Search Results - "GARCIA RODRIGUEZ, Luis A"
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Low-Dose Aspirin for the Prevention of Atherothrombosis
Published in The New England journal of medicine (01-12-2005)“…This review considers the role of low-dose aspirin for the prevention of atherothrombosis, discussing the molecular mechanism of action of aspirin as well as…”
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Antihypertensive drugs and risk of incident gout among patients with hypertension: population based case-control study
Published in BMJ (12-01-2012)“…Objective To determine the independent associations of antihypertensive drugs with the risk of incident gout among people with hypertension.Design Nested…”
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3
Mortality after hemorrhagic stroke: Data from general practice (The Health Improvement Network)
Published in Neurology (06-08-2013)“…OBJECTIVE:To investigate short-term case fatality and long-term mortality after intracerebral hemorrhage (ICH) and subarachnoid hemorrhage (SAH) using data…”
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4
Statins and Risk of Diabetes: An analysis of electronic medical records to evaluate possible bias due to differential survival
Published in Diabetes care (01-05-2013)“…Two meta-analyses of randomized trials of statins found increased risk of type 2 diabetes. One possible explanation is bias due to differential survival when…”
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New use of low-dose aspirin and risk of colorectal cancer by stage at diagnosis: a nested case-control study in UK general practice
Published in BMC cancer (07-09-2017)“…Evidence from clinical trial populations suggests low-dose aspirin reduces the risk of colorectal cancer (CRC). Part of this reduction in risk might be due to…”
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Confounding adjustment via a semi-automated high-dimensional propensity score algorithm: an application to electronic medical records
Published in Pharmacoepidemiology and drug safety (01-08-2011)“…ABSTRACT Purpose A semi‐automated high‐dimensional propensity score (hd‐PS) algorithm has been proposed to adjust for confounding in claims databases. The…”
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Cardioprotective aspirin users and their excess risk of upper gastrointestinal complications
Published in BMC medicine (20-09-2006)“…To balance the cardiovascular benefits from low-dose aspirin against the gastrointestinal harm caused, studies have considered the coronary heart disease risk…”
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Effect of Antisecretory Drugs and Nitrates on the Risk of Ulcer Bleeding Associated With Nonsteroidal Anti-Inflammatory Drugs, Antiplatelet Agents, and Anticoagulants
Published in The American journal of gastroenterology (01-03-2007)“…After the withdrawal of some cyclooxygenase-2 (COX-2) selective inhibitors, traditional nonsteroidal anti-inflammatory drug (NSAID) use has increased, but…”
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Validation of low-dose aspirin prescription data in The Health Improvement Network: how much misclassification due to over-the-counter use?
Published in Pharmacoepidemiology and drug safety (01-04-2016)“…Purpose We aimed to quantify the extent of over‐the‐counter (OTC) low‐dose aspirin use among patients in The Health Improvement Network (THIN) in the UK…”
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Study of the Association Between Hip Fracture and Acid-Suppressive Drug Use in a UK Primary Care Setting
Published in Pharmacotherapy (01-06-2014)“…Objectives We aimed to clarify the nature of the association between hip fracture risk and use of proton pump inhibitors (PPIs) or histamine2‐receptor…”
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Systematic review of peptic ulcer disease incidence rates: do studies without validation provide reliable estimates?
Published in Pharmacoepidemiology and drug safety (01-07-2011)“…ABSTRACT Purpose Incidence rate (IR) estimates for peptic ulcer disease (PUD) vary widely among studies. We conducted a systematic review to quantify and…”
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Validity and completeness of colorectal cancer diagnoses in a primary care database in the United Kingdom
Published in Pharmacoepidemiology and drug safety (01-04-2016)“…Purpose To validate the recorded diagnoses of colorectal cancer (CRC) and identify false negatives in The Health Improvement Network (THIN) primary care…”
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Analyzing partially missing confounder information in comparative effectiveness and safety research of therapeutics
Published in Pharmacoepidemiology and drug safety (01-05-2012)“…ABSTRACT Purpose Electronic healthcare databases are commonly used in comparative effectiveness and safety research of therapeutics. Many databases now include…”
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14
Non‐Steroidal Antiinflammatory Drugs and the Risk of Acute Myocardial Infarction
Published in Basic & clinical pharmacology & toxicology (01-03-2006)“…: Whether non‐aspirin non‐steroidal antiinflammatory drugs (NSAIDs) affect the risk of myocardial infarction is unclear. Also, it is unknown whether the effect…”
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Journal Article Conference Proceeding -
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Gastroesophageal reflux disease in children and adolescents in primary care
Published in Scandinavian journal of gastroenterology (01-01-2010)“…Abstract Objectives. To determine the prevalence and incidence of a diagnosis of gastroesophageal reflux disease (GERD) in children and adolescents in UK…”
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Risk of Complications After a Peptic Ulcer Diagnosis: Effectiveness of Proton Pump Inhibitors
Published in Digestive diseases and sciences (01-06-2013)“…Background Few studies have evaluated the prevention of upper gastrointestinal complications (UGIC; bleeding or perforation) in patients with uncomplicated…”
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Do case-only designs yield consistent results across design and different databases? A case study of hip fractures and benzodiazepines
Published in Pharmacoepidemiology and drug safety (01-03-2016)“…Background The case‐crossover (CXO) and self‐controlled case series (SCCS) designs are increasingly used in pharmacoepidemiology. In both, relative risk…”
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Risk of bleeding after hospitalization for a serious coronary event: a retrospective cohort study with nested case-control analyses
Published in BMC cardiovascular disorders (30-08-2016)“…Bleeding events have been associated with the use of antiplatelet agents. This study estimated the incidence of bleeding events in patients previously…”
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Relationship between gastroesophageal reflux disease and COPD in UK primary care
Published in Chest (01-12-2008)“…Gastroesophageal reflux symptoms may be more common in patients with COPD than in control subjects. The aim of this study was to investigate the relationship…”
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Mortality in patients who discontinue low‐dose acetylsalicylic acid therapy after upper gastrointestinal bleeding
Published in Pharmacoepidemiology and drug safety (01-02-2017)“…Purpose Discontinuing low‐dose acetylsalicylic acid (ASA) therapy after upper gastrointestinal bleeding (UGIB) may increase the risk of cardiovascular‐related…”
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