Search Results - "G. E. Pozmogova"

Genetically encoded calcium indicator with NTnC-like design and enhanced fluorescence contrast and kinetics by Doronin, D A, Barykina, N V, Subach, O M, Sotskov, V P, Plusnin, V V, Ivleva, O A, Isaakova, E A, Varizhuk, A M, Pozmogova, G E, Malyshev, A Y, Smirnov, I V, Piatkevich, K D, Anokhin, K V, Enikolopov, G N, Subach, F V

“…The recently developed genetically encoded calcium indicator (GECI), called NTnC, has a novel design with reduced size due to utilization of the troponin C…”
Get full text

Byproduct with Altered Fluorescent Properties Is Formed during Standard Deprotection Step of Hexachlorofluorescein Labeled Oligonucleotides by Chuvilin, A. N, Serebryakova, M. V, Smirnov, I. P, Pozmogova, G. E

“…HEX-labeled oligonucleotides obtained via typical synthetic protocols may contain more than 15% of material with altered spectral characteristics. We…”
Get full text

Anticoagulant Effects of Thioanalogs of Thrombin-Binding DNA-Aptamer and Their Stability in the Plasma by Pozmogova, G. E, Zaitseva, M. A, Smirnov, I. P, Shvachko, A. G, Murina, M. A, Sergeenko, V. I

“…In order to create effective therapeutically signifi cant oligonucleotide structures, a series of analogs of thrombin-binding aptamer d(GGTTGGTGTGGTTGG)…”
Get full text

Conformational polymorphysm of G-rich fragments of DNA Alu-repeats. I. Noncanonical structures by Sekridova, A. V., Varizhuk, A. M., Tatarinova, O. N., Severov, V. V., Barinov, N. A., Smirnov, I. P., Lazarev, V. N., Klinov, D. V., Pozmogova, G. E.

“…We report results of the first systematic study of conformational polymorphism of G-rich DNA fragments of Alu-repeats. Alu retrotransposons are…”
Get full text

The Role of Mutant RNA in the Pathogenesis of Huntington’s Disease and Other Polyglutamine Diseases by Bogomazova, A. N., Eremeev, A. V., Pozmogova, G. E., Lagarkova, M. A.

“…— Polyglutamine diseases are rare, inherited neurodegenerative pathologies that arise as a result of expansion of trinucleotide CAG repeats in the coding…”
Get full text

Principles of creation of protein carriers of DNA new derivatives of human epidermal growth factor for gene therapy by Pozmogova, G E, Chuvilin, A N

“…We formulated a new approach to the creation of transport proteins for the delivery of foreign DNA to target cells and used it for obtaining a polypeptide…”
Get full text

Conformational polymorphysm of G-rich fragments of DNA Alu-repeats. II. The putative role of G-quadruplex structures in genomic rearrangements by Varizhuk, A. M., Sekridova, A. V., Tankevich, M. V., Podgorsky, V. S., Smirnov, I. P., Pozmogova, G. E.

“…Three evolutionary conserved (G-rich) sites of Alu repeats (PQS2, PQS3, and PQS4) could form in vitro stable inter- and intramolecular G-quadruplexes (GQs)…”
Get full text

Detection of DNA molecules in a lipid nanotube channel in the low ion strength conditions by Chekashkina, K. V., Galimzyanov, T. R., Kuzmin, P. I., Akimov, S. A., Romanov, S. A., Pozmogova, G. E., Klinov, D. V., Bashkirov, P. V.

“…Investigation of the transport phenomena in the nanoscopic channels/pores with the diameter smaller than 100 nm is of utmost importance for various biological,…”
Get full text

Complexes of telomeric oligonucleotides with the PGEk protein vector: Internalization by target cells and antiproliferative activity by Posypanova, G. A., Chuvilin, A. N., Kireeva, N. N., Severin, E. S., Pozmogova, G. E.

“…Recombinant protein PGEk, consisting of the human epidermal growth factor (hEGF) and a DNA-binding domain, proved to be capable of interacting with the hEGF…”
Get full text

Conformational polymorphysm of G-rich fragments of DNA Alu-repeats. II. the putative role of G-quadruplex structures in genomic rearrangements by Varizhuk, A M, Sekridova, A V, Tankevich, M V, Podgorsky, V S, Smirnov, I P, Pozmogova, G E

“…Three evolutionary conserved sites of Alu repeats (PQS2, PQS3 and PQS4) were shown to form stable inter- and intramolecular G-quadruplexes (GQs) in vitro…”
Get more information

Significance of methods for purification of oligodeoxyribonucleotide probes for the efficiency of gene diagnosis by real-time PCR by Tatarinova, O. N., Lukyanova, T. N., Zaitseva, M. A., Veremeev, K. Yu, Karpov, V. A., Chuvilin, A. N., Petrunin, D. D., Pozmogova, G. E.

“…Analysis of the use of real-time PCR with fluorescent registration of results for gene diagnosis of infectious diseases showed that the sensitivity and…”
Get full text

The synthesis and mass spectrometry of oligonucleotides bearing thiophosphoryl modifications of the predetermined localization by Luk'ianova, T A, Zaííítseva, M A, Karpov, V A, Pozmogova, G E

“…The technique of parallel automated synthesis of oligodeoxynucleotides bearing various local thiophosphoryl internucleotide bonds was optimized using…”
Get more information

Preparation and properties of associates of nickel nanoparticles with ss-DNA and proteins by Pozmogova, G. E., Chuvilin, A. N., Smirnov, I. P., Zaitseva, M. A., Tatarinova, O. N., Govorun, V. M.

“…In this paper, we demonstrate that nickel nanoparticles are suitable and promising for forming multifunctional biopolymer structures and have advantages over…”
Get full text

synthesis and mass spectrometry of oligonucleotides bearing thiophosphoryl modifications of the predetermined localization by Luk'yanova, T. A, Zaitseva, M. A, Karpov, V. A, Pozmogova, G. E

“…The technique of parallel automated synthesis of oligodeoxynucleotides bearing various local thiophosphoryl internucleotide bonds was optimized using…”
Get full text

Telomeric oligonucleotide complexes with PGEk protein vector: internalization by target cells and antiproliferative properties by Posypanova, G A, Chuvilin, A N, Kireeva, N N, Severin, E S, Pozmogova, G E

“…The recombinant protein PGEk, containing residual of the human epidermal factor (hEGF) bearing DNA binding sequence, retains ability of hEGF to bind with hEGF…”
Get more information

Complexes of telomeric oligonucleotide d(TTAGGG)4 with the new recombinant protein PGEk--nucleic acid carrier into proliferating cells by Besschetnova, I A, Pozmogova, G E, Chuvilin, A N, Shchelkina, A K, Borisova, O F

“…The complexation of the new protein vector PGEk--a carrier of nucleic acids into proliferating cells with phosphodiester d(TTAGGG)4 (TMO) and phosphorothioate…”
Get more information

Complexes of telomeric oligonucleotide d(TTAGGG)4 with the new recombinant protein vector PGEk carrying nucleic acids into proliferating cells by Besschetnova, I. A., Pozmogova, G. E., Chuvilin, A. N., Shchyolkina, A. K., Borisova, O. F.

“…A study was made of the complexation of the protein vector PGEk, which transfers nucleic acids into the nuclei of cancer cells, with phosphodiester…”
Get full text

The Role of Mutant RNA in the Pathogenesis of Huntington's Disease and Other Polyglutamine Diseases by Bogomazova, A N, Eremeev, A V, Pozmogova, G E, Lagarkova, M A

“…Polyglutamine diseases are rare, inherited neurodegenerative pathologies that arise as a result of expansion of trinucleotide CAG repeats in the coding segment…”
Get more information

Conformational Polymorphism and Extensibility of DNA Quadruplexes Formed by d(GT)nRepeats by Borisova, O F, Shchyolkina, A K, Il'icheva, I A, Pozmogova, G E

“…We showed earlier that oligonucleotides 3"-d(GT)^sub 5^-pO(CH^sub 2^CH^sub 2^O)^sub 3^p-d(GT)^sub 5^-3" form bimolecular quadruplexes with parallel orientation…”
Get full text

An approach to construction of hybrid polypeptide molecules—homologue recombination method by Schulga, Alexey A., Levichkin, llya V., Kurbanov, Feruz T., Lokorokov, Andrei L., Pozmogova, Galina E., Kirpichnikov, Mikhail P.

“…Mapping of functionally important sites (FIS) is a problem of great importance in the study of protein molecules. Success in gene cloning and enlargement of…”
Get full text