Search Results - "G Singal, Amit"

Surveillance for Hepatocellular Carcinoma: Current Best Practice and Future Direction by Kanwal, Fasiha, Singal, Amit G.

“…Hepatocellular cancer (HCC) is the fourth leading cause of cancer-related deaths worldwide and the fastest growing cause of cancer deaths in the United States…”
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Epidemiology and surveillance for hepatocellular carcinoma: New trends by Singal, Amit G., Lampertico, Pietro, Nahon, Pierre

“…The burden of hepatocellular carcinoma (HCC) is highest in East Asia and Africa, although its incidence and mortality are rapidly rising in the United States…”
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Contemporary Epidemiology of Chronic Liver Disease and Cirrhosis by Moon, Andrew M., Singal, Amit G., Tapper, Elliot B.

“…Accurate estimates for the contemporary burden of chronic liver disease (CLD) are vital for setting clinical, research, and policy priorities. We aimed to…”
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Early detection, curative treatment, and survival rates for hepatocellular carcinoma surveillance in patients with cirrhosis: a meta-analysis by Singal, Amit G, Pillai, Anjana, Tiro, Jasmin

“…Surveillance for hepatocellular carcinoma (HCC) has level I evidence among patients with hepatitis B but only level II evidence in patients with cirrhosis…”
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Breakthroughs in Hepatocellular Carcinoma Therapies by Singal, Amit G., Kudo, Masatoshi, Bruix, Jordi

“…Several breakthroughs in hepatocellular carcinoma (HCC) therapy across tumor stages provide hope to improve its dismal prognosis. Although surgical and local…”
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BCLC strategy for prognosis prediction and treatment recommendation: The 2022 update by Reig, Maria, Forner, Alejandro, Rimola, Jordi, Ferrer-Fàbrega, Joana, Burrel, Marta, Garcia-Criado, Ángeles, Kelley, Robin K., Galle, Peter R., Mazzaferro, Vincenzo, Salem, Riad, Sangro, Bruno, Singal, Amit G., Vogel, Arndt, Fuster, Josep, Ayuso, Carmen, Bruix, Jordi

“…There have been major advances in the armamentarium for hepatocellular carcinoma (HCC) since the last official update of the Barcelona Clinic Liver Cancer…”
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AGA Clinical Practice Update on Interaction Between Oral Direct-Acting Antivirals for Chronic Hepatitis C Infection and Hepatocellular Carcinoma: Expert Review by Singal, Amit G., Lim, Joseph K., Kanwal, Fasiha

“…The purpose of this clinical practice update is to evaluate the evidence describing the interaction between direct-acting antiviral (DAA) therapy for hepatitis…”
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AASLD Practice Guidance on prevention, diagnosis, and treatment of hepatocellular carcinoma by Singal, Amit G, Llovet, Josep M, Yarchoan, Mark, Mehta, Neil, Heimbach, Julie K, Dawson, Laura A, Jou, Janice H, Kulik, Laura M, Agopian, Vatche G, Marrero, Jorge A, Mendiratta-Lala, Mishal, Brown, Daniel B, Rilling, William S, Goyal, Lipika, Wei, Alice C, Taddei, Tamar H

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Downstaging hepatocellular carcinoma: A systematic review and pooled analysis by Parikh, Neehar D., Waljee, Akbar K., Singal, Amit G.

“…Downstaging can facilitate liver transplantation (LT) for patients outside of Milan criteria with hepatocellular carcinoma (HCC); however, the optimal protocol…”
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Cost-Effectiveness of Hepatocellular Carcinoma Surveillance: An Assessment of Benefits and Harms by Parikh, Neehar D., Singal, Amit G., Hutton, David W., Tapper, Elliot B.

“…The value of hepatocellular carcinoma (HCC) surveillance is defined by the balance of benefits, i.e., early tumor detection, and potential harms, related to…”
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Racial and Ethnic Disparities in Nonalcoholic Fatty Liver Disease Prevalence, Severity, and Outcomes in the United States: A Systematic Review and Meta-analysis by Rich, Nicole E., Oji, Stefany, Mufti, Arjmand R., Browning, Jeffrey D., Parikh, Neehar D., Odewole, Mobolaji, Mayo, Helen, Singal, Amit G.

“…Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in the United States, affecting 75–100 million Americans. However, the…”
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Short term use of oral corticosteroids and related harms among adults in the United States: population based cohort study by Waljee, Akbar K, Rogers, Mary A M, Lin, Paul, Singal, Amit G, Stein, Joshua D, Marks, Rory M, Ayanian, John Z, Nallamothu, Brahmajee K

“…Objective To determine the frequency of prescriptions for short term use of oral corticosteroids, and adverse events (sepsis, venous thromboembolism,…”
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Accuracy of the Liver Imaging Reporting and Data System in Computed Tomography and Magnetic Resonance Image Analysis of Hepatocellular Carcinoma or Overall Malignancy—A Systematic Review by van der Pol, Christian B., Lim, Christopher S., Sirlin, Claude B., McGrath, Trevor A., Salameh, Jean-Paul, Bashir, Mustafa R., Tang, An, Singal, Amit G., Costa, Andreu F., Fowler, Kathryn, McInnes, Matthew D.F.

“…The Liver Imaging Reporting and Data System (LI-RADS) categorizes observations from imaging analyses of high-risk patients based on the level of suspicion for…”
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Hepatocellular carcinoma tumour markers: Current role and expectations by Rich, Nicole, M.D, Singal, Amit G., M.D., M.S

“…Abstract Tumour markers could be helpful along the continuum of care for patients with hepatocellular carcinoma; however, there is insufficient data for…”
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Somatic Mutations Increase Hepatic Clonal Fitness and Regeneration in Chronic Liver Disease by Zhu, Min, Lu, Tianshi, Jia, Yuemeng, Luo, Xin, Gopal, Purva, Li, Lin, Odewole, Mobolaji, Renteria, Veronica, Singal, Amit G., Jang, Younghoon, Ge, Kai, Wang, Sam C., Sorouri, Mahsa, Parekh, Justin R., MacConmara, Malcolm P., Yopp, Adam C., Wang, Tao, Zhu, Hao

“…Normal tissues accumulate genetic changes with age, but it is unknown if somatic mutations promote clonal expansion of non-malignant cells in the setting of…”
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The effect of PNPLA3 on fibrosis progression and development of hepatocellular carcinoma: a meta-analysis by Singal, Amit G, Manjunath, Hema, Yopp, Adam C, Beg, Muhammad S, Marrero, Jorge A, Gopal, Purva, Waljee, Akbar K

“…The PNPLA3 rs738409 single-nucleotide polymorphism is known to promote nonalcoholic steatohepatitis (NASH), but its association with fibrosis severity and…”
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Clinical Evaluation of the Abbott Alinity SARS-CoV-2 Spike-Specific Quantitative IgG and IgM Assays among Infected, Recovered, and Vaccinated Groups by Narasimhan, Madhusudhanan, Mahimainathan, Lenin, Araj, Ellen, Clark, Andrew E, Markantonis, John, Green, Allen, Xu, Jing, SoRelle, Jeffrey A, Alexis, Charles, Fankhauser, Kimberly, Parikh, Hiren, Wilkinson, Kathleen, Reczek, Annika, Kopplin, Noa, Yekkaluri, Sruthi, Balani, Jyoti, Thomas, Abey, Singal, Amit G, Sarode, Ravi, Muthukumar, Alagarraju

“…The coronavirus disease 19 (COVID-19) pandemic continues to impose a significant burden on global health infrastructure. While identification and containment…”
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International Liver Cancer Association (ILCA) White Paper on Biomarker Development for Hepatocellular Carcinoma by Singal, Amit G., Hoshida, Yujin, Pinato, David J., Marrero, Jorge, Nault, Jean-Charles, Paradis, Valerie, Tayob, Nabihah, Sherman, Morris, Lim, Young Suk, Feng, Ziding, Lok, Anna S., Rinaudo, Jo Ann, Srivastava, Sudhir, Llovet, Josep M., Villanueva, Augusto

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Systematic review: radiomics for the diagnosis and prognosis of hepatocellular carcinoma by Harding‐Theobald, Emily, Louissaint, Jeremy, Maraj, Bharat, Cuaresma, Edward, Townsend, Whitney, Mendiratta‐Lala, Mishal, Singal, Amit G., Su, Grace L., Lok, Anna S., Parikh, Neehar D.

“…Summary Background Advances in imaging technology have the potential to transform the early diagnosis and treatment of hepatocellular carcinoma (HCC) through…”
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A primer on effectiveness and efficacy trials by Singal, Amit G, Higgins, Peter D R, Waljee, Akbar K

“…Although efficacy and effectiveness studies are both important when evaluating interventions, they serve distinct purposes and have different study designs…”
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