Search Results - "GALLENI, Moreno"
-
1
Highlighting the factors governing transglycosylation in the GH5_5 endo‐1,4‐β‐glucanase RBcel1
Published in Acta crystallographica. Section D, Biological crystallography. (01-03-2022)“…Transglycosylating glycoside hydrolases (GHs) offer great potential for the enzymatic synthesis of oligosaccharides. Although knowledge is progressing, there…”
Get full text
Journal Article -
2
Understanding the Significance and Implications of Antibody Numbering and Antigen-Binding Surface/Residue Definition
Published in Frontiers in immunology (16-10-2018)“…Monoclonal antibodies are playing an increasing role in both human and animal health. Different strategies of protein and chemical engineering, including…”
Get full text
Journal Article Web Resource -
3
Glycoside hydrolase family 5: structural snapshots highlighting the involvement of two conserved residues in catalysis
Published in Acta crystallographica. Section D, Biological crystallography. (01-02-2021)“…The ability of retaining glycoside hydrolases (GHs) to transglycosylate is inherent to the double‐displacement mechanism. Studying reaction intermediates, such…”
Get full text
Journal Article Web Resource -
4
RNA Regulatory Networks as a Control of Stochasticity in Biological Systems
Published in Frontiers in genetics (07-05-2019)“…The discovery that the non-protein coding part of human genome, dismissed as "junk DNA," is actively transcripted and carries out crucial functions is probably…”
Get full text
Journal Article -
5
Exploring the suitability of RanBP2-type Zinc Fingers for RNA-binding protein design
Published in Scientific reports (21-02-2019)“…Transcriptomes consist of several classes of RNA that have wide-ranging but often poorly described functions and the deregulation of which leads to numerous…”
Get full text
Journal Article Web Resource -
6
di-Cysteine Residues of the Arabidopsis thaliana HMA4 C-Terminus Are Only Partially Required for Cadmium Transport
Published in Frontiers in plant science (26-05-2020)“…Cadmium (Cd) is highly toxic to the environment and humans. Plants are capable of absorbing Cd from the soil and of transporting part of this Cd to their shoot…”
Get full text
Journal Article Web Resource -
7
Crystal structure determination of Pseudomonas stutzeri A1501 endoglucanase Cel5A: the search for a molecular basis for glycosynthesis in GH5_5 enzymes
Published in Acta crystallographica. Section D, Biological crystallography. (01-06-2019)“…The discovery of new glycoside hydrolases that can be utilized in the chemoenzymatic synthesis of carbohydrates has emerged as a promising approach for various…”
Get full text
Journal Article -
8
Exploring the Role of L10 Loop in New Delhi Metallo-β-lactamase (NDM-1): Kinetic and Dynamic Studies
Published in Molecules (Basel, Switzerland) (09-09-2021)“…Four NDM-1 mutants (L218T, L221T, L269H and L221T/Y229W) were generated in order to investigate the role of leucines positioned in L10 loop. A detailed kinetic…”
Get full text
Journal Article -
9
OXA-198, an Acquired Carbapenem-Hydrolyzing Class D β-Lactamase from Pseudomonas aeruginosa
Published in Antimicrobial Agents and Chemotherapy (01-10-2011)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text
Journal Article Web Resource -
10
1,2,4‐Triazole‐3‐Thione Analogues with a 2‐Ethylbenzoic Acid at Position 4 as VIM‐type Metallo‐β‐Lactamase Inhibitors
Published in ChemMedChem (05-04-2022)“…Metallo‐β‐lactamases (MBLs) are increasingly involved as a major mechanism of resistance to carbapenems in relevant opportunistic Gram‐negative pathogens…”
Get full text
Journal Article Web Resource -
11
Crystal structure and kinetic analysis of the class B3 di-zinc metallo-β-lactamase LRA-12 from an Alaskan soil metagenome
Published in PloS one (01-07-2017)“…We analyzed the kinetic properties of the metagenomic class B3 β-lactamase LRA-12, and determined its crystallographic structure in order to compare it with…”
Get full text
Journal Article Web Resource -
12
Conversion of Electrospun Chitosan into Chitin: A Robust Strategy to Tune the Properties of 2D Biomimetic Nanofiber Scaffolds
Published in Polysaccharides (01-06-2021)“…New biomimetic micro- and nano-CsU-based fibrous scaffolds electrospun from solution containing high purity-medical grade chitosan (CsU) of fungus origin…”
Get full text
Journal Article Web Resource -
13
Human Chitotriosidase: Catalytic Domain or Carbohydrate Binding Module, Who’s Leading HCHT’s Biological Function
Published in Scientific reports (05-06-2017)“…Chitin is an important structural component of numerous fungal pathogens and parasitic nematodes. The human macrophage chitotriosidase (HCHT) is a chitinase…”
Get full text
Journal Article Web Resource -
14
Der p 1 is the primary activator of Der p 3, Der p 6 and Der p 9 the proteolytic allergens produced by the house dust mite Dermatophagoides pteronyssinus
Published in Biochimica et biophysica acta (01-03-2014)“…The enzymatic activity of the four proteases found in the house dust mite Dermatophagoides pteronyssinus is involved in the pathogenesis of allergy. Our aim…”
Get full text
Journal Article Web Resource -
15
An Extended Reservoir of Class-D Beta-Lactamases in Non-Clinical Bacterial Strains
Published in Microbiology spectrum (27-04-2022)“…Bacterial genes coding for antibiotic resistance represent a major issue in the fight against bacterial pathogens. Among those, genes encoding beta-lactamases…”
Get full text
Journal Article Web Resource -
16
Seven-Year Evolution of β-Lactam Resistance Phenotypes in Escherichia coli Isolated from Young Diarrheic and Septicaemic Calves in Belgium
Published in Veterinary sciences (26-01-2022)“…Antimicrobial resistance is a major worldwide hazard. Therefore, the World Health Organization has proposed a classification of antimicrobials with respect to…”
Get full text
Journal Article Web Resource -
17
4-( N -Alkyl- and -Acyl-amino)-1,2,4-triazole-3-thione Analogs as Metallo-β-Lactamase Inhibitors: Impact of 4-Linker on Potency and Spectrum of Inhibition
Published in Biomolecules (Basel, Switzerland) (23-07-2020)“…To fight the increasingly worrying bacterial resistance to antibiotics, the discovery and development of new therapeutics is urgently needed. Here, we report…”
Get full text
Journal Article Web Resource -
18
A Pathway Closely Related to the d-Tagatose Pathway of Gram-Negative Enterobacteria Identified in the Gram-Positive Bacterium Bacillus licheniformis
Published in Applied and Environmental Microbiology (01-06-2013)“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text
Journal Article Web Resource -
19
Biochemical and Structural Characterization of the Subclass B1 Metallo-β-Lactamase VIM-4
Published in Antimicrobial Agents and Chemotherapy (01-03-2011)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text
Journal Article Web Resource -
20
Kinetic and Crystallographic Studies of Extended-Spectrum GES-11, GES-12, and GES-14 β-Lactamases
Published in Antimicrobial Agents and Chemotherapy (01-11-2012)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text
Journal Article Web Resource