Search Results - "G Raghu, K."

Endoplasmic reticulum stress: A master regulator of metabolic syndrome by Mohan, Sreelekshmi, R, Preetha Rani M., Brown, Lindsay, Ayyappan, Prathapan, G, Raghu K.

“…Endoplasmic reticulum (ER) stress, a change in the ER homeostasis, leads to initiation of the unfolded protein response (UPR). The primary functions of the UPR…”
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Pretreatment of hydroethanolic extract of Dillenia indica L. attenuates oleic acid induced NAFLD in HepG2 cells via modulating SIRT-1/p-LKB-1/AMPK, HMGCR & PPAR-α signaling pathways by Poornima, M.S., Sindhu, G., Billu, Abraham, Sruthi, C.R., Nisha, P., Gogoi, Pinku, Baishya, Gakul, G Raghu, K.

“…Dillenia indica L. is an edible plant from the Dilleniaceae family present in the forest of India and other Asian countries. Different parts of this plant are…”
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In vitro antioxidant and inhibitory potential of Terminalia bellerica and Emblica officinalis fruits against LDL oxidation and key enzymes linked to type 2 diabetes by Nampoothiri, Suresh V., Prathapan, A., Cherian, Ozhathil Lijo, Raghu, K.G., Venugopalan, V.V., Sundaresan, A.

“…The present study evaluated the free radical scavenging capacity and antioxidant potential of different solvent extracts (Hexane (HE), ethyl acetate (EA),…”
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Fructose-palmitate based high calorie induce steatosis in HepG2 cells via mitochondrial dysfunction: An in vitro approach by Swapna Sasi, U S, Sindhu, G, Raghu, K.G.

“…A proper in vitro model for conducting research on high energy food induced steatosis via defective energy metabolism in the liver is not visible in the…”
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A novel aureothin diepoxide derivative from Streptomyces sp. NIIST-D31 strain by Drissya, Thankappan, Induja, D. K., Poornima, M. S., Jesmina, A. R. S., Prabha, Bernard, Saumini, Mathew, Suresh, Cherumuttathu H., Raghu, K. G., Kumar, B. S. Dileep, Lankalapalli, Ravi S.

“…A novel vicinal diepoxide of alloaureothin was isolated from Streptomyces sp. NIIST-D31 strain along with three carboxamides, p -aminobenzoic acid and…”
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Effect of heat treatment on curcuminoid, colour value and total polyphenols of fresh turmeric rhizome by Prathapan, A, Lukhman, M, Arumughan, C, Sundaresan, A, Raghu, K.G

“…Studies were undertaken to examine the effect of heat treatment on total phenolic content (TPC), colour value (yellowishness and brightness), polyphenol…”
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Bilobalide abates inflammation, insulin resistance and secretion of angiogenic factors induced by hypoxia in 3T3-L1 adipocytes by controlling NF-κB and JNK activation by Priyanka, A, Sindhu, G, Shyni, GL, Preetha Rani, MR, Nisha, VM, Raghu, KG

“…Obesity leads to inflammation and insulin resistance in adipose tissue. Hypoxia, observed in obese adipose tissue is suggested as a major cause of inflammation…”
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Boerhaavia diffusa L. attenuates angiotensin II-induced hypertrophy in H9c2 cardiac myoblast cells via modulating oxidative stress and down-regulating NF-κβ and transforming growth factor β1 by PRATHAPAN, A, VINEETHA, V. P, ABHILASH, P. A, RAGHU, K. G

“…The present study evaluated the antihypertrophic potential of the ethanolic extract of Boerhaavia diffusa (BDE), a well-known edible cardiotonic plant reported…”
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Apigenin and Quercetin Ameliorate Mitochondrial Alterations by Tunicamycin-Induced ER Stress in 3T3-L1 Adipocytes by Nisha, V. M, Anusree, S. S, Priyanka, A, Raghu, K. G

“…Endoplasmic reticulum (ER) is an important organelle with functions like protein synthesis, folding, and calcium homeostasis. ER stress, a condition that…”
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Glucotoxicity results in apoptosis in H9c2 cells via alteration in redox homeostasis linked mitochondrial dynamics and polyol pathway and possible reversal with cinnamic acid by Anupama, Nair, Preetha Rani, M.R., Shyni, G.L., Raghu, K.G.

“…Several mechanisms have been proposed for the heart dysfunction during hyperglycemia. The aim of the present in vitro study is to elucidate the role of…”
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Polyphenol rich fruit pulp of Aegle marmelos (L.) Correa exhibits nutraceutical properties to down regulate diabetic complications — An in vitro study by Prathapan, A., Krishna, Mahesh S., Nisha, V.M., Sundaresan, A., Raghu, K.G.

“…In the present study, methanolic extract of Aegle marmelos (L.) Correa fruit pulp (AME) was evaluated for various parameters relevant to diabetes such as…”
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An in vitro study reveals the nutraceutical potential of punicic acid relevant to diabetes via enhanced GLUT4 expression and adiponectin secretion by Anusree, S S, Priyanka, A, Nisha, V M, Das, Arya A, Raghu, K G

“…The prevalence of diabetes and heart diseases is increasing in the world. Nutraceuticals of natural origin are gaining importance as an alternative to modern…”
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Arsenic Trioxide Toxicity in H9c2 Myoblasts—Damage to Cell Organelles and Possible Amelioration with Boerhavia diffusa by Vineetha, V. P., Prathapan, A., Soumya, R. S., Raghu, K. G.

“…Arsenic trioxide (ATO) has been long used as a chemotherapeutic agent because of its significant anticancer property. Unfortunately, the use of ATO is limited…”
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Isolation and Identification of α-Glucosidase and Protein Glycation Inhibitors from Stereospermum colais by Rani, M. Priya, Raghu, K. G., Nair, Mangalam S., Padmakumari, K. P.

“…Stereospermum colais (family Bignoniaceae) is a well-known pharmacologically potent medicinal plant reported in traditional systems of medicine. Phytochemical…”
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Methylglyoxal induces ambience for cancer promotion in HepG2 cells via Warburg effect and promotes glycation by Sruthi, C R, Raghu, K. G.

“…Methylglyoxal (MGO) is a toxic, highly reactive metabolite derived mainly from glucose and amino acids degradation. MGO is also one of the prime precursors for…”
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Impact of COVID-19 on the Cardiovascular System: A Review of Available Reports by Soumya, R. S., Unni, T. Govindan, Raghu, K. G.

“…The recent emergence of the coronavirus disease 19 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in China is now a global…”
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Green, Nonchemical Route for the Synthesis of ZnO Superstructures, Evaluation of Its Applications toward Photocatalysis, Photoluminescence, and Biosensing by Udayabhanu, Nagaraju, G, Nagabhushana, H, Basavaraj, R. B, Raghu, G. K, Suresh, D, Rajanaika, H, Sharma, S. C

“…In the present work, we have developed a novel, ecofriendly method for the synthesis of ZnO superstructures for the first time through the thermal…”
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Vanillic acid mitigates hyperinsulinemia induced ER stress mediated altered calcium homeostasis, MAMs distortion and surplus lipogenesis in HepG2 cells by Mohan, Sreelekshmi, Nair, Anupama, Poornima, M.S., Raghu, K.G.

“…Hyperinsulinemia (HI) induced insulin resistance (IR) and associated pathologies are the burning and unsolvable issues in diabetes treatment. The cellular,…”
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Current and novel therapeutic targets in the treatment of rheumatoid arthritis by George, Genu, Shyni, G. L., Raghu, K. G.

“…Rheumatoid arthritis (RA), a multifactorial disease characterized by synovitis, cartilage destruction, bone erosion, and periarticular decalcification, finally…”
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Advanced glycation end products and their adverse effects: The role of autophagy by Sruthi, C. R., Raghu, K. G.

“…The critical roles played by advanced glycation endproducts (AGEs) accumulation in diabetes and diabetic complications have gained intense recognition. AGEs…”
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