Search Results - "G.K, Rajanikant"
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Role of Autophagy in Endothelial Damage and Blood–Brain Barrier Disruption in Ischemic Stroke
Published in Stroke (1970) (01-06-2018)Get full text
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Calcium ion--the key player in cerebral ischemia
Published in Current medicinal chemistry (2014)“…Role of calcium ion (Ca2+) in the functioning of neurons from their naïve state to mature state is of vital importance. It controls functions such as neuronal…”
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Nanotechnology and nanomedicine: going small means aiming big
Published in Current pharmaceutical design (01-06-2010)“…Nanotechnology is an emerging branch of science for designing tools and devices of size 1 to 100 nm with specific function at the cellular, atomic and…”
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Experimental investigation into the effects of electric discharge surface modification process parameters on the biocompatibility of Ti6Al4V
Published in Biomedical engineering advances (01-12-2022)“…Titanium alloys especially Ti6Al4V is extensively used in the fabrication of biomedical implant due to its similar mechanical properties as of bone, bio…”
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Carnosine is neuroprotective against permanent focal cerebral ischemia in mice
Published in Stroke (1970) (01-11-2007)“…Carnosine is a naturally occurring dipeptide with multiple neuroprotective properties. In addition, it is well tolerated in high doses with minimal side…”
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Carnosine Protects against Cerebral Ischemic Injury by Inhibiting Matrix-Metalloproteinases
Published in International journal of molecular sciences (13-07-2021)“…Stroke is one of the leading causes of death and disability worldwide. However, treatment options for ischemic stroke remain limited. Matrix-metalloproteinases…”
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Alpha-linolenic acid suppresses dopaminergic neurodegeneration induced by 6-OHDA in C. elegans
Published in Physiology & behavior (01-11-2015)“…Abstract Parkinson's disease (PD) is the second most common neurodegenerative disorder characterized by the specific and massive loss of dopamine (DA)…”
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Necroptosis: who knew there were so many interesting ways to die?
Published in CNS & neurological disorders drug targets (01-02-2014)“…Conventional knowledge considered apoptosis as the sole form of programmed cell death during development, homeostasis and diseases, whereas necrosis was…”
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Drp1 in ischemic neuronal death: an unusual suspect
Published in Current medicinal chemistry (2014)“…Mitochondria play a crucial role in multitude of cellular processes including energy production, calcium signaling, and apoptosis. This remarkable organelle…”
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Computational identification of novel histone deacetylase inhibitors by docking based QSAR
Published in Computers in biology and medicine (01-06-2012)“…Abstract Histone deacetylases (HDACs) are enzymes that modify chromatin structure and contribute to aberrant gene expression in cancer. A series compounds with…”
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Nanotechnology based diagnostic and therapeutic strategies for neuroscience with special emphasis on ischemic stroke
Published in Current medicinal chemistry (01-02-2012)“…Ischemic stroke is the second leading cause of death and long-term disability worldwide, for which no effective therapies are available. The increasing…”
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Post stroke depression: The sequelae of cerebral stroke
Published in Neuroscience and biobehavioral reviews (01-07-2018)“…•Post-stroke depression is a frequent neuropsychiatric manifestation of high clinical importance.•The pathophysiology of post-stroke depression is poorly…”
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Ascorbic acid increases healing of excision wounds of mice whole body exposed to different doses of γ-radiation
Published in Burns (01-06-2007)“…Abstract Because of the practical importance of acute radiation exposure associated with combined injuries, it is imperative to investigate the efficacy of…”
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Effect of curcumin on radiation-impaired healing of excisional wounds in mice
Published in Journal of wound care (01-03-2004)“…Objective: To study the effect on wound contraction of pretreatment with various doses of curcumin (the most important active ingredient of the spice turmeric)…”
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Effect of abana (a herbal preparation) on the radiation-induced mortality in mice
Published in Journal of ethnopharmacology (01-06-2003)“…The effect of various doses (0, 5, 10, 20, 40 and 80 mg/kg body weight) of 50% ethanolic extract of abana, a traditional herbal preparation, widely used in…”
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Electrophoretic deposition of alginate/bioglass composite coating on MgCa alloy for degradable metallic implant applications
Published in Surface & coatings technology (25-10-2022)“…Surface modifications using bioactive coatings can be utilized effectively to tailor the rate of degradation and enhance biomineralization of magnesium (Mg)…”
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Electrophoretic deposition of alginate/bioglass composite coating on Mg Ca alloy for degradable metallic implant applications
Published in Surface & coatings technology (25-10-2022)Get full text
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High doses of clethodim-based herbicide GrassOut Max poses reproductive hazard by affecting male reproductive function and early embryogenesis in Swiss albino mice
Published in Chemosphere (Oxford) (01-09-2023)“…Clethodim is a widely used and approved class II herbicide, with little information about its impact on the reproductive system. Herein, we investigated the…”
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