Search Results - "GAHLER, Roland J"

A Comparison and Safety Evaluation of Micellar versus Standard Vitamin D3 Oral Supplementation in a Randomized, Double-Blind Human Pilot Study by Solnier, Julia, Chang, Chuck, Zhang, Yiming, Kuo, Yun Chai, Du, Min, Roh, Yoon Seok, See, Janet, Brix, Jennifer, Gahler, Roland J., Green, Tim, Wood, Simon

“…The aim of this pilot study was to evaluate and compare bioavailability and safety of two Vitamin D3 formulations (softgels) in healthy adults, at single daily…”
Get full text

Effect of Fibre Supplementation on Body Weight and  Composition, Frequency of Eating and Dietary  Choice in Overweight Individuals by Solah, Vicky A, Kerr, Deborah A, Hunt, Wendy J, Johnson, Stuart K, Boushey, Carol J, Delp, Edward J, Meng, Xingqiong, Gahler, Roland J, James, Anthony P, Mukhtar, Aqif S, Fenton, Haelee K, Wood, Simon

“…Fibre supplementation can potentially reduce energy intake and contribute to weight loss. The mechanism may be reduced frequency of eating, resulting in…”
Get full text

Micronutrient status of individuals with overweight and obesity following 3 months' supplementation with PolyGlycopleX (PGX®) or psyllium: a randomized controlled trial by Pal, Sebely, McKay, Jenny, Ho, Suleen, Jane, Monica, Gahler, Roland J, Wood, Simon

“…Safe and effective weight control strategies are needed to curtail the current obesity epidemic worldwide. Increasing dietary fibre has shown positive results…”
Get full text

Effect of training on the reliability of satiety evaluation and use of trained panellists to determine the satiety effect of dietary fibre: a randomised controlled trial by Solah, Vicky A, Meng, Xingqiong, Wood, Simon, Gahler, Roland J, Kerr, Deborah A, James, Anthony P, Pal, Sebely, Fenton, Haelee K, Johnson, Stuart K

“…The assessment of satiety effects on foods is commonly performed by untrained volunteers marking their perceived hunger or fullness on line scales, marked with…”
Get full text

Effect of PolyGlycopleX (PGX) Consumption on Blood Lipid Profiles in Healthy, Low CVD Risk Overweight Adults by Solah, Vicky A, Kerr, Deborah A, Irawati, Deasy, Hunt, Wendy, Meng, Xingqiong, Gahler, Roland J, Fenton, Haelee K, Johnson, Stuart K, James, Anthony P, Wood, Simon

“…Raised blood lipid levels are associated with a risk of a cardiovascular disease (CVD). Moderate reductions in several CVD factors such as total, low-density…”
Get full text

Effect of the novel polysaccharide PolyGlycopleX® on short-chain fatty acid production in a computer-controlled in vitro model of the human large intestine by Reimer, Raylene A, Maathuis, Annet J H, Venema, Koen, Lyon, Michael R, Gahler, Roland J, Wood, Simon

“…Many of the health benefits associated with dietary fiber are attributed to their fermentation by microbiota and production of short chain fatty acids (SCFA)…”
Get full text

Consumption of the Soluble Dietary Fibre Complex PolyGlycopleX(®) Reduces Glycaemia and Increases Satiety of a Standard Meal Postprandially by Solah, Vicky A, O'Mara-Wallace, Babette, Meng, Xingqiong, Gahler, Roland J, Kerr, Deborah A, James, Anthony P, Fenton, Haelee K, Johnson, Stuart K, Wood, Simon

“…The effect of consumption of PolyGlycopleX(®) (PGX(®)) was compared to wheat dextrin (WD) in combination with a standard meal, on postprandial satiety and…”
Get full text

Effects of the soluble fiber complex PolyGlycopleX® (PGX®) on glycemic control, insulin secretion, and GLP-1 levels in Zucker diabetic rats by Grover, Gary J., Koetzner, Lee, Wicks, Joan, Gahler, Roland J., Lyon, Michael R., Reimer, Raylene A., Wood, Simon

“…The effects of the novel water soluble, viscous fiber complex PolyGlycopleX® [(α- d-glucurono-α- d-manno-β- d-manno-β- d-gluco), (α- l-gulurono-β- d…”
Get full text

Effects of the Soluble Fiber Complex PolyGlycopleX on Glucose Homeostasis and Body Weight in Young Zucker Diabetic Rats by Grover, Gary James, Koetzner, Lee, Wicks, Joan, Gahler, Roland J, Lyon, Michael R, Reimer, Raylene A, Wood, Simon

“…Dietary fiber can reduce insulin resistance, body weight, and hyperlipidemia depending on fiber type, water solubility, and viscosity. PolyGlycopleX(®)…”
Get full text

Effect of a functional fibre supplement on glycemic control when added to a year-long medically supervised weight management program in adults with type 2 diabetes by Reimer, Raylene A., Wharton, Sean, Green, Tim J., Manjoo, Priya, Ramay, Hena R., Lyon, Michael R., Gahler, Roland J., Wood, Simon

“…Purpose Soluble fibre beneficially affects metabolism but whether it can augment the reductions in glycemia induced through intensive weight management has not…”
Get full text

A Pharmacokinetic Study of Different Quercetin Formulations in Healthy Participants: A Diet-Controlled, Crossover, Single- and Multiple-Dose Pilot Study by Solnier, Julia, Zhang, Yiming, Roh, Kyle, Kuo, Yun Chai, Du, Min, Wood, Simon, Hardy, Mary, Gahler, Roland J., Chang, Chuck

“…This study aimed to evaluate the blood concentrations of quercetin in healthy participants after the administration of different formulations in single- and…”
Get full text

Effect on Insulin, Glucose and Lipids in Overweight/Obese Australian Adults of 12 Months Consumption of Two Different Fibre Supplements in a Randomised Trial by Pal, Sebely, Ho, Suleen, Gahler, Roland J, Wood, Simon

“…Higher fibre intakes are associated with risk reduction for chronic diseases. This study investigated the effects of supplementation with PolyGlycopleX (PGX),…”
Get full text

Effect on body weight and composition in overweight/obese Australian adults over 12 months consumption of two different types of fibre supplementation in a randomized trial by Pal, Sebely, Ho, Suleen, Gahler, Roland J, Wood, Simon

“…Higher fibre intakes are associated with risk reduction for chronic diseases. However, many people find difficulty in consuming sufficient fibre through their…”
Get full text

Combining sitagliptin/metformin with a functional fiber delays diabetes progression in Zucker rats by Reimer, Raylene A, Grover, Gary J, Koetzner, Lee, Gahler, Roland J, Lyon, Michael R, Wood, Simon

“…Our primary objective was to determine whether administering the viscous and fermentable polysaccharide PolyGlycopleX (PGX) with metformin (MET) or…”
Get full text

A randomized, double-blind, placebo-controlled, cross-over trial to evaluate the effect of EstroSense ® on 2-hydroxyestrone:16α-hydroxyestrone ratio in premenopausal women by Green, Tim, See, Janet, Schauch, Marita, Reil, Julie, Glover, Melissa, Brix, Jennifer, Gerry, Adella, Li, Kathy, Newman, Mark, Gahler, Roland J, Wood, Simon

“…Some estrogen metabolites are associated with increased breast cancer risk, while others are protective. Research efforts have focused on modifiable factors,…”
Get more information

Studies on macromolecular interactions in ternary mixtures of konjac glucomannan, xanthan gum and sodium alginate by Harding, Stephen E., Smith, Ian H., Lawson, Christopher J., Gahler, Roland J., Wood, Simon

“…Covalent and non-covalent macromolecular interactions were studied in the proprietary commercial product, PGX ® (PolyGlycopleX ®) which is manufactured from…”
Get full text

Changes in Visceral Adiposity and Serum Cholesterol with a Novel Viscous Polysaccharide in Japanese Adults with Abdominal Obesity by Reimer, Raylene A., Yamaguchi, Hideyo, Eller, Lindsay K., Lyon, Michael R., Gahler, Roland J., Kacinik, Veronica, Juneja, Prateek, Wood, Simon

“…Objective: Evidence supports the role of dietary fiber in improving metabolic health. PolyGlycopleX® (PGX®), a viscous functional polysaccharide improves…”
Get full text

Effect of two different fibre supplements on blood pressure, arterial stiffness and C-reactive protein in adults with overweight and obesity consumed over 12 months, in a randomised controlled trial by Pal, Sebely, Jane, Monica, Ho, Suleen, Gahler, Roland J., Wood, Simon

“…Adequate fibre consumption is associated with reduced risk of metabolic syndrome and cardiovascular disease. This study examined the effects of supplementation…”
Get full text

Dose–response effect of a novel functional fibre, PolyGlycopleX®, PGX®, on satiety by Solah, Vicky A., Brand-Miller, Jennie C., Atkinson, Fiona S., Gahler, Roland J., Kacinik, Veronica, Lyon, Michael R., Wood, Simon

“…•A satiety dose–response effect of 2.5 and 7.5 g PGX® consumed at breakfast was found.•A 34% increase in fullness compared with the inulin control was provided…”
Get full text

Designing Vitamin D3 Formulations: An In Vitro Investigation Using a Novel Micellar Delivery System by Du, Min, Chang, Chuck, Zhang, Xin, Zhang, Yiming, Radford, Melissa J., Gahler, Roland J., Kuo, Yun Chai, Wood, Simon, Solnier, Julia

“…Vitamin D is an essential nutrient with important immunomodulatory properties. As a fat-soluble compound, Vitamin D (and its D3 form) is immiscible with water,…”
Get full text