Search Results - "GANGAPPA, Shivaprakash"

Influenza virus exploits tunneling nanotubes for cell-to-cell spread by Kumar, Amrita, Kim, Jin Hyang, Ranjan, Priya, Metcalfe, Maureen G., Cao, Weiping, Mishina, Margarita, Gangappa, Shivaprakash, Guo, Zhu, Boyden, Edward S., Zaki, Sherif, York, Ian, García-Sastre, Adolfo, Shaw, Michael, Sambhara, Suryaprakash

“…Tunneling nanotubes (TNTs) represent a novel route of intercellular communication. While previous work has shown that TNTs facilitate the exchange of viral or…”
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Role of Host Cytokine Responses in the Pathogenesis of Avian H5N1 Influenza Viruses in Mice by SZRETTER, Kristy J, GANGAPPA, Shivaprakash, XUIHUA LU, SMITH, Chalanda, SHIEH, Wun-Ju, ZAKI, Sherif R, SAMBHARA, Suryaprakash, TUMPEY, Terrence M, KATZ, Jacqueline M

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Protein Energy Malnutrition Decreases Immunity and Increases Susceptibility to Influenza Infection in Mice by Taylor, Andrew K., Cao, Weiping, Vora, Keyur P., De La Cruz, Juan, Shieh, Wun-Ju, Zaki, Sherif R., Katz, Jacqueline M., Sambhara, Suryaprakash, Gangappa, Shivaprakash

“…Background. Protein energy malnutrition (PEM), a common cause of secondary immune deficiency in children, is associated with an increased risk of infections…”
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Redirecting antibody responses from egg-adapted epitopes following repeat vaccination with recombinant or cell culture-based versus egg-based influenza vaccines by Liu, Feng, Gross, F. Liaini, Joshi, Sneha, Gaglani, Manjusha, Naleway, Allison L., Murthy, Kempapura, Groom, Holly C., Wesley, Meredith G., Edwards, Laura J., Grant, Lauren, Kim, Sara S., Sambhara, Suryaprakash, Gangappa, Shivaprakash, Tumpey, Terrence, Thompson, Mark G., Fry, Alicia M., Flannery, Brendan, Dawood, Fatimah S., Levine, Min Z.

“…Repeat vaccination with egg-based influenza vaccines could preferentially boost antibodies targeting the egg-adapted epitopes and reduce immunogenicity to…”
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Viral targeting of fibroblastic reticular cells contributes to immunosuppression and persistence during chronic infection by Mueller, Scott N, Matloubian, Mehrdad, Clemens, Daniel M, Sharpe, Arlene H, Freeman, Gordon J, Gangappa, Shivaprakash, Larsen, Christian P, Ahmed, Rafi

“…Many chronic viral infections are marked by pathogen persistence and a generalized immunosuppression. The exact mechanisms by which this occurs are still…”
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Quinazolin-derived myeloperoxidase inhibitor suppresses influenza A virus-induced reactive oxygen species, pro-inflammatory mediators and improves cell survival by De La Cruz, Juan A, Ganesh, Thota, Diebold, Becky A, Cao, Weiping, Hofstetter, Amelia, Singh, Neetu, Kumar, Amrita, McCoy, James, Ranjan, Priya, Smith, Susan M. E, Sambhara, Suryaprakash, Lambeth, J. David, Gangappa, Shivaprakash

“…Superoxide radicals and other reactive oxygen species (ROS) are implicated in influenza A virus-induced inflammation. In this in vitro study, we evaluated the…”
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Adenovirus vector-based multi-epitope vaccine provides partial protection against H5, H7, and H9 avian influenza viruses by Hassan, Ahmed O, Amen, Omar, Sayedahmed, Ekramy E, Vemula, Sai V, Amoah, Samuel, York, Ian, Gangappa, Shivaprakash, Sambhara, Suryaprakash, Mittal, Suresh K

“…The emergence of H5, H7, and H9 avian influenza virus subtypes in humans reveals their pandemic potential. Although human-to-human transmission has been…”
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Long-term survival of neonatal porcine islets in nonhuman primates by targeting costimulation pathways by Rajotte, Ray V, Larsen, Christian P, Cardona, Kenneth, Korbutt, Gregory S, Milas, Zvonimir, Lyon, James, Cano, Jose, Jiang, Wanhong, Bello-Laborn, Hameeda, Hacquoil, Brad, Strobert, Elizabeth, Gangappa, Shivaprakash, Weber, Collin J, Pearson, Thomas C

“…We evaluated the ability of neonatal porcine islets to engraft and restore glucose control in pancreatectomized rhesus macaques. Although porcine islets…”
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Immunogenicity of standard, high-dose, MF59-adjuvanted, and recombinant-HA seasonal influenza vaccination in older adults by Li, Athena P. Y., Cohen, Carolyn A., Leung, Nancy H. L., Fang, Vicky J., Gangappa, Shivaprakash, Sambhara, Suryaprakash, Levine, Min Z., Iuliano, A. Danielle, Perera, Ranawaka A. P. M., Ip, Dennis K. M., Peiris, J. S. Malik, Thompson, Mark G., Cowling, Benjamin J., Valkenburg, Sophie A.

“…The vaccine efficacy of standard-dose seasonal inactivated influenza vaccines (S-IIV) can be improved by the use of vaccines with higher antigen content or…”
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Early Control of H5N1 Influenza Virus Replication by the Type I Interferon Response in Mice by Szretter, Kristy J, Gangappa, Shivaprakash, Belser, Jessica A, Zeng, Hui, Chen, Hualan, Matsuoka, Yumiko, Sambhara, Suryaprakash, Swayne, David E, Tumpey, Terrence M, Katz, Jacqueline M

“…Widespread distribution of highly pathogenic avian H5N1 influenza viruses in domesticated and wild birds continues to pose a threat to public health, as…”
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NADPH Oxidase 1 Is Associated with Altered Host Survival and T Cell Phenotypes after Influenza A Virus Infection in Mice by Hofstetter, Amelia R, De La Cruz, Juan A, Cao, Weiping, Patel, Jenish, Belser, Jessica A, McCoy, James, Liepkalns, Justine S, Amoah, Samuel, Cheng, Guangjie, Ranjan, Priya, Diebold, Becky A, Shieh, Wun-Ju, Zaki, Sherif, Katz, Jacqueline M, Sambhara, Suryaprakash, Lambeth, J David, Gangappa, Shivaprakash

“…The role of the reactive oxygen species-producing NADPH oxidase family of enzymes in the pathology of influenza A virus infection remains enigmatic. Previous…”
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A Dual-Functioning 5ʹ-PPP-NS1shRNA that Activates a RIG-I Antiviral Pathway and Suppresses Influenza NS1 by Singh, Neetu, Ranjan, Priya, Cao, Weiping, Patel, Jenish, Gangappa, Shivaprakash, Davidson, Bruce A., Sullivan, John M., Prasad, Paras N., Knight, Paul R., Sambhara, Suryaprakash

“…Retinoic acid-inducible gene-I (RIG-I) is a cytosolic pathogen sensor that is crucial against a number of viral infections. Many viruses have evolved to…”
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The 3′ Untranslated Regions of Influenza Genomic Sequences Are 5′PPP-Independent Ligands for RIG-I by Davis, William G., Bowzard, J. Bradford, Sharma, Suresh D., Wiens, Mayim E., Ranjan, Priya, Gangappa, Shivaprakash, Stuchlik, Olga, Pohl, Jan, Donis, Ruben O., Katz, Jacqueline M., Cameron, Craig E., Fujita, Takashi, Sambhara, Suryaprakash

“…Retinoic acid inducible gene-I (RIG-I) is a key regulator of antiviral immunity. RIG-I is generally thought to be activated by ssRNA species containing a…”
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Influenza Virus Infects and Depletes Activated Adaptive Immune Responders by Bohannon, Caitlin D., Ende, Zachary, Cao, Weiping, Mboko, Wadzanai P., Ranjan, Priya, Kumar, Amrita, Mishina, Margarita, Amoah, Samuel, Gangappa, Shivaprakash, Mittal, Suresh K., Lovell, Jonathan F., García‐Sastre, Adolfo, Pfeifer, Blaine A., Davidson, Bruce A., Knight, Paul, Sambhara, Suryaprakash

“…Influenza infections cause several million cases of severe respiratory illness, hospitalizations, and hundreds of thousands of deaths globally. Secondary…”
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A Bovine Adenoviral Vector-Based H5N1 Influenza -Vaccine Provides Enhanced Immunogenicity and Protection at a Significantly Low Dose by Sayedahmed, Ekramy E., Hassan, Ahmed O., Kumari, Rashmi, Cao, Weiping, Gangappa, Shivaprakash, York, Ian, Sambhara, Suryaprakash, Mittal, Suresh K.

“…Several human and nonhuman adenovirus (AdV) vectors including bovine AdV type 3 (BAdV-3) were developed as gene delivery vectors to supplement and/or elude…”
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Nasal delivery of H5N1 avian influenza vaccine formulated with GenJet™ or in vivo-jetPEI® induces enhanced serological, cellular and protective immune responses by Cao, Weiping, Mishina, Margarita, Amoah, Samuel, Mboko, Wadzanai P., Bohannon, Caitlin, McCoy, James, Mittal, Suresh K., Gangappa, Shivaprakash, Sambhara, Suryaprakash

“…Avian influenza virus infection is a serious public health threat and preventive vaccination is the most cost-effective public health intervention strategy…”
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RIG-I activation inhibits ebolavirus replication by Spiropoulou, Christina F, Ranjan, Priya, Pearce, Melissa B, Sealy, Tara K, Albariño, César G, Gangappa, Shivaprakash, Fujita, Takashi, Rollin, Pierre E, Nichol, Stuart T, Ksiazek, Thomas G, Sambhara, Suryaprakash

“…Abstract Hemorrhagic fever viruses are associated with rapidly progressing severe disease with high case fatality, making them of public health and biothreat…”
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5'PPP-RNA induced RIG-I activation inhibits drug-resistant avian H5N1 as well as 1918 and 2009 pandemic influenza virus replication by Ranjan, Priya, Jayashankar, Lakshmi, Deyde, Varough, Zeng, Hui, Davis, William G, Pearce, Melissa B, Bowzard, John B, Hoelscher, Mary A, Jeisy-Scott, Victoria, Wiens, Mayim E, Gangappa, Shivaprakash, Gubareva, Larisa, García-Sastre, Adolfo, Katz, Jacqueline M, Tumpey, Terrence M, Fujita, Takashi, Sambhara, Suryaprakash

“…Emergence of drug-resistant strains of influenza viruses, including avian H5N1 with pandemic potential, 1918 and 2009 A/H1N1 pandemic viruses to currently used…”
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Identification of the in vivo role of a viral bcl-2 by Gangappa, Shivaprakash, van Dyk, Linda F, Jewett, Travis J, Speck, Samuel H, Virgin, 4th, Herbert W

“…Many gamma-herpesviruses encode candidate oncogenes including homologues of host bcl-2 and cyclin proteins (v-bcl-2, v-cyclin), but the physiologic roles of…”
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The 3' untranslated regions of influenza genomic sequences are 5'PPP-independent ligands for RIG-I by Davis, William G, Bowzard, J Bradford, Sharma, Suresh D, Wiens, Mayim E, Ranjan, Priya, Gangappa, Shivaprakash, Stuchlik, Olga, Pohl, Jan, Donis, Ruben O, Katz, Jacqueline M, Cameron, Craig E, Fujita, Takashi, Sambhara, Suryaprakash

“…Retinoic acid inducible gene-I (RIG-I) is a key regulator of antiviral immunity. RIG-I is generally thought to be activated by ssRNA species containing a…”
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