Search Results - "GARCIA BONILLA, Lidia"

Factors secreted by endothelial progenitor cells enhance neurorepair responses after cerebral ischemia in mice by Rosell, Anna, Morancho, Anna, Navarro-Sobrino, Miriam, Martínez-Saez, Elena, Hernández-Guillamon, Mar, Lope-Piedrafita, Silvia, Barceló, Verónica, Borrás, Francesc, Penalba, Anna, García-Bonilla, Lidia, Montaner, Joan

“…Cell therapy with endothelial progenitor cells (EPCs) has emerged as a promising strategy to regenerate the brain after stroke. Here, we aimed to investigate…”
Get full text

VAP-1/SSAO plasma activity and brain expression in human hemorrhagic stroke by Hernandez-Guillamon, Mar, Solé, Montse, Delgado, Pilar, García-Bonilla, Lidia, Giralt, Dolors, Boada, Cristina, Penalba, Anna, García, Sandra, Flores, Alan, Ribó, Marc, Alvarez-Sabin, José, Ortega-Aznar, Arantxa, Unzeta, Mercedes, Montaner, Joan

“…Vascular adhesion protein-1 (VAP-1) is a cell surface and circulating enzyme that belongs to the semicarbazide-sensitive amine oxidase (SSAO) family, which…”
Get more information

Brain Perivascular Macrophages Initiate the Neurovascular Dysfunction of Alzheimer Aβ Peptides by Park, Laibaik, Uekawa, Ken, Garcia-Bonilla, Lidia, Koizumi, Kenzo, Murphy, Michelle, Pistik, Rose, Younkin, Linda, Younkin, Steven, Zhou, Ping, Carlson, George, Anrather, Josef, Iadecola, Costantino

“…Increasing evidence indicates that alterations of the cerebral microcirculation may play a role in Alzheimer disease, the leading cause of late-life dementia…”
Get full text

Endothelium-Macrophage Crosstalk Mediates Blood-Brain Barrier Dysfunction in Hypertension by Santisteban, Monica M., Ahn, Sung Ji, Lane, Diane, Faraco, Giuseppe, Garcia-Bonilla, Lidia, Racchumi, Gianfranco, Poon, Carrie, Schaeffer, Samantha, Segarra, Steven G., Körbelin, Jakob, Anrather, Josef, Iadecola, Costantino

“…Hypertension is a leading cause of stroke and dementia, effects attributed to disrupting delivery of blood flow to the brain. Hypertension also alters the…”
Get full text

The role of microglia and myeloid immune cells in acute cerebral ischemia by Benakis, Corinne, Garcia-Bonilla, Lidia, Iadecola, Costantino, Anrather, Josef

“…The immune response to acute cerebral ischemia is a major contributor to stroke pathobiology. The inflammatory response is characterized by the participation…”
Get full text

Proteomic characterization of protein phosphatase 1 complexes in ischemia-reperfusion and ischemic tolerance by Cid, Cristina, Garcia-Bonilla, Lidia, Camafeita, Emilio, Burda, Jozef, Salinas, Matilde, Alcazar, Alberto

“…Serine/threonine protein phosphatase 1 (PP1) regulates multiple cellular processes. Protein phosphorylation-dephosphorylation is largely altered during…”
Get full text

Inducible nitric oxide synthase in neutrophils and endothelium contributes to ischemic brain injury in mice by Garcia-Bonilla, Lidia, Moore, Jamie M, Racchumi, Gianfranco, Zhou, Ping, Butler, Jason M, Iadecola, Costantino, Anrather, Josef

“…NO produced by inducible NO synthase (iNOS) contributes to ischemic brain injury, but the cell types expressing iNOS and mediating tissue damage have not been…”
Get full text

Metalloproteinase and stroke infarct size: role for anti-inflammatory treatment? by Morancho, Anna, Rosell, Anna, García-Bonilla, Lidia, Montaner, Joan

“…Deregulation of matrix metalloproteinases (MMPs), the largest class of human proteases, has been implicated in brain damage in both animal and human studies…”
Get full text

Progranulin deficiency promotes post-ischemic blood-brain barrier disruption by Jackman, Katherine, Kahles, Timo, Lane, Diane, Garcia-Bonilla, Lidia, Abe, Takato, Capone, Carmen, Hochrainer, Karin, Voss, Henning, Zhou, Ping, Ding, Aihao, Anrather, Josef, Iadecola, Costantino

“…Loss-of-function mutations of progranulin (PGRN) have been linked to frontotemporal dementia, but little is known about the effects of PGRN deficiency on the…”
Get full text

Citicoline in pre-clinical animal models of stroke: a meta-analysis shows the optimal neuroprotective profile and the missing steps for jumping into a stroke clinical trial by Bustamante, Alejandro, Giralt, Dolors, Garcia-Bonilla, Lidia, Campos, Mireia, Rosell, Anna, Montaner, Joan

“…The neuroprotective actions of citicoline have been documented for experimental stroke therapy. We used a systematic review and meta‐analysis to assess this…”
Get full text

Commentary on Myers et al.: Growing role of the innate immunity receptor CD36 in central nervous system diseases by Garcia-Bonilla, Lidia, Park, Laibaik, Iadecola, Costantino

“…Activation of innate immunity by sterile inflammation has emerged as a key event in selected CNS diseases, with a defining impact on all stages of the…”
Get full text

Evidence for the efficacy of statins in animal stroke models: a meta-analysis by García-Bonilla, Lidia, Campos, Mireia, Giralt, Dolors, Salat, David, Chacón, Pilar, Hernández-Guillamon, Mar, Rosell, Anna, Montaner, Joan

“…J. Neurochem. (2012) 122, 233–243. Protective effects of statins have been well documented for stroke therapy. Here, we used a systematic review and…”
Get full text

Role of protein synthesis in the ischemic tolerance acquisition induced by transient forebrain ischemia in the rat by BURDA, Jozef, HREHOROVSKA, Milina, GARCIA BONILLA, Lidia, DANIELISOVA, Viera, CIZKOVA, Dasa, BURDA, Rastislav, NEMETHOVA, Miroslava, FANDO, Juan L, SALINAS, Matilde

“…Although ischemic preconditioning of the heart and brain is a well-documented neuroprotective phenomenon, the mechanism underlying the increased resistance to…”
Get full text

Immune mechanisms in cerebral ischemic tolerance by Garcia-Bonilla, Lidia, Benakis, Corinne, Moore, Jamie, Iadecola, Costantino, Anrather, Josef

“…Stressor-induced tolerance is a central mechanism in the response of bacteria, plants, and animals to potentially harmful environmental challenges. This…”
Get full text

Activation-dependent substrate recruitment by the eukaryotic translation initiation factor 2 kinase PERK by Marciniak, Stefan J, Garcia-Bonilla, Lidia, Hu, Junjie, Harding, Heather P, Ron, David

“…Regulated phosphorylation of the [alpha] subunit of eukaryotic translation initiation factor 2 (eIF2[alpha]) by the endoplasmic reticulum (ER) stress-activated…”
Get full text

Effects of acute post-treatment with dipyridamole in a rat model of focal cerebral ischemia by García-Bonilla, Lidia, Sosti, Victoria, Campos, Mireia, Penalba, Anna, Boada, Cristina, Sumalla, Mireia, Hernández-Guillamon, Mar, Rosell, Anna, Montaner, Joan

“…Abstract Dipyridamole (DP) is a platelet inhibitor with known antithrombotic benefits in stroke prevention. In addition to its anti-aggregant properties,…”
Get full text

Brain proteomics identifies potential simvastatin targets in acute phase of stroke in a rat embolic model by Campos‐Martorell, Mireia, Salvador, Nelida, Monge, Marta, Canals, Francesc, García‐Bonilla, Lidia, Hernández‐Guillamon, Mar, Ayuso, María Irene, Chacón, Pilar, Rosell, Anna, Alcazar, Alberto, Montaner, Joan

“…Finding an efficient neuroprotectant is of urgent need in the field of stroke research. The goal of this study was to test the effect of acute simvastatin…”
Get full text

A new method for focal transient cerebral ischaemia by distal compression of the middle cerebral artery by Morancho, Anna, García-Bonilla, Lidia, Barceló, Verónica, Giralt, Dolors, Campos-Martorell, Mireia, Garcia, Sandra, Montaner, Joan, Rosell, Anna

“…A. Morancho, L. García‐Bonilla, V. Barceló, D. Giralt, M. Campos‐Martorell, S. Garcia, J. Montaner and A. Rosell (2012) Neuropathology and Applied…”
Get full text

Matrix metalloproteinase-13 is activated and is found in the nucleus of neural cells after cerebral ischemia by Cuadrado, Eloy, Rosell, Anna, Borrell-Pagès, Maria, García-Bonilla, Lidia, Hernández-Guillamon, Mar, Ortega-Aznar, Arantxa, Montaner, Joan

“…Matrix metalloproteinases (MMPs) have been implicated in the pathophysiology of ischemic stroke. In this study, we investigated the time course of…”
Get full text

Rat middle cerebral artery occlusion is not a suitable model for the study of stroke-induced spontaneous infections by Campos-Martorell, Mireia, Hernández-Guillamón, Mar, Rosell, Anna, Gomis, Javier, Salat, David, García-Bonilla, Lidia, Montaner, Joan

“…Infections related to stroke-induced immunodepression are an important complication causing a high rate of death in patients. Several experimental studies in…”
Get full text