Search Results - "GARABALINO, Marcela A"
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Therapeutic efficacy of boron neutron capture therapy mediated by boron-rich liposomes for oral cancer in the hamster cheek pouch model
Published in Proceedings of the National Academy of Sciences - PNAS (11-11-2014)“…The application of boron neutron capture therapy (BNCT) mediated by liposomes containing ¹⁰B-enriched polyhedral borane and carborane derivatives for the…”
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Cobaltabis(Dicarbollide) [ o -COSAN] - for Boron Neutron Capture Therapy of Head and Neck Cancer: Biodistribution and Irradiation Studies in an Experimental Oral Cancer Model
Published in Pharmaceuticals (Basel, Switzerland) (01-10-2024)“…Boron neutron capture therapy (BNCT) is a tumor-selective particle radiotherapy that combines preferential boron accumulation in tumors and neutron…”
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Therapeutic Efficacy, Radiotoxicity and Abscopal Effect of BNCT at the RA-3 Nuclear Reactor Employing Oligo-Fucoidan and Glutamine as Adjuvants in an Ectopic Colon Cancer Model in Rats
Published in Life (Basel, Switzerland) (01-07-2023)“…Boron neutron capture therapy (BNCT) is based on the preferential uptake of B compounds by tumors, followed by neutron irradiation. The aim of this study was…”
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Translational boron neutron capture therapy (BNCT) studies for the treatment of tumors in lung
Published in International journal of radiation biology (01-05-2019)“…Purpose: Boron neutron capture therapy (BNCT) combines selective accumulation of 10 B carriers in tumor tissue with subsequent neutron irradiation. BNCT has…”
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Clinical Veterinary Boron Neutron Capture Therapy (BNCT) Studies in Dogs with Head and Neck Cancer: Bridging the Gap between Translational and Clinical Studies
Published in Biology (Basel, Switzerland) (01-10-2020)“…Translational Boron Neutron Capture Therapy (BNCT) studies performed by our group and clinical BNCT studies worldwide have shown the therapeutic efficacy of…”
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Enhancement in the Therapeutic Efficacy of In Vivo BNCT Mediated by GB-10 with Electroporation in a Model of Oral Cancer
Published in Cells (Basel, Switzerland) (25-04-2023)“…Boron neutron capture therapy (BNCT) combines preferential tumor uptake of B compounds and neutron irradiation. Electroporation induces an increase in the…”
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Boron Neutron Capture Therapy (BNCT) Mediated by Maleimide-Functionalized Closo-Dodecaborate Albumin Conjugates (MID:BSA) for Oral Cancer: Biodistribution Studies and In Vivo BNCT in the Hamster Cheek Pouch Oral Cancer Model
Published in Life (Basel, Switzerland) (20-07-2022)“…Background: BNCT (Boron Neutron Capture Therapy) is a tumor-selective particle radiotherapy that combines preferential boron accumulation in tumors and neutron…”
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Abscopal effect of boron neutron capture therapy (BNCT): proof of principle in an experimental model of colon cancer
Published in Radiation and environmental biophysics (01-11-2017)“…The aim of the present study was to evaluate, for the first time, the abscopal effect of boron neutron capture therapy (BNCT). Twenty-six BDIX rats were…”
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Tumor Blood Vessel “Normalization” Improves the Therapeutic Efficacy of Boron Neutron Capture Therapy (BNCT) in Experimental Oral Cancer
Published in Radiation research (01-01-2012)“…We previously demonstrated the efficacy of BNCT mediated by boronophenylalanine (BPA) to treat tumors in a hamster cheek pouch model of oral cancer with no…”
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“Sequential” Boron Neutron Capture Therapy (BNCT): A Novel Approach to BNCT for the Treatment of Oral Cancer in the Hamster Cheek Pouch Model
Published in Radiation research (01-04-2011)“…In the present study the therapeutic effect and potential toxicity of the novel “Sequential” boron neutron capture therapy (Seq-BNCT) for the treatment of oral…”
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Boron neutron capture therapy (BNCT) for liver metastasis: therapeutic efficacy in an experimental model
Published in Radiation and environmental biophysics (01-08-2012)“…Boron neutron capture therapy (BNCT) was proposed for untreatable colorectal liver metastases. The present study evaluates tumor control and potential…”
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Blood Vessel Normalization in the Hamster Oral Cancer Model for Experimental Cancer Therapy Studies
Published in Anticancer research (01-07-2012)“…Normalization of tumor blood vessels improves drug and oxygen delivery to cancer cells. The aim of this study was to develop a technique to normalize blood…”
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Biodistribution of sodium borocaptate (BSH) for boron neutron capture therapy (BNCT) in an oral cancer model
Published in Radiation and environmental biophysics (01-08-2013)“…Boron neutron capture therapy (BNCT) is based on selective accumulation of 10 B carriers in tumor followed by neutron irradiation. We previously proved the…”
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Boron neutron capture therapy (BNCT) for the treatment of liver metastases: biodistribution studies of boron compounds in an experimental model
Published in Radiation and environmental biophysics (01-03-2011)“…We previously demonstrated the therapeutic efficacy of different boron neutron capture therapy (BNCT) protocols in an experimental model of oral cancer. BNCT…”
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Evaluation of local, regional and abscopal effects of Boron Neutron Capture Therapy (BNCT) combined with immunotherapy in an ectopic colon cancer model
Published in British journal of radiology (01-12-2021)“…The aim of the present study was to evaluate the local and regional therapeutic efficacy and abscopal effect of BNCT mediated by boronophenyl-alanine, combined…”
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Optimization of the classical oral cancerization protocol in hamster to study oral cancer therapy
Published in Oral diseases (01-09-2020)“…Objective(s) The hamster carcinogenesis model recapitulates oral oncogenesis. Dimethylbenz[a]anthracene (DMBA) cancerization induces early severe mucositis,…”
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Electroporation optimizes the uptake of boron-10 by tumor for boron neutron capture therapy (BNCT) mediated by GB-10: a boron biodistribution study in the hamster cheek pouch oral cancer model
Published in Radiation and environmental biophysics (01-08-2019)“…Boron neutron capture therapy (BNCT) is a promising cancer binary therapy modality that utilizes the nuclear capture reaction of thermal neutrons by boron-10…”
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Assessing advantages of sequential boron neutron capture therapy (BNCT) in an oral cancer model with normalized blood vessels
Published in Acta oncologica (01-01-2015)“…We previously demonstrated the therapeutic success of sequential boron neutron capture therapy (Seq-BNCT) in the hamster cheek pouch oral cancer model. It…”
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Different oral cancer scenarios to personalize targeted therapy: Boron Neutron Capture Therapy translational studies
Published in Therapeutic delivery (01-06-2019)“…Boron neutron capture therapy (BNCT) is a targeted therapy, which consists of preferential accumulation of boron carriers in tumor followed by neutron…”
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Boron neutron capture therapy (BNCT) translational studies in the hamster cheek pouch model of oral cancer at the new “B2” configuration of the RA-6 nuclear reactor
Published in Radiation and environmental biophysics (01-11-2017)“…Boron neutron capture therapy (BNCT) is based on selective accumulation of B-10 carriers in tumor followed by neutron irradiation. We demonstrated, in 2001,…”
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