2+ content, inositol phosphate production and c-fos mRNA expression. Other…”
Get full text