Search Results - "GARAICOECHEA, Lorena"
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Recombinant monovalent llama-derived antibody fragments (VHH) to rotavirus VP6 protect neonatal gnotobiotic piglets against human rotavirus-induced diarrhea
Published in PLoS pathogens (01-05-2013)“…Group A Rotavirus (RVA) is the leading cause of severe diarrhea in children. The aims of the present study were to determine the neutralizing activity of…”
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2
Anti-hemagglutinin monomeric nanobody provides prophylactic immunity against H1 subtype influenza A viruses
Published in PloS one (10-07-2024)“…Influenza viruses constitute a major threat to human health globally. The viral surface glycoprotein hemagglutinin (HA) is the immunodominant antigen, contains…”
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3
Anti-VP6 VHH: An Experimental Treatment for Rotavirus A-Associated Disease
Published in PloS one (07-09-2016)“…Species A Rotaviruses (RVA) remain a leading cause of mortality in children under 5 years of age. Current treatment options are limited. We assessed the…”
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4
Are Human P[14] Rotavirus Strains the Result of Interspecies Transmissions from Sheep or Other Ungulates That Belong to the Mammalian Order Artiodactyla?
Published in Journal of Virology (01-04-2009)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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5
Llama nanoantibodies with therapeutic potential against human norovirus diarrhea
Published in PloS one (12-08-2015)“…Noroviruses are a major cause of acute gastroenteritis, but no vaccines or therapeutic drugs are available. Llama-derived single chain antibody fragments (also…”
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6
Llama-Derived Single-Chain Antibody Fragments Directed to Rotavirus VP6 Protein Possess Broad Neutralizing Activity In Vitro and Confer Protection against Diarrhea in Mice
Published in Journal of Virology (01-10-2008)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Discovery and molecular characterization of a group A rotavirus strain detected in an Argentinean vicuña (Vicugna vicugna)
Published in Veterinary microbiology (25-01-2013)“…The wild vicuña (Vicugna vicugna) is one of the four species of native South American camelids (SACs) in addition to the wild guanaco, and their domesticated…”
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Molecular characterization of equine rotaviruses circulating in Argentinean foals during a 17-year surveillance period (1992–2008)
Published in Veterinary microbiology (24-03-2011)“…P[12]G3 and P[12]G14 equine rotaviruses (ERVs) are epidemiologically important in horses. In Argentina, the prevalent ERV strains have been historically…”
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9
Rotavirus A-specific single-domain antibodies produced in baculovirus-infected insect larvae are protective in vivo
Published in BMC biotechnology (07-09-2012)“…Single-domain antibodies (sdAbs), also known as nanobodies or VHHs, are characterized by high stability and solubility, thus maintaining the affinity and…”
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10
Evolutionarily conserved regulators of tau identify targets for new therapies
Published in Neuron (Cambridge, Mass.) (15-03-2023)“…Tauopathies are neurodegenerative diseases that involve the pathological accumulation of tau proteins; in this family are Alzheimer disease, corticobasal…”
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11
Anti-hemagglutinin monomeric nanobody provides prophylactic immunity against H1 subtype influenza A viruses
Published in PloS one (01-01-2024)Get full text
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12
Complete molecular genome analyses of equine rotavirus A strains from different continents reveal several novel genotypes and a largely conserved genotype constellation
Published in Journal of general virology (01-04-2012)“…In this study, the complete genome sequences of seven equine group A rotavirus (RVA) strains (RVA/Horse-tc/GBR/L338/1991/G13P[18],…”
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13
Translational fusion and redirection to thylakoid lumen as strategies to improve the accumulation of a camelid antibody fragment in transplastomic tobacco
Published in Planta (01-08-2012)“…Fragments from camelid single-chain antibodies known as VHHs or nanobodies represent a valuable tool in diagnostics, investigation and passive immunity…”
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14
Controlling Rotavirus-associated diarrhea: Could single-domain antibody fragments make the difference?
Published in Revista argentina de microbiología (01-10-2015)“…Group A Rotavirus (RVA) remains a leading cause of severe diarrhea and child mortality. The variable domain of camelid heavy chain antibodies (VHH) display…”
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15
Recombinant Monovalent Llama-Derived Antibody Fragments (VHH) to Rotavirus VP6 Protect Neonatal Gnotobiotic Piglets against Human Rotavirus-Induced Diarrhea: e1003334
Published in PLoS pathogens (01-05-2013)“…Group A Rotavirus (RVA) is the leading cause of severe diarrhea in children. The aims of the present study were to determine the neutralizing activity of…”
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Journal Article -
16
Llama Nanoantibodies with Therapeutic Potential against Human Norovirus Diarrhea: e0133665
Published in PloS one (01-08-2015)“…Noroviruses are a major cause of acute gastroenteritis, but no vaccines or therapeutic drugs are available. Llama-derived single chain antibody fragments (also…”
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17
Validation of an indirect ELISA to detect antibodies against BoHV-1 in bovine and guinea-pig serum samples using ISO/IEC 17025 standards
Published in Journal of virological methods (01-10-2010)“…Two ELISAs to quantify antibodies to BoHV-1 in the sera of cattle and immunized guinea pigs were developed and validated using ISO/IEC 17025 standards. The…”
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18
Lactogenic immunity: Modulation of immune response and protection against RV diarrhea in a calf model
Published in Veterinary immunology and immunopathology (15-03-2009)Get full text
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