Search Results - "GARCIA, Veronica E"

Genetic variants in FBN-1 and risk for thoracic aortic aneurysm and dissection by Iakoubova, Olga A, Tong, Carmen H, Rowland, Charles M, Luke, May M, Garcia, Veronica E, Catanese, Joseph J, Moomiaie, Remo M, Sotonyi, Peter, Ascady, Gyorgy, Nikas, Demitrios, Dedelias, Panagiotis, Tranquilli, Maryann, Elefteriades, John A

“…A recent genome wide association study (GWAS) by LeMaire et al. found that two single nucleotide polymorphisms (SNPs), rs2118181 and rs10519177 in the FBN-1…”
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A Large-Scale Genetic Association Study Confirms IL12B and Leads to the Identification of IL23R as Psoriasis-Risk Genes by Cargill, Michele, Schrodi, Steven J., Chang, Monica, Garcia, Veronica E., Brandon, Rhonda, Callis, Kristina P., Matsunami, Nori, Ardlie, Kristin G., Civello, Daniel, Catanese, Joseph J., Leong, Diane U., Panko, Jackie M., McAllister, Linda B., Hansen, Christopher B., Papenfuss, Jason, Prescott, Stephen M., White, Thomas J., Leppert, Mark F., Krueger, Gerald G., Begovich, Ann B.

“…We performed a multitiered, case-control association study of psoriasis in three independent sample sets of white North American individuals (1,446 cases and…”
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Elevated Cyclic AMP Inhibits Mycobacterium tuberculosis-Stimulated T-cell IFN-γ Secretion Through Type I Protein Kinase A by Chung, Yoon-tae, Pasquinelli, Virginia, Jurado, Javier O, Wang, Xisheng, Yi, Na, Barnes, Peter F, Garcia, Veronica E, Samten, Buka

“…Abstract Cyclic adenosine monophosphate (cAMP) is critical in immune regulation, and its role in tuberculosis infection remains unclear. We determined the…”
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A Missense Single-Nucleotide Polymorphism in a Gene Encoding a Protein Tyrosine Phosphatase ( PTPN22) Is Associated with Rheumatoid Arthritis by Begovich, Ann B., Carlton, Victoria E.H., Honigberg, Lee A., Schrodi, Steven J., Chokkalingam, Anand P., Alexander, Heather C., Ardlie, Kristin G., Huang, Qiqing, Smith, Ashley M., Spoerke, Jill M., Conn, Marion T., Chang, Monica, Chang, Sheng-Yung P., Saiki, Randall K., Catanese, Joseph J., Leong, Diane U., Garcia, Veronica E., McAllister, Linda B., Jeffery, Douglas A., Lee, Annette T., Batliwalla, Franak, Remmers, Elaine, Criswell, Lindsey A., Seldin, Michael F., Kastner, Daniel L., Amos, Christopher I., Sninsky, John J., Gregersen, Peter K.

“…Rheumatoid arthritis (RA) is the most common systemic autoimmune disease, affecting ∼1% of the adult population worldwide, with an estimated heritability of…”
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A large-scale rheumatoid arthritis genetic study identifies association at chromosome 9q33.2 by Chang, Monica, Rowland, Charles M, Garcia, Veronica E, Schrodi, Steven J, Catanese, Joseph J, van der Helm-van Mil, Annette H M, Ardlie, Kristin G, Amos, Christopher I, Criswell, Lindsey A, Kastner, Daniel L, Gregersen, Peter K, Kurreeman, Fina A S, Toes, Rene E M, Huizinga, Tom W J, Seldin, Michael F, Begovich, Ann B

“…Rheumatoid arthritis (RA) is a chronic, systemic autoimmune disease affecting both joints and extra-articular tissues. Although some genetic risk factors for…”
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Serine leucocyte proteinase inhibitor‐treated monocyte inhibits human CD4+ lymphocyte proliferation by Guerrieri, Diego, Tateosian, Nancy L., Maffía, Paulo C., Reiteri, Romina M., Amiano, Nicolás O., Costa, María J., Villalonga, Ximena, Sanchez, Mercedes L., Estein, Silvia M., Garcia, Verónica E., Sallenave, Jean‐Michel, Chuluyan, Héctor E.

“…Summary Serine leucocyte proteinase inhibitor (SLPI) is the main serine proteinase inhibitor produced by epithelial cells and has been shown to be a…”
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Secretory Leukocyte Protease Inhibitor: A Secreted Pattern Recognition Receptor for Mycobacteria by Gomez, Sonia A, Arguelles, Claudia L, Guerrieri, Diego, Tateosian, Nancy L, Amiano, Nicolas O, Slimovich, Rut, Maffia, Paulo C, Abbate, Eduardo, Musella, Rosa M, Garcia, Veronica E, Chuluyan, H. Eduardo

“…Human secretory leukocyte protease inhibitor (SLPI) displays bactericidal activity against pathogens such as Escherichia coli and Streptococcus. Furthermore,…”
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The Impact of IFN-γ Receptor on SLPI Expression in Active Tuberculosis by Tateosian, Nancy L, Pasquinelli, Virginia, Hernández Del Pino, Rodrigo E, Ambrosi, Nella, Guerrieri, Diego, Pedraza-Sánchez, Sigifredo, Santucci, Natalia, D’Attilio, Luciano, Pellegrini, Joaquín, Araujo-Solis, María A, Musella, Rosa M, Palmero, Domingo J, Hernandez-Pando, Rogelio, Garcia, Verónica E, Chuluyan, H. Eduardo

“…Interferon (IFN)-γ displays a critical role in tuberculosis (TB), modulating the innate and adaptive immune responses. Previously, we reported that secretory…”
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Neutrophil Elastase Converts Human Immature Dendritic Cells into Transforming Growth Factor-β1-Secreting Cells and Reduces Allostimulatory Ability by Maffia, Paulo César, Zittermann, Sandra Elizabeth, Scimone, María Lucila, Tateosian, Nancy, Amiano, Nicolás, Guerrieri, Diego, Lutzky, Viviana, Rosso, Diego, Romeo, Horacio Eduardo, Garcia, Verónica E, Issekutz, Andrew C, Chuluyan, H. Eduardo

“…During microbial infection, neutrophils (polymorphonuclear leukocytes; PMNs) activate dendritic cells (DCs). However, early reports illustrated that…”
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Programmed Death (PD)-1:PD-Ligand 1/PD-Ligand 2 Pathway Inhibits T Cell Effector Functions during Human Tuberculosis by Jurado, Javier O, Alvarez, Ivana B, Pasquinelli, Virginia, Martinez, Gustavo J, Quiroga, Maria F, Abbate, Eduardo, Musella, Rosa M, Chuluyan, H. Eduardo, Garcia, Veronica E

“…Protective immunity against Mycobacterium tuberculosis requires the generation of cell-mediated immunity. We investigated the expression and role of programmed…”
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Pairwise linkage disequilibrium under disease models by SCHRODI, Steven J, GARCIA, Veronica E, ROWLAND, Charley, JONES, Hywel B

“…Many genetic studies of disease association rely heavily on linkage disequilibrium (LD) patterns between pairs of markers to detect susceptibility markers…”
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Role Played by the Programmed Death-1-Programmed Death Ligand Pathway during Innate Immunity against Mycobacterium tuberculosis by Alvarez, Ivana B., Pasquinelli, Virginia, Jurado, Javier O., Abbate, Eduardo, Musella, Rosa M., de la Barrera, Silvia S., García, Verónica E.

“…Tuberculous pleurisy allows the study of specific cells at the site of Mycobacterium tuberculosis infection. Among pleural lymphocytes, natural killer (NK)…”
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IL-17 and IFN-γ expression in lymphocytes from patients with active tuberculosis correlates with the severity of the disease by Jurado, Javier O., Pasquinelli, Virginia, Alvarez, Ivana B., Peña, Delfina, Rovetta, Ana I., Tateosian, Nancy L., Romeo, Horacio E., Musella, Rosa M., Palmero, Domingo, Chuluyán, H. Eduardo, García, Verónica E.

“…Mycobacterium tuberculosis expands CD4+IFN‐γ+IL‐17+ lymphocytes in direct correlation with the severity of active disease. Th1 lymphocytes are crucial in the…”
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IFNG-mediated immune responses enhance autophagy against Mycobacterium tuberculosis antigens in patients with active tuberculosis by Rovetta, Ana I, Peña, Delfina, Hernández Del Pino, Rodrigo E, Recalde, Gabriela M, Pellegrini, Joaquín, Bigi, Fabiana, Musella, Rosa M, Palmero, Domingo J, Gutierrez, Marisa, Colombo, María I, García, Verónica E

“…Protective immunity against Mycobacterium tuberculosis (Mtb) requires IFNG. Besides, IFNG-mediated induction of autophagy suppresses survival of virulent Mtb…”
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IFN-γ and IgG responses to Mycobacterium tuberculosis latency antigen Rv2626c differentiate remote from recent tuberculosis infection by Amiano, Nicolás O., Morelli, María P., Pellegrini, Joaquín M., Tateosian, Nancy L., Rolandelli, Agustín, Seery, Vanesa, Castello, Florencia A., Gallego, Claudio, Armitano, Rita, Stupka, Juan, Erschen, María A., Ciallella, Lorena M., de Casado, Graciela C., Cusmano, Liliana, Palmero, Domingo J., Iovanna, Juan L., García, Verónica E.

“…Tuberculin skin test (TST) and IFN-γ release assays are currently used to detect Mycobacterium tuberculosis ( Mtb ) infection but none of them differentiate…”
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Mannose-capped lipoarabinomannan- and prostaglandin E2-dependent expansion of regulatory T cells in human Mycobacterium tuberculosis infection by Garg, Ankita, Barnes, Peter F, Roy, Sugata, Quiroga, María F, Wu, Shiping, García, Verónica E, Krutzik, Stephan R, Weis, Steven E, Vankayalapati, Ramakrishna

“…We evaluated the role of regulatory T cells (CD4⁺ CD25⁺ Foxp3⁺ cells, Tregs) in human Mycobacterium tuberculosis infection. Tregs were expanded in response to…”
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Circulating Monocyte-Like Myeloid Derived Suppressor Cells and CD16 Positive Monocytes Correlate With Immunological Responsiveness of Tuberculosis Patients by Amiano, Nicolás O, Pellegrini, Joaquín M, Morelli, María P, Martinena, Camila, Rolandelli, Agustín, Castello, Florencia A, Casco, Nicolás, Ciallella, Lorena M, de Casado, Graciela C, Armitano, Rita, Stupka, Juan, Gallego, Claudio, Palmero, Domingo J, García, Verónica E, Tateosian, Nancy L

“…Alterations of myeloid cell populations have been reported in patients with tuberculosis (TB). In this work, we studied the relationship between…”
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Restimulation‐induced T‐cell death through NTB‐A/SAP signaling pathway is impaired in tuberculosis patients with depressed immune responses by Hernández Del Pino, Rodrigo E, Pellegrini, Joaquín M, Rovetta, Ana I, Peña, Delfina, Álvarez, Guadalupe I, Rolandelli, Agustín, Musella, Rosa M, Palmero, Domingo J, Malbran, Alejandro, Pasquinelli, Virginia, García, Verónica E

“…Production of IFN‐γ contributes to host defense against Mycobacterium tuberculosis (Mtb) infection. We previously demonstrated that Signaling lymphocytic…”
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Phosphorylation of Mitogen-Activated Protein Kinases Contributes to Interferon γ Production in Response to Mycobacterium tuberculosis by Pasquinelli, Virginia, Rovetta, Ana I., Alvarez, Ivana B., Jurado, Javier O., Musella, Rosa M., Palmero, Domingo J., Malbrán, Alejandro, Samten, Buka, Barnes, Peter F., García, Verónica E.

“…Immune control of Mycobacterium tuberculosis depends on interferon γ (IFN-γ)-producing CD4⁺ lymphocytes. Previous studies have shown that T cells from patients…”
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The impact of IFN-γ receptor on SLPI expression in active tuberculosis: association with disease severity by Tateosian, Nancy L, Pasquinelli, Virginia, Hernández Del Pino, Rodrigo E, Ambrosi, Nella, Guerrieri, Diego, Pedraza-Sánchez, Sigifredo, Santucci, Natalia, D'Attilio, Luciano, Pellegrini, Joaquín, Araujo-Solis, María A, Musella, Rosa M, Palmero, Domingo J, Hernandez-Pando, Rogelio, Garcia, Verónica E, Chuluyan, H Eduardo

“…Interferon (IFN)-γ displays a critical role in tuberculosis (TB), modulating the innate and adaptive immune responses. Previously, we reported that secretory…”
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