Search Results - "G Nader"
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Pharmacological and Clinical Aspects of Heme Oxygenase
Published in Pharmacological reviews (01-03-2008)“…This review is intended to stimulate interest in the effect of increased expression of heme oxygenase-1 (HO-1) protein and increased levels of HO activity on…”
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Modulation of Nrf2/ARE Pathway by Food Polyphenols: A Nutritional Neuroprotective Strategy for Cognitive and Neurodegenerative Disorders
Published in Molecular neurobiology (01-10-2011)“…In recent years, there has been a growing interest, supported by a large number of experimental and epidemiological studies, for the beneficial effects of some…”
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HO-1 overexpression and underexpression: Clinical implications
Published in Archives of biochemistry and biophysics (30-09-2019)“…In this review we examine the effects of both over- and under-production of heme oxygenase-1 (HO-1) and HO activity on a broad spectrum of biological systems…”
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Translational Significance of Heme Oxygenase in Obesity and Metabolic Syndrome
Published in Trends in pharmacological sciences (Regular ed.) (01-01-2016)“…The global epidemic of obesity continues unabated with sequelae of diabetes and metabolic syndrome. This review reflects the dramatic increase in research on…”
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Regulation of diabetic cardiomyopathy by caloric restriction is mediated by intracellular signaling pathways involving 'SIRT1 and PGC-1α'
Published in Cardiovascular diabetology (02-08-2018)“…Metabolic disorders such as obesity, insulin resistance and type 2 diabetes mellitus (DM2) are all linked to diabetic cardiomyopathy that lead to heart…”
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Fructose Mediated Non-Alcoholic Fatty Liver Is Attenuated by HO-1-SIRT1 Module in Murine Hepatocytes and Mice Fed a High Fructose Diet
Published in PloS one (22-06-2015)“…Oxidative stress underlies the etiopathogenesis of nonalcoholic fatty liver disease (NAFLD), obesity and cardiovascular disease (CVD). Heme Oxygenase-1 (HO-1)…”
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Epoxyeicosatrienoic Acid as Therapy for Diabetic and Ischemic Cardiomyopathy
Published in Trends in pharmacological sciences (Regular ed.) (01-11-2016)“…Cardiovascular disease remains the leading cause of death worldwide. Among many potential targets for pharmacological intervention, a promising strategy…”
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The nucleus acts as a ruler tailoring cell responses to spatial constraints
Published in Science (American Association for the Advancement of Science) (16-10-2020)“…The microscopic environment inside a metazoan organism is highly crowded. Whether individual cells can tailor their behavior to the limited space remains…”
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The Peroxisome Proliferator-Activated Receptor-Gamma Coactivator-1α-Heme Oxygenase 1 Axis, a Powerful Antioxidative Pathway with Potential to Attenuate Diabetic Cardiomyopathy
Published in Antioxidants & redox signaling (10-06-2020)“…From studies of diabetic animal models, the downregulation of peroxisome proliferator-activated receptor-gamma coactivator-1α (PGC-1α)-heme oxygenase 1 (HO-1)…”
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Heme-oxygenase and lipid mediators in obesity and associated cardiometabolic diseases: Therapeutic implications
Published in Pharmacology & therapeutics (Oxford) (01-03-2022)“…Obesity-mediated metabolic syndrome remains the leading cause of death worldwide. Among many potential targets for pharmacological intervention, a promising…”
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Resistance exercise training modulates acute gene expression during human skeletal muscle hypertrophy
Published in Journal of applied physiology (1985) (15-03-2014)“…We sought to determine whether acute resistance exercise (RE)-induced gene expression is modified by RE training. We studied the expression patterns of a…”
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Correction: Kavain Reduces Porphyromonas gingivalis –Induced Adipocyte Inflammation: Role of PGC-1α Signaling
Published in The Journal of immunology (1950) (01-11-2021)Get full text
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Kavain Reduces Porphyromonas gingivalis- Induced Adipocyte Inflammation: Role of PGC-1α Signaling
Published in The Journal of immunology (1950) (01-09-2018)“…A link between obesity and periodontitis has been suggested because of compromised immune response and chronic inflammation in obese patients. In this study,…”
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Real‐Time Neural Materials using Block‐Compressed Features
Published in Computer graphics forum (01-05-2024)“…Neural materials typically consist of a collection of neural features along with a decoder network. The main challenge in integrating such models in real‐time…”
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PGC-1 alpha regulates HO-1 expression, mitochondrial dynamics and biogenesis: Role of epoxyeicosatrienoic acid
Published in Prostaglandins & other lipid mediators (01-09-2016)“…Obesity is a risk factor in the development of type 2 diabetes mellitus (DM2), which is associated with increased morbidity and mortality, predominantly as a…”
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PARP-1 inhibition protects the diabetic heart through activation of SIRT1-PGC-1α axis
Published in Experimental cell research (15-12-2018)“…Type 2 diabetes mellitus (DM2) follows impaired glucose tolerance in obesity and is frequently associated with hypertension, causing adverse myocardial…”
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Heme oxygenase-1 induction improves cardiac function following myocardial ischemia by reducing oxidative stress
Published in PloS one (21-03-2014)“…Oxidative stress plays a key role in exacerbating diabetes and cardiovascular disease. Heme oxygenase-1 (HO-1), a stress response protein, is cytoprotective,…”
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Treatment of Obese Diabetic Mice With a Heme Oxygenase Inducer Reduces Visceral and Subcutaneous Adiposity, Increases Adiponectin Levels, and Improves Insulin Sensitivity and Glucose Tolerance
Published in Diabetes (New York, N.Y.) (01-06-2008)“…Treatment of Obese Diabetic Mice With a Heme Oxygenase Inducer Reduces Visceral and Subcutaneous Adiposity, Increases Adiponectin Levels, and Improves Insulin…”
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Autophagy guided interventions to modify the cardiac phenotype of Danon disease
Published in Biochemical pharmacology (01-10-2022)“…Lamp2 controls autophagy through autolysosome formation. Lamp2 mutations lead to accumulation of undegraded cellular debris. Autophagy may be modified by…”
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Cold Press Pomegranate Seed Oil Attenuates Dietary-Obesity Induced Hepatic Steatosis and Fibrosis through Antioxidant and Mitochondrial Pathways in Obese Mice
Published in International journal of molecular sciences (31-07-2020)“…Obesity is associated with metabolic syndrome, hypertension, dyslipidemia, nonalcoholic fatty liver disease (NAFLD), and type 2 diabetes. In this study, we…”
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