Search Results - "G. A. Wilson"

Multifunctional agriculture: a transition theory perspective by Wilson, G. A

“…In a time of great agricultural and rural change, the notion of 'multifunctionality' has remained under-theorized and poorly linked to wider debates in the…”
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Medical student attitudes towards older people: a critical review of quantitative measures by Wilson, Mark A G, Kurrle, Susan, Wilson, Ian

“…Further research into medical student attitudes towards older people is important, and requires accurate and detailed evaluative methodology. The two…”
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Addressing the health disadvantage of rural populations: How does epidemiological evidence inform rural health policies and research? by Smith, Karly B., Humphreys, John S., Wilson, Murray G. A.

“…We reviewed evidence of any apparently significant ‘rural‐urban’ health status differentials in developed countries, to determine whether such differentials…”
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Brief Report: Identification of BACH2 and RAD51B as Rheumatoid Arthritis Susceptibility Loci in a Meta‐Analysis of Genome‐Wide Data by McAllister, Kate, Yarwood, Annie, Bowes, John, Orozco, Gisela, Viatte, Sebastian, Diogo, Dorothée, Hocking, Lynne J., Steer, Sophia, Wordsworth, Paul, Wilson, A. G., Morgan, Ann W., Kremer, Joel M., Pappas, Dimitrios, Gregersen, Peter, Klareskog, Lars, Plenge, Robert, Barton, Anne, Greenberg, Jeffrey, Worthington, Jane, Eyre, Stephen

“…Objective A recent high‐density fine‐mapping (ImmunoChip) study of genetic associations in rheumatoid arthritis (RA) identified 14 risk loci with validated…”
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Investigating CD11c expression as a potential genomic biomarker of response to TNF inhibitor biologics in whole blood rheumatoid arthritis samples by Smith, Samantha Louise, Eyre, Stephen, Yarwood, Annie, Hyrich, Kimme, Morgan, Ann W, Wilson, A G, Isaacs, John, Plant, Darren, Barton, Anne

“…Gene expression profiling is rapidly becoming a useful and informative tool in a much needed area of research. Identifying patients as to whether they will…”
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Identification of novel FLT‐3 Asp835 mutations in adult acute myeloid leukaemia by Abu‐Duhier, F. M., Goodeve, A. C., Wilson, G. A., Care, R. S., Peake, I. R., Reilly, J. T.

“…Genomic DNA from 97 cases of adult de novo acute myeloid leukaemia (AML) was screened using polymerase chain reaction (PCR) and conformation‐sensitive gel…”
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Orphans as taxonomically restricted and ecologically important genes by Wilson, G A, Bertrand, N, Patel, Y, Hughes, J B, Feil, E J, Field, D

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Genome-wide association meta-analyses to identify common genetic variants associated with hallux valgus in Caucasian and African Americans by Hsu, Yi-Hsiang, Liu, Youfang, Hannan, Marian T, Maixner, William, Smith, Shad B, Diatchenko, Luda, Golightly, Yvonne M, Menz, Hylton B, Kraus, Virginia B, Doherty, Michael, Wilson, A G, Jordan, Joanne M

“…Hallux valgus (HV) affects ∼36% of Caucasian adults. Although considered highly heritable, the underlying genetic determinants are unclear. We conducted the…”
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A spectrum of susceptibility to rheumatoid arthritis within HLA-DRB1: stratification by autoantibody status in a large UK population by Mackie, S L, Taylor, J C, Martin, S G, Wordsworth, P, Steer, S, Wilson, A G, Worthington, J, Emery, P, Barrett, J H, Morgan, A W

“…Previously-proposed rheumatoid arthritis (RA) HLA-DRB1 susceptibility and protective models were compared, based on amino acids at positions 67–74 and…”
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Genetic influences modulating the radiological severity of rheumatoid arthritis by Marinou, I, Maxwell, J R, Wilson, A G

“…This review focuses on the contribution of genetic markers to the severity of radiological damage in rheumatoid arthritis (RA). Currently available biomarkers…”
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Contemporary gene flow and the spatio‐temporal genetic structure of subdivided newt populations (Triturus cristatus, T. marmoratus) by JEHLE, R., WILSON, G. A., ARNTZEN, J. W., BURKE, T.

“…Gene flow and drift shape the distribution of neutral genetic diversity in metapopulations, but their local rates are difficult to quantify. To identify gene…”
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A gain of function polymorphism in the interleukin 6 receptor influences RA susceptibility by Marinou, I, Walters, K, Winfield, J, Bax, D E, Wilson, A G

“…To investigate the possible role of a functional polymorphism in the soluble interleukin 6 receptor (sIL-6R) gene in the genetic background of rheumatoid…”
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The Mal/TIRAP S180L and TLR4 G299D polymorphisms are not associated with susceptibility to, or severity of, rheumatoid arthritis by Sheedy, F J, Marinou, I, O'Neill, L A J, Wilson, A G

“…Toll-like receptors (TLRs), including TLR4, have been implicated in the pathogenesis of rheumatoid arthritis (RA). Signalling by these receptors involves…”
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FLT3 internal tandem duplication mutations in adult acute myeloid leukaemia define a high-risk group by ABU-DUHIER, F. M, GOODEVE, A. C, WILSON, G. A, GARI, M. A, PEAKE, I. R, REES, D. C, VANDENBERGHE, E. A, WINSHIP, P. R, REILLY, J. T

“…Genomic DNA from 106 cases of adult de novo acute myeloid leukaemia (AML) was screened by polymerase chain reaction (PCR) and gel electrophoresis for FLT3…”
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A genetic variant in granzyme B is associated with progression of joint destruction in rheumatoid arthritis by Knevel, R., Krabben, A., Wilson, A. G., Brouwer, E., Leijsma, M. K., Lindqvist, E., de Rooy, D. P. C., Daha, N. A., van der Linden, M. P. M., Tsonaka, S., Zhernakova, A., Westra, H.‐J., Franke, L., Houwing‐Duistermaat, J. J., Toes, R. E. M., Huizinga, T. W. J., Saxne, T., van der Helm‐van Mil, A. H. M.

“…Objective Genetic factors account for an estimated 45–58% of the variance in joint destruction in rheumatoid arthritis (RA). The serine proteinase granzyme B…”
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Interleukin gene polymorphisms and breast cancer: a case control study and systematic literature review by Balasubramanian, S P, Azmy, I A F, Higham, S E, Wilson, A G, Cross, S S, Cox, A, Brown, N J, Reed, M W

“…Interleukins and cytokines play an important role in the pathogenesis of many solid cancers. Several single nucleotide polymorphisms (SNPs) identified in…”
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Association between radiographic severity of rheumatoid arthritis and shared epitope alleles: differing mechanisms of susceptibility and protection by Mewar, D, Marinou, I, Coote, A L, Moore, D J, Akil, M, Smillie, D, Dickson, M C, Binks, M H, Montgomery, D S, Wilson, A G

“…To investigate the association of a recently described classification of Human leukocyte antigen (HLA)-DRB1 shared epitope alleles with rheumatoid factors (RF)…”
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Geodemographics and spatial interaction: an integrated model for higher education by Singleton, A. D., Wilson, A. G., O’Brien, O.

“…Spatial interaction modelling and geodemographic analysis have each developed as quite separate research traditions. In this paper, we present an integrated…”
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Toll-like receptors: their role in allergy and non-allergic inflammatory disease by Sabroe, I., Parker, L. C., Wilson, A. G., Whyte, M. K. B., Dower, S. K.

“…Summary The human TLRs comprise an important and interesting group of receptors that regulate pathogen‐related responses, and play as yet uncharacterized roles…”
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Detection of ubiquitous and heterogeneous mutations in cell-free DNA from patients with early-stage non-small-cell lung cancer by Jamal-Hanjani, M., Wilson, G.A., Horswell, S., Mitter, R., Sakarya, O., Constantin, T., Salari, R., Kirkizlar, E., Sigurjonsson, S., Pelham, R., Kareht, S., Zimmermann, B., Swanton, C.

“…The aim of this pilot study was to assess whether both ubiquitous and heterogeneous somatic mutations could be detected in cell-free DNA (cfDNA) from patients…”
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