Search Results - "GANTZ, Stephanie C"

The Evolving Understanding of Dopamine Neurons in the Substantia Nigra and Ventral Tegmental Area by Gantz, Stephanie C, Ford, Christopher P, Morikawa, Hitoshi, Williams, John T

“…In recent years, the population of neurons in the ventral tegmental area (VTA) and substantia nigra (SN) has been examined at multiple levels. The results…”
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Spontaneous Inhibitory Synaptic Currents Mediated by a G Protein-Coupled Receptor by Gantz, Stephanie C., Bunzow, James R., Williams, John T.

“…G protein-coupled receptors (GPCRs) affect many physiological processes by modulating both intrinsic membrane conductances and synaptic transmission. This…”
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Delta glutamate receptor conductance drives excitation of mouse dorsal raphe neurons by Gantz, Stephanie C, Moussawi, Khaled, Hake, Holly S

“…The dorsal raphe nucleus is the predominant source of central serotonin, where neuronal activity regulates complex emotional behaviors. Action potential firing…”
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Synaptic and intrinsic plasticity in the ventral tegmental area after chronic cocaine by Francis, Tanner Chase, Gantz, Stephanie C, Moussawi, Khaled, Bonci, Antonello

“…•Cocaine drives plasticity to enhance excitation of VTA dopamine neurons.•Dopamine release is decreased after chronic cocaine.•Neuromodulation therapies show…”
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Excitation of medium spiny neurons by 'inhibitory' ultrapotent chemogenetics via shifts in chloride reversal potential by Gantz, Stephanie C, Ortiz, Maria M, Belilos, Andrew J, Moussawi, Khaled

“…Ultrapotent chemogenetics, including the chloride-permeable inhibitory PSAM -GlyR receptor, were recently proposed as a powerful strategy to selectively…”
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Control of extracellular dopamine at dendrite and axon terminals by Ford, Christopher P, Gantz, Stephanie C, Phillips, Paul E M, Williams, John T

“…Midbrain dopamine neurons release dopamine from both axons and dendrites. The mechanism underlying release at these different sites has been proposed to…”
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rare DAT coding variant Val559 perturbs DA neuron function, changes behavior, and alters in vivo responses to psychostimulants by Mergy, Marc A, Gowrishankar, Raajaram, Gresch, Paul J, Gantz, Stephanie C, Williams, John, Davis, Gwynne L, Wheeler, C Austin, Stanwood, Gregg D, Hahn, Maureen K, Blakely, Randy D

“…Despite the critical role of the presynaptic dopamine (DA) transporter (DAT, SLC6A3 ) in DA clearance and psychostimulant responses, evidence that DAT…”
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Depression of Serotonin Synaptic Transmission by the Dopamine Precursor L-DOPA by Gantz, Stephanie C., Levitt, Erica S., Llamosas, Nerea, Neve, Kim A., Williams, John T.

“…Imbalance between the dopamine and serotonin (5-HT) neurotransmitter systems has been implicated in the comorbidity of Parkinson’s disease (PD) and psychiatric…”
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Loss of Mecp2 in substantia nigra dopamine neurons compromises the nigrostriatal pathway by Gantz, Stephanie C, Ford, Christopher P, Neve, Kim A, Williams, John T

“…Mutations in the methyl-CpG-binding protein 2 (MeCP2) result in Rett syndrome (RTT), an X-linked disorder that disrupts neurodevelopment. Girls with RTT…”
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Distinct regulation of dopamine D2S and D2L autoreceptor signaling by calcium by Gantz, Stephanie C, Robinson, Brooks G, Buck, David C, Bunzow, James R, Neve, Rachael L, Williams, John T, Neve, Kim A

“…D2 autoreceptors regulate dopamine release throughout the brain. Two isoforms of the D2 receptor, D2S and D2L, are expressed in midbrain dopamine neurons…”
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GluD receptors are functional ion channels by Kumar, Janesh, Popescu, Gabriela K., Gantz, Stephanie C.

“…In this article, we review contemporary evidence that GluD receptors are functional ion channels whose depolarizing currents contribute to their biological…”
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Potentiation of neuronal activity by tonic GluD1 current in brain slices by Copeland, Daniel S, Gugel, Aleigha, Gantz, Stephanie C

“…Ion channel function of native delta glutamate receptors (GluD R ) is incompletely understood. Previously, we and others have shown that activation of Gαq…”
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Cell-Autonomous Excitation of Midbrain Dopamine Neurons by Endocannabinoid-Dependent Lipid Signaling by Gantz, Stephanie C., Bean, Bruce P.

“…The major endocannabinoid in the mammalian brain is the bioactive lipid 2-arachidonoylglycerol (2-AG). The best-known effects of 2-AG are mediated by…”
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LC-derived excitatory synaptic transmission to dorsal raphe serotonin neurons is inhibited by activation of alpha2-adrenergic receptors by Gugel, Aleigha, Ingebretsen, Erik A, Hake, Holly S, Gantz, Stephanie C

“…In the central nervous system, noradrenaline transmission controls the degree to which we are awake, alert, and attentive. Aberrant noradrenaline transmission…”
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Deviating from the norm: cocaine-induced synaptic plasticity in the nucleus accumbens via σ1 receptors and endocannabinoid signaling by Copeland, Daniel S., Gantz, Stephanie C.

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Control of food approach and eating by a GABAergic projection from lateral hypothalamus to dorsal pons by Marino, Rosa Anna M., McDevitt, Ross A., Gantz, Stephanie C., Shen, Hui, Pignatelli, Marco, Xin, Wendy, Wise, Roy A., Bonci, Antonello

“…Electrical or optogenetic stimulation of lateral hypothalamic (LH) GABA neurons induces rapid vigorous eating in sated animals. The dopamine system has been…”
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Spatiotemporal Control of Noradrenaline-Dependent Synaptic Transmission in Mouse Dorsal Raphe Serotonin Neurons by Khamma, Jacqueline K, Copeland, Daniel S, Hake, Holly S, Gantz, Stephanie C

“…Activity of dorsal raphe neurons is controlled by noradrenaline afferents. In this brain region, noradrenaline activates Gα -coupled α1-adrenergic receptors…”
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Bidirectional flow of the funny current (If) during the pacemaking cycle in murine sinoatrial node myocytes by Peters, Colin H., Liu, Pin W., Morotti, Stefano, Gantz, Stephanie C., Grandi, Eleonora, Bean, Bruce P., Proenza, Catherine

“…Sinoatrial node myocytes (SAMs) act as cardiac pacemaker cells by firing spontaneous action potentials (APs) that initiate each heartbeat. The funny current…”
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Anti-angiogenic mechanisms and serotonergic dysfunction in the Rgs2 knockout model for the study of psycho-obstetric risk by Gumusoglu, Serena B, Kiel, Michaela D, Gugel, Aleigha, Schickling, Brandon M, Weaver, Kaylee R, Lauffer, Marisol C, Sullivan, Hannah R, Coulter, Kaylie J, Blaine, Brianna M, Kamal, Mushroor, Zhang, Yuping, Devor, Eric J, Santillan, Donna A, Gantz, Stephanie C, Santillan, Mark K

“…Psychiatric and obstetric diseases are growing threats to public health and share high rates of co-morbidity. G protein-coupled receptor signaling (e.g.,…”
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CRF Enhancement of GIRK Channel-Mediated Transmission in Dopamine Neurons by BECKSTEAD, Michael J, GANTZ, Stephanie C, FORD, Christopher P, STENZEL-POORE, Mary P, PHILLIPS, Paul E. M, MARK, Gregory P, WILLIAMS, John T

“…Dopamine neurons in the ventral midbrain contribute to learning and memory of natural and drug-related rewards. Corticotropin-releasing factor (CRF), a…”
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