Search Results - "GABRIEL, Iwona"
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'Acridines' as New Horizons in Antifungal Treatment
Published in Molecules (Basel, Switzerland) (25-03-2020)“…Frequent fungal infections in immunocompromised patients and mortality due to invasive mycosis are important clinical problems. Opportunistic pathogenic…”
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2
Targeting DNA Topoisomerase II in Antifungal Chemotherapy
Published in Molecules (Basel, Switzerland) (11-11-2022)“…Topoisomerase inhibitors have been in use clinically for the treatment of several diseases for decades. Although those enzymes are significant molecular…”
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3
The Current Evidence on the Association Between the Urinary Microbiome and Urinary Incontinence in Women
Published in Frontiers in cellular and infection microbiology (01-05-2019)“…Urinary incontinence (UI) is a burdensome condition with high prevalence in middle-aged to older women and an unclear etiology. Advances in our understanding…”
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4
Inhibitors of amino acids biosynthesis as antifungal agents
Published in Amino acids (01-02-2015)“…Fungal microorganisms, including the human pathogenic yeast and filamentous fungi, are able to synthesize all proteinogenic amino acids, including nine that…”
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5
Fungal L-Methionine Biosynthesis Pathway Enzymes and Their Applications in Various Scientific and Commercial Fields
Published in Biomolecules (Basel, Switzerland) (17-10-2024)“…L-methionine (L-Met) is one of the nine proteinogenic amino acids essential for humans since, in human cells, there are no complete pathways for its…”
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Targeting Candida albicans O-acetyl-L-homoserine sulfhydrylase (Met15p) in antifungal treatment
Published in Scientific reports (15-11-2024)“…Fungal infections are a serious threat to public health as they are becoming increasingly frequent. A major problem stems also from a rising fungal resistance…”
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Xanthone synthetic derivatives with high anticandidal activity and positive mycostatic selectivity index values
Published in Scientific reports (23-07-2023)“…With the current massive increases in drug-resistant microbial infection as well as the significant role of fungal infections in the death toll of COVID-19,…”
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Antifungal Effect of Penicillamine Due to the Selective Targeting of L-Homoserine O-Acetyltransferase
Published in International journal of molecular sciences (14-07-2022)“…Due to the apparent similarity of fungal and mammalian metabolic pathways, the number of established antifungal targets is low, and the identification of novel…”
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A Novel Method of Endotoxins Removal from Chitosan Hydrogel as a Potential Bioink Component Obtained by CO2 Saturation
Published in International journal of molecular sciences (14-05-2022)“…The article presents a new approach in the purification of chitosan (CS) hydrogel in order to remove a significant amount of endotoxins without changing its…”
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10
Targeting yeast topoisomerase II by imidazo and triazoloacridinone derivatives resulting in their antifungal activity
Published in Scientific reports (13-02-2024)“…Fungal pathogens are considered as serious factors for deadly diseases and are a case of medical concern. Invasive fungal infections also complicate the…”
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11
Douching, Talc Use, and Risk for Ovarian Cancer and Conditions Related to Genital Tract Inflammation
Published in Cancer epidemiology, biomarkers & prevention (01-11-2019)“…Douching is associated with disorders involving genital tract inflammation and genital talc use with epithelial ovarian cancer (EOC), but their joint effects…”
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12
The Effect of Conjugation with Octaarginine, a Cell-Penetrating Peptide on Antifungal Activity of Imidazoacridinone Derivative
Published in International journal of molecular sciences (07-12-2021)“…Acridine cell-penetrating peptide conjugates are an extremely important family of compounds in antitumor chemotherapy. These conjugates are not so widely…”
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Quest for the Molecular Basis of Improved Selective Toxicity of All-Trans Isomers of Aromatic Heptaene Macrolide Antifungal Antibiotics
Published in International journal of molecular sciences (18-09-2021)“…Three aromatic heptaene macrolide antifungal antibiotics, Candicidin D, Partricin A (Gedamycin) and Partricin B (Vacidin) were subjected to controlled…”
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14
Analysis of microRNA regulating cell cycle-related tumor suppressor genes in endometrial cancer patients
Published in Human cell : official journal of Human Cell Research Society (01-03-2021)“…Endometrial cancer remains the most common malignancy of the female genital system in developed countries. Tumor suppressor genes are responsible for…”
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Enzymes of UDP‐GlcNAc biosynthesis in yeast
Published in Yeast (Chichester, England) (15-01-2006)“…D‐Glucosamine is an important building block of major structural components of the fungal cell wall, namely chitin, chitosan and mannoproteins. Other amino…”
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Intravesical Extrusion of a Single-Incision Midurethral Sling Anchor With a Simple Transurethral Resection Technique: A Case Report
Published in Female pelvic medicine & reconstructive surgery (01-11-2019)“…ABSTRACTSingle-incision midurethral slings were introduced in 2006 with the goal of providing shorter operative time, less postoperative pain, and decreased…”
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Antifungal Activity of Capridine β as a Consequence of Its Biotransformation into Metabolite Affecting Yeast Topoisomerase II Activity
Published in Pathogens (Basel) (09-02-2021)“…In the last few years, increasing importance is attached to problems caused by fungal pathogens. Current methods of preventing fungal infections remain…”
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18
Antifungal activity of homoaconitate and homoisocitrate analogs
Published in Molecules (Basel, Switzerland) (27-11-2012)“…Thirteen structural analogs of two initial intermediates of the L-α-aminoadipate pathway of L-lysine biosynthesis in fungi have been designed and synthesized,…”
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Enhanced Susceptibility to Antifungal Oligopeptides in Yeast Strains Overexpressing ABC Multidrug Efflux Pumps
Published in Antimicrobial Agents and Chemotherapy (01-11-2008)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Cornual ectopic pregnancy -Case report
Published in European journal of obstetrics & gynecology and reproductive biology (01-02-2024)Get full text
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