Search Results - "G. Fraga, Cesar"
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Plant bioactives and redox signaling: (–)-Epicatechin as a paradigm
Published in Molecular aspects of medicine (01-06-2018)“…Polyphenols are bioactives claimed to be responsible for some of the health benefits provided by fruit and vegetables. It is currently accepted that the…”
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Basic biochemical mechanisms behind the health benefits of polyphenols
Published in Molecular aspects of medicine (01-12-2010)“…Polyphenols and consequently many flavonoids have several beneficial actions on human health. However, the actual molecular interactions of polyphenols with…”
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3
In vitro measurements and interpretation of total antioxidant capacity
Published in Biochimica et biophysica acta (01-02-2014)“…One of the strategies most commonly used to assess a free radical-antioxidant balance in chemical and biological systems is the determination of the total…”
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4
(–)-Epicatechin in the control of glucose homeostasis: Involvement of redox-regulated mechanisms
Published in Free radical biology & medicine (01-01-2019)“…Emerging evidence supports a beneficial action of the flavan-3-ol (–)-epicatechin (EC) on insulin sensitivity and potential impact on the…”
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5
(-)-Epicatechin improves insulin sensitivity in high fat diet-fed mice
Published in Archives of biochemistry and biophysics (01-06-2016)“…Obesity constitutes a major public health concern, being frequently associated with type 2 diabetes (T2D). Evidence from studies in humans and experimental…”
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6
Hypertension, nitric oxide, oxidants, and dietary plant polyphenols
Published in Current pharmaceutical biotechnology (01-12-2010)“…Fruits and vegetables are key foods whose high ingestion is associated with the improvement of numerous pathological conditions, including hypertension. Such…”
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7
Anthocyanins protect the gastrointestinal tract from high fat diet-induced alterations in redox signaling, barrier integrity and dysbiosis
Published in Redox biology (01-09-2019)“…The gastrointestinal (GI) tract can play a critical role in the development of pathologies associated with overeating, overweight and obesity. We previously…”
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8
Linking biomarkers of oxidative stress and disease with flavonoid consumption: From experimental models to humans
Published in Redox biology (01-06-2021)“…Identification of the links among flavonoid consumption, mitigation of oxidative stress and improvement of disease in humans has significantly advanced in the…”
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Cyanidin and delphinidin modulate inflammation and altered redox signaling improving insulin resistance in high fat-fed mice
Published in Redox biology (01-09-2018)“…Consumption of diets high in fat and/or fructose content promotes tissue inflammation, oxidative stress, and insulin resistance, activating signals (e.g…”
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Antioxidant actions of flavonoids: Thermodynamic and kinetic analysis
Published in Archives of biochemistry and biophysics (01-09-2010)“…The benefits of flavonoids on human health are very often ascribed to their potential ability to act diminishing free radical steady state concentration in…”
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11
LPS-induced renal inflammation is prevented by (−)‐epicatechin in rats
Published in Redox biology (01-04-2017)“…This work investigated the capacity of (−)-epicatechin to prevent the renal damage induced by LPS administration in rats. Male Sprague Dawley rats were fed for…”
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12
Flavonoids and metabolic syndrome
Published in Annals of the New York Academy of Sciences (01-07-2012)“…Increasing evidence indicates that several mechanisms, associated or not with antioxidant actions, are involved in the effects of flavonoids on health…”
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13
(Poly)phenols and the regulation of NADPH oxidases
Published in Redox biology (01-11-2023)“…Nicotinamide adenine dinucleotide phosphate (NADPH) oxidases (NOXs) are enzymes that generate superoxide anion (O2•-) and hydrogen peroxide (H2O2), and that…”
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14
A randomized placebo-controlled cross-over study on the effects of anthocyanins on inflammatory and metabolic responses to a high-fat meal in healthy subjects
Published in Redox biology (01-05-2022)“…This study investigated the effects of supplementation with a cyanidin- and delphinidin-rich extract (CDRE) on the postprandial dysmetabolism, inflammation,…”
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15
Research trends in flavonoids and health
Published in Archives of biochemistry and biophysics (15-05-2018)“…Herein we describe, based on some bibliometric data, how the field of research on flavonoids has evolved over the last 25 years. The number of papers on…”
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Inhibition of Angiotensin Converting Enzyme Activity by Flavanol-Rich Foods
Published in Journal of agricultural and food chemistry (11-01-2006)“…Angiotensin converting enzyme (ACE) activity was evaluated in the presence of flavanol-rich foods, i.e., wines, chocolates, and teas, and of purified…”
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17
Cocoa flavanols: effects on vascular nitric oxide and blood pressure
Published in Journal of Clinical Biochemistry and Nutrition (01-01-2011)“…Diets rich in fruits and vegetables have been associated with benefits for human health. Those effects have been partially ascribed to their content in…”
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Cocoa antioxidants and cardiovascular health
Published in The American journal of clinical nutrition (2005)“…An increasing body of epidemiologic evidence supports the concept that diets rich in fruits and vegetables can promote health and attenuate, or delay, the…”
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Journal Article Conference Proceeding -
19
Procyanidin dimer B2 [epicatechin-(4β-8)-epicatechin] in human plasma after the consumption of a flavanol-rich cocoa
Published in The American journal of clinical nutrition (01-10-2002)“…Background: Epidemiologic studies have linked flavonoid-rich foods with a reduced risk of cardiovascular mortality. Some cocoas are flavonoid-rich and contain…”
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Inhibition of angiotensin converting enzyme (ACE) activity by flavan-3-ols and procyanidins
Published in FEBS letters (18-12-2003)“…It was determined that flavan-3-ols and procyanidins have an inhibitory effect on angiotensin I converting enzyme (ACE) activity, and the effect was dependent…”
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