Search Results - "GALENDO, D"
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Poly(ADP-ribose) polymerase-1 plays a role in suppressing mammary tumourigenesis in mice
Published in Oncogene (31-05-2007)“…The DNA strand break-binding molecule, poly(ADP-ribose) polymerase-1 (PARP-1), plays a role in DNA repair, chromosomal stability, transcription and cell death…”
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Cancer initiation by fumonisin B1 in rat liver - role of cell proliferation
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Heterozygous Men1 Mutant Mice Develop a Range of Endocrine Tumors Mimicking Multiple Endocrine Neoplasia Type 1
Published in Molecular endocrinology (Baltimore, Md.) (01-09-2003)“…Multiple endocrine neoplasia type 1 (MEN1) is a hereditary syndrome characterized by the occurrence of multiple endocrine tumors of the parathyroid, pancreas,…”
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Carcinogenicity study of the pesticide fenvalerate in mice
Published in Cancer letters (01-01-1990)“…Fenvalerate is a widely used pesticide, which has been shown recently to be nonmutagenic. We studied its carcinogenicity in a long-term experiment in inbred…”
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Carcinogenicity studies with deltamethrin in mice and rats
Published in Cancer letters (01-02-1990)“…The pesticide Deltamethrin, a synthetic pyrethroid, was studied for carcinogenicity in long-term experiments in mice and rats. Mice were given Deltamethrin by…”
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Transplacental induction of a specific mutation in fetal Ha-ras and its critical role in post-natal carcinogenesis
Published in International journal of cancer (15-12-1987)“…Mouse skin tumors were produced after transplacental initiation [with 7,12-dimethylbenz(a)anthracene], only when the skin was treated post-natally with a…”
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A carcinogenicity study of styrene-7,8-oxide in rats
Published in Cancer letters (01-08-1984)“…Styrene-7,8-oxide (200 mg/kg body wt) was given orally to female BDIV rats on 17th day of pregnancy. Their offspring received 96 weekly doses of styrene oxide…”
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Cancer initiation by fumonisin B 1 in rat liver – role of cell proliferation
Published in Cancer letters (28-08-2001)“…Fumonisin B 1 (FB 1), a carcinogenic mycotoxin produced by the fungus Fusarium verticillioides in corn, causes cancer initiation in rat liver in a similar…”
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Analytical method for the determination of sphinganine and sphingosine in serum as a potential biomarker for fumonisin exposure
Published in Journal of chromatography. B, Biomedical sciences and applications (11-12-1998)“…The toxins produced by Fusarium moniliforme, which include fumonisins, are possible human carcinogens. Fumonisins are inhibitors of de novo sphingolipid…”
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The induction and persistence of altered sphingolipid biosynthesis in rats treated with fumonisin B1
Published in Food additives and contaminants (01-09-2001)“…The fumonisins produced by Fusarium spp. are carcinogenic in rodents and possibly carcinogenic to humans. One action of fumonisins is to inhibit the enzyme…”
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UV-induced DNA damage and mutations in Hupki (human p53 knock-in) mice recapitulate p53 hotspot alterations in sun-exposed human skin
Published in Cancer research (Chicago, Ill.) (15-11-2001)“…The major etiological agent contributing to human nonmelanoma skin cancer is sunlight. The p53 tumor suppressor gene is usually mutated in these tumors, and…”
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Cancer initiation by fumonisin B(1) in rat liver--role of cell proliferation
Published in Cancer letters (28-08-2001)“…Fumonisin B(1) (FB(1)), a carcinogenic mycotoxin produced by the fungus Fusarium verticillioides in corn, causes cancer initiation in rat liver in a similar…”
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Evaluation of sister chromatid exchange as an indicator of sensitivity to N-ethyl-N-nitrosourea-induced carcinogenesis in rats
Published in Teratogenesis, carcinogenesis, and mutagenesis (1988)“…Sister chromatid exchange (SCE) frequencies in peripheral lymphocytes are a frequently used endpoint to indicate exposures to genotoxins in groups of humans…”
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Tissue-specific activating mutations of Ha- and Ki-ras oncogenes in skin, lung, and liver tumors induced in mice following transplacental exposure to DMBA
Published in Molecular carcinogenesis (1990)“…Transplacental carcinogenesis represents a good model in which to study the involvement of tissue-specific oncogene activation in carcinogenesis because a…”
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Absence of a synergistic effect between fumonisin B1 and N-nitrosomethylbenzylamine in the induction of oesophageal papillomas in the rat
Published in Natural toxins (1997)“…Fumonisins and N-nitrosamines (NNO) are suggested risk factors in the development of human oesophageal cancer; exposure to both occurs in high risk populations…”
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Activation of the Ha-ras oncogene in tumors induced in mice by transplacental exposure to 7,12-dimethylbenz(a)anthracene
Published in Voprosy onkologij (1991)“…A study of tumors induced in mice by transplacental exposure to 7,12-dimethylbenz(a)anthracene (DMBA) alone or in combination with postnatal tissue-specific…”
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Characterization and identification of 6 mutagens in opium pyrolysates implicated in oesophageal cancer in Iran
Published in Mutation research (01-06-1985)“…Previous epidemiological studies have indicated an association between the ingestion of opium pyrolysates, dietary deficiencies, and a high incidence of…”
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