Search Results - "GAITSKHOKI, V. S"

Two Novel Low-Density Lipoprotein Receptor Gene Mutations (E397X and 347delGCC) in St. Petersburg Familial Hypercholesterolemia by Kh, Chakir, Ju, Mandelshtam M., Shevtsov, S.P., Golubkov, V.I., Skobeleva, N.A., Shur, Yu.A., Zakharova, F.M., Lipovetskyi, B.M., Konstantinov, V.O., Denisenko, A.D., Gaitskhoki, V.S., Schwartz, E.I.

“…Familial hypercholesterolemia (FH), a monogenic disease known to be caused by low-density lipoprotein receptor (LDLR) gene mutations, results in the…”
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Study of intracellular localization and traffic of newly synthesized ceruloplasmin receptor in cultured human fibroblasts by Sasina, L K, Puchkova, L V, Gaitskhoki, V S

“…Ceruloplasmin (Cp) receptor in cells of non-hepatocyte lineage (human HT-1080 fibroblasts) is synthesized by membrane-bound polyribosomes and then becomes a…”
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Persistence of human mitochondrial DNA throughout the development to the blastocyst of mouse zygotes microinjected with human mitochondria by Vasilyev, V B, Sokolova, V A, Sorokin, A V, Bass, M G, Arbuzova, N I, Patkin, E L, Golubkov, V I, Dyban, A P, Gaitskhoki, V S

“…The conditions for transfer of human mitochondria into fertilised mouse ova were elaborated. Species-specific primers were designed to discriminate human…”
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Comparative analysis of the molecular heterogeneity of ceruloplasmin from human blood and breast milk by Puchkova, L V, Zakharova, E T, Aleinikova, T D, Mokshina, S V, Tsymbalenko, N V, Sasina, L K, Shirmanova, M R, Rogacheva, N P, Gaitskhoki, V S

“…The content of ceruloplasmin (Cp) was determined in 96 samples of human breast milk using rocket immunoelectrophoresis and measurement of Cp oxidase activity…”
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Isolation and partial characterization of molecular forms of ceruloplasmin from human bile by Verbina, Irene A., Puchkova, Ludmila V., Gaitskhoki, Vladimir S., Neifakh, Solomon A.

“…Highly purified ceruloplasmin (CP) was isolated from human bile using affinity chromatography. Billiary CP is represented by two molecular species. One of…”
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De novo mutation within the intron-exon junction in the PiZ allele of the alpha-1-antitrypsin gene by SCHWARZMAN, A. L, KOWALSKA, A, RUJNER, J, VLASOV, M. S, GAITSKHOKI, V. S

“…A proband homozygous for the PiZ allele of the alpha-1-antitrypsin gene was found to be a heterozygous carrier of the additional nucleotide substitution (C-T)…”
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Reconstitution of the intercellular transfer pathway of the peptide moiety of ceruloplasmin in mammals by Puchkova, L V, Sasina, L K, Aleinikova, T D, Zakharova, E T, Gaitskhoki, V S

“…According to rocket immunoelectrophoresis, the antigenic properties of the ceruloplasmin (Cp) receptor present on the surface of human fibroblasts are similar…”
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Isolation and partial characterization of cDNA clone of human ceruloplasmin receptor by Sasina, L K, Tsymbalenko, N V, Platonova, N A, Puchkova, L V, Voronina, O V, Gyulikhandanova, N E, Gaitskhoki, V S

“…An individual clone, presumably carrying a 3 bp fragment of ceruloplasmin receptor cDNA was isolated from the expression library of human placenta cDNA using…”
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Expression of cDNA fragment encoding ligand-binding domain of human low density lipoprotein receptor in Escherichia coli cells by Runova, O L, Mandelshtam MJu, Golubkov, V I, Sukonina, V E, Denisenko, A D, Gaitskhoki, V S

“…To study structure-function relationships in low density lipoprotein receptor (LDLR), a key protein in human cholesterol metabolism, it is reasonable to…”
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Correlation between molecular heterogeneity of ceruloplasmin mRNA and ceruloplasmin isomers synthesized in rat liver by Tsymbalenko, N. V., Aleinikova, T. D., Puchkova, L. V., Gaitskhoki, V. S.

“…Molecular heterogeneity of ceruloplasmin mRNA is studied in rat liver polyribosomes. Blot hybridization of RNA with cDNA reveals three molecular forms of…”
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Production and characterization of a recombinant ligand-binding domain of the human low-density lipoprotein receptor by Golubkov, V. I., Mandel’shtam, M. Yu, Runova, O. L., Gaitskhoki, V. S.

“…Two plasmids carrying the cDNA fragment of human low-density lipoprotein receptor coding for its ligand-binding domain are constructed. The ligand-binding…”
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Interaction of Lactoferrin with Ceruloplasmin by Zakharova, Elena T., Shavlovski, Mikhail M., Bass, Mikhail G., Gridasova, Anastasia A., Pulina, Maria O., De Filippis, Vincenzo, Beltramini, Mariano, Di Muro, Paolo, Salvato, Benedetto, Fontana, Angelo, Vasilyev, Vadim B., Gaitskhoki, Vladimir S.

“…When added to human blood serum, the iron-binding protein lactoferrin (LF) purified from breast milk interacts with ceruloplasmin (CP), a copper-containing…”
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Preproceruloplasmin is a primary product of cell-free translation of ceruloplasmin messenger RNA by Puchkova, L V, Gaitskhoki, V S, Monakhov, N K, Timchenko, L T, Neifakh, S A

“…Biosynthesis of ceruloplasmin was studied in wheat germ extract programmed with polysomal RNA from rat liver. Optimal potassium concentration for the total…”
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Identification of the linkage of mutations causing cystic fibrosis to different alleles of a tetranucleotide repeat in intron 6a of the CFTR gene by Potapova OYu, Voronina, O V, Gaitskhoki, V S, Bogacheva, E V, Uembitskaya, T E, Kuprina, E A, Kapranov, N I, Berlin YuA, Schwartz, E I

“…The linkage of the intragenic polymorphic (GATT)n repeat to a number of cystic fibrosis transmembrane conductance regulator gene mutations (delta F-508, G542X,…”
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Molecular heterogeneity of human hereditary diseases and problems of their gene therapy by Gaitskhoki, V. S.

“…The paper represents a review of up-to-date considerations concerning the primary mechanisms responsible for the deficiency of protein gene products in human…”
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Isolation and partial characterization of poly (A)-containing 7.5S messenger RNA from rat liver mitochondria by Kisselev, O.I., Gaitskhoki, V.S., Neifakh, S.A.

“…Poly(A)-containing low molecular weight (7.5S) messenger RNA was isolated in a highly purified form from both polyribosomes and post-polysomal. supernatant of…”
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The identification of the ceruloplasmin region interacting with the copper transferring menkes ATPase by Tsymbalenko, N. V., Platonova, N. A., Puchkova, L. V., Mokshina, S. V., Sasina, L. K., Skvortsova, N. N., Mishchenko, B. S., Egorov, Ts. A., Gaitskhoki, V. S.

“…The interaction was studied of ceruloplasmin (Cp, EC 1.16.3.1), a copper-containing plasma protein, with two synthetic peptides P15 and P16 whose structures…”
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Copper depletion/repletion of human ceruloplasmin is followed by the changes in its spectral features and functional properties by Vassiliev, Vadim B., Kachurin, Anatoly M., Beltramini, Mariano, Rocco, Gian Paolo, Salvato, Benedetto, Gaitskhoki, Vladimir S.

“…Copper ions of different types were gradually eliminated from ceruloplasmin (CP 1; ferro-O 2-oxidoreductase, EC 1.16.3.1.) by dialyzing the enzyme against KCN…”
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On the cell-free system of protein synthesis from mammalian mitochondria by Kisselev, O I, Gaitskhoki, V S, Neifakh, S A

“…Some properties of a submitochondrial cell-free system for protein synthesis are described. The system was prepared from rat liver mitochondria lysed with…”
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Polyribosomes and messenger RNA from rat liver mitochondria by Gaitskhoki, V S, Kisselev, O I, Klimov, N A

“…Rat liver mitochondrial polyribosomes were isolated free from cytoplasmic ribonucleoprotein contaminations in a number of criteria (sedimentation and buoyant…”
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