Search Results - "G. Henshall, Isabelle"

Defining species-specific and conserved interactions of apical membrane protein 1 during erythrocyte invasion in malaria to inform multi-species vaccines by Drew, Damien R., Wilson, Danny W., Weiss, Gretchen E., Yeoh, Lee M., G. Henshall, Isabelle, Crabb, Brendan S., Dutta, Sheetij, Gilson, Paul R., Beeson, James G.

“…Plasmodium falciparum and P. vivax are the major causes of human malaria, and P. knowlesi is an important additional cause in SE Asia. Binding of apical…”
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The Kelch13 compartment contains highly divergent vesicle trafficking proteins in malaria parasites by Schmidt, Sabine, Wichers-Misterek, Jan Stephan, Behrens, Hannah Michaela, Birnbaum, Jakob, Henshall, Isabelle G, Dröge, Jana, Jonscher, Ernst, Flemming, Sven, Castro-Peña, Carolina, Mesén-Ramírez, Paolo, Spielmann, Tobias

“…Single amino acid changes in the parasite protein Kelch13 (K13) result in reduced susceptibility of P. falciparum parasites to artemisinin and its derivatives…”
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Impact of different mutations on Kelch13 protein levels, ART resistance, and fitness cost in Plasmodium falciparum parasites by Behrens, Hannah M, Schmidt, Sabine, Henshall, Isabelle G, López-Barona, Patricia, Peigney, Domitille, Sabitzki, Ricarda, May, Jürgen, Maïga-Ascofaré, Oumou, Spielmann, Tobias

“…Reduced susceptibility to ART, the first-line treatment against malaria, is common in South East Asia (SEA). It is associated with point mutations, mostly in (…”
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Cellular dissection of malaria parasite invasion of human erythrocytes using viable Plasmodium knowlesi merozoites by Lyth, Oliver, Vizcay-Barrena, Gema, Wright, Katherine E., Haase, Silvia, Mohring, Franziska, Najer, Adrian, Henshall, Isabelle G., Ashdown, George W., Bannister, Lawrence H., Drew, Damien R., Beeson, James G., Fleck, Roland A., Moon, Robert W., Wilson, Danny W., Baum, Jake

“…Plasmodium knowlesi , a zoonotic parasite causing severe-to-lethal malaria disease in humans, has only recently been adapted to continuous culture with human…”
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Critical interdependencies between Plasmodium nutrient flux and drugs by Henshall, Isabelle G., Spielmann, Tobias

“…The unique nature of many Plasmodium falciparum nutrient acquisition pathways provides potential drug targets.P. falciparum-derived broad, nonspecific uptake…”
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