Search Results - "GACAR, NEJAT"

Resveratrol exerts anti-inflammatory and neuroprotective effects to prevent memory deficits in rats exposed to chronic unpredictable mild stress by Yazir, Yusufhan, Utkan, Tijen, Gacar, Nejat, Aricioglu, Feyza

“…Abstract A number of studies have recently focused on the neuroprotective and anti-inflammatory effects of resveratrol. In prior studies, we described its…”
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Protective effects of resveratrol on aging-induced cognitive impairment in rats by Gocmez, Semil Selcen, Gacar, Nejat, Utkan, Tijen, Gacar, Gulcin, Scarpace, Philip J., Tumer, Nihal

“…•Aging impaired emotional and spatial learning and memory in rats.•Inflammatory cytokines were increased by aging.•Resveratrol reversed the aging impaired…”
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Effects of Resveratrol on Ileal Smooth Muscle Reactivity in Polymicrobial Sepsis Model by Gacar, Nejat, Ph.D, Gocmez, Selcen, Ph.D, Utkan, Tijen, Ph.D, Gacar, Gulcin, Ph.D, Komsuoglu, Ipek, M.D., Ph.D, Tugay, Melih, M.D, Utkan, N. Zafer, M.D

“…Objective To determine the effects of resveratrol on the ileal smooth muscle reactivity in polymicrobial sepsis. Material and Methods Polimicrobial sepsis was…”
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Blood pressure and vascular reactivity to endothelin-1, phenylephrine, serotonin, KCl and acetylcholine following chronic alcohol consumption in vitro by Utkan, Tijen, Yildiz, Firuzan, Ilbay, Gül, Özdemirci, Sitki, Erden, Bekir Faruk, Gacar, Nejat, Ulak, Güner

“…Ethanol has been reported to cause hypertension, the mechanism of which is unknown. Therefore, the effect of chronic ethanol consumption on vascular…”
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Chronic administration of imipramine but not agomelatine and moclobemide affects the nitrergic relaxation of rabbit corpus cavernosum smooth muscle by Gocmez, Semil Selcen, Utkan, Tijen, Gacar, Nejat

“…Sexual dysfunction is a common and underestimated effect of antidepressants. However, the mechanism by which these drugs cause erectile dysfunction is unclear…”
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Beneficial effects of resveratrol on scopolamine but not mecamylamine induced memory impairment in the passive avoidance and Morris water maze tests in rats by Gacar, Nejat, Mutlu, Oguz, Utkan, Tijen, Komsuoglu Celikyurt, Ipek, Gocmez, Semil Selcen, Ulak, Güner

“…Resveratrol (3,5,4-trihydroxy-trans-stilbene), which is found in grapes and red wine has been shown to protect neuronal cells with its antioxidant activity,…”
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The therapeutic effects of resveratrol on MSCs cell-based strategies on degenerative bone disease by Gacar, Gülçin, Yusufoğlu, Sema, Gacar, Nejat, Ünal, Zehra Seda, Utkan, Tijen

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The Link Between Unpredictable Chronic Mild Stress Model for Depression and Vascular Inflammation? by Demirtaş, Tuğçe, Utkan, Tijen, Karson, Ayşe, Yazır, Yusufhan, Bayramgürler, Dilek, Gacar, Nejat

“…Inflammation has been suggested to be associated with stress-induced depression and cardiovascular dysfunction. Tumor necrosis factor alpha (TNF-α) is a major…”
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Effects of YC-1 on learning and memory functions of aged rats by Komsuoglu Celikyurt, Ipek, Utkan, Tijen, Ozer, Cuneyt, Gacar, Nejat, Aricioglu, Feyza

“…The aim of this study was to investigate the effects of a potent nitric oxide-guanylate cyclase activator, 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole…”
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Selective and nonselective neuronal NOS inhibitors impair cognitive function in the three panel runway and passive avoidance tasks in rats by Utkan, Tijen, Gocmez, Semil Selcen, Ozer, Cuneyt, Gacar, Nejat, Aricioglu, Feyza

“…The aim of this study was to compare the effects of both neuronal NOS (nNOS) and inducible NOS (iNOS) inhibitor 2-iminobiotin, with the more selective nNOS…”
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Evidence for the involvement of neuronal nitric oxide synthase and soluble guanylate cyclase on cognitive functions in rats by Komsuoglu-Celikyurt, Ipek, Gocmez, Semil S., Mutlu, Oguz, Gacar, Nejat, Aricioglu, Feyza, Utkan, Tijen

“…The influence of 3-bromo-7-nitroindazole (3-Br 7-NI), a potent and selective neuronal nitric oxide synthase (nNOS) inhibitor, and…”
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Chronic administration of fluoxetine impairs neurogenic and endothelium-dependent relaxation of the rabbit corpus cavernosum smooth muscle by Göçmez, Semil Selcen, Utkan, Tijen, Gacar, Nejat, Sarioglu, Yusuf

“…Antidepressants, including selective serotonin reuptake inhibitors (SSRIs), cause erectile dysfunction; however, the mechanism by which they cause erectile…”
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Investigation on the mechanism involved in the effects of agmatine on ethanol-induced gastric mucosal injury in rats by Utkan, Tijen, Ulak, Güner, Gökalp Yildiran, H, Yardemoglu, Melda, Nejat Gacar, M

“…Effects of agmatine, an endogenous metabolite formed by decarboxylation of L-arginine, on ethanol-induced gastric mucosal injury were investigated in rats…”
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7-Nitroindazole, a neuronal nitric oxide synthase inhibitor, impairs passive-avoidance and elevated plus-maze memory performance in rats by Yildiz Akar, Furuzan, Ulak, Guner, Tanyeri, Pelin, Erden, Faruk, Utkan, Tijen, Gacar, Nejat

“…The role of nitric oxide (NO) on cognitive performance in a modified elevated plus-maze (mEPM) and passive-avoidance (PA) task was investigated by using the NO…”
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Antidepressant-like effect of 7-nitroindazole in the forced swimming test in rats by YILDIZ, F, ERDEN, B. F, ULAK, G, UTKAN, T, GACAR, N

“…There is some strong evidence about the role of nitric oxide (NO) as an intercellular messenger in central physiological mechanisms. NO is synthesized from…”
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The effect of hydrocephalus on lower esophageal sphincter smooth muscle reactivity: experimental study by Etus, Volkan, Tugay, Melih, Utkan, Tijen, Ceylan, Savas, Gacar, Nejat

“…Abstract Purpose The aim of this study was to assess the pharmacophysiological significance of the enteric nervous system for the mechanical responses of lower…”
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Age-related smooth muscle reactivity changes in the rat bladder: an in vitro study by Tugay, Melih, Yildiz, Fürüzan, Utkan, Tijen, Gacar, Nejat, Ulak, Güner, Erden, Faruk

“…An experimental study was conducted to investigate developmental changes of the rat detrusor smooth muscle (DSM) reactivity from newborn to adult period…”
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Gastric smooth muscle contractility changes in the esophageal atresia rat model: an in vitro study by Tugay, Melih, Yildiz, Fürüzan, Utkan, Tijen, Sarıoglu, Yusuf, Gacar, Nejat

“…Purpose: The aim of the study was to investigate the gastric smooth muscle reactivity in the Adriamycin-induced esophageal atresia (EA) rat model. Methods: The…”
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Kalp-damar hastalıkları farmakolojisi: Editörler M. Nejat Gacar, Baki Komsuoğlu, Tijen Utkan by Gacar, Mehmet Nejat, Komsuoğlu, Baki, Utkan, Tijen

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Esophagitis impairs esophageal smooth muscle reactivity in the rat model: An in vitro study by TUGAY, Melih, YILDIZ, Firuzan, UTKAN, Tijen, MÜEZZINOGLU, Bahar, ERDEN, Faruk, GACAR, Nejat, ULAK, Güner

“…The present study investigated how reflux-induced esophagitis affects the smooth muscle reactivity of the esophageal body. Two different esophagitis models…”
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