Search Results - "G N Phillips, Jr"

A Sampling Problem in Molecular Dynamics Simulations of Macromolecules by Clarage, James B., Romo, Tod, Andrews, B. Kim, Pettitt, B. Montgomery, Phillips, George N.

“…Correlations in low-frequency atomic displacements predicted by molecular dynamics simulations on the order of 1 ns are undersampled for the time scales…”
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The molecular structure of green fluorescent protein by Yang, Fan, Moss, Larry G, Phillips, George N

“…The crystal structure of recombinant wild-type green fluorescent protein (GFP) has been solved to a resolution of 1.9 A by multiwavelength anomalous dispersion…”
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Tropomyosin crystal structure and muscle regulation by Phillips, Jr, G N, Fillers, J P, Cohen, C

“…The crystal structure of tropomyosin filaments has been solved to 15 A resolution by refinement of models against the diffraction data and heavy atom labeling…”
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Molecular Structure of Dihydroorotase:  A Paradigm for Catalysis through the Use of a Binuclear Metal Center by Thoden, James B, Phillips, George N, Neal, Tamiko M, Raushel, Frank M, Holden, Hazel M

“…Dihydroorotase plays a key role in pyrimidine biosynthesis by catalyzing the reversible interconversion of carbamoyl aspartate to dihydroorotate. Here we…”
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Structure of myoglobin-ethyl isocyanide. Histidine as a swinging door for ligand entry by Johnson, K A, Olson, J S, Phillips, Jr, G N

“…The structure of myoglobin(Fe II)-ethyl isocyanide has been solved at 1.68 A resolution by X-ray crystallography. The isocyano group of the ligand is distorted…”
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Structure and dynamics of green fluorescent protein by Phillips, George N

“…Many marine organisms are luminescent. The proteins that produce the light include a primary light producer (aequorin or luciferase) and often a secondary…”
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Crystallization and preliminary X-ray diffraction analysis of 11 S acetylcholinesterase by Schrag, J D, Schmid, M F, Morgan, D G, Phillips, G N, Chiu, W, Tang, L

“…The 11 S form of acetylcholinesterase from Electrophorus electricus was purified by affinity chromatography. The protein was crystallized from polyethylene…”
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Crystal structure of photolysed carbonmonoxy-myoglobin by Schlichting, Ilme, Berendzen, Joel, Phillips, George N, Sweet, Robert M

“…Myoglobin is a globular haem protein that reversibly binds ligands such as O2 and CO. Single photons of visible light can break the covalent bond between CO…”
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A novel site-directed mutant of myoglobin with an unusually high O2 affinity and low autooxidation rate by T E Carver, R E Brantley, Jr, E W Singleton, R M Arduini, M L Quillin, G N Phillips, Jr, J S Olson

“…Mutants of sperm whale myoglobin were constructed at position 29 (B10 in helix notation) to examine the effects of distal pocket size on the rates of ligand…”
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Streptococcal M Protein: α -Helical Coiled-Coil Structure and Arrangement on the Cell Surface by Phillips, George N., Flicker, Paula F., Cohen, Carolyn, Manjula, Belur N., Fischetti, Vincent A.

“…The conformation and molecular dimensions of purified type 6 streptococcal M proteins establish the close structural relationship of these molecules to…”
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The closed conformation of a highly flexible protein: the structure of E. coli adenylate kinase with bound AMP and AMPPNP by Berry, M B, Meador, B, Bilderback, T, Liang, P, Glaser, M, Phillips, Jr, G N

“…The structure of E. coli adenylate kinase with bound AMP and AMPPNP at 2.0 A resolution is presented. The protein crystallizes in space group C2 with two…”
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Characterization of recombinant soybean leghemoglobin a and apolar distal histidine mutants by Hargrove, M.S, Barry, J.K, Brucker, E.A, Berry, M.B, Phillips, G.N. Jr, Olson, J.S, Arredondo-Peter, R, Dean, J.M, Klucas, R.V, Sarath, G

“…The cDNA for soybean leghemoglobin a (Lba) was cloned from a root nodule cDNA library and expressed in Escherichia coli. The crystal structure of the ferric…”
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Automatic identification of discrete substates in proteins: singular value decomposition analysis of time-averaged crystallographic refinements by Romo, T D, Clarage, J B, Sorensen, D C, Phillips, Jr, G N

“…The singular value decomposition (SVD) provides a method for decomposing a molecular dynamics trajectory into fundamental modes of atomic motion. The right…”
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Structure of co-crystals of tropomyosin and troponin by White, Steven P, Cohen, Carolyn, Phillips Jr, George N

“…Troponin, a Ca2+-sensitive complex, regulates the motions of tropomyosin on the thin filaments in many muscles. It has three subunits, each with a different…”
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Conformational variation of calcium-bound troponin C by Soman, Jayashree, Tao, Terence, Phillips Jr, George N.

“…Troponin is the Ca super(2+)-binding regulatory protein in mammalian skeletal and cardiac muscles. Together with tropomyosin, troponin regulates the…”
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Solution and crystal structures of a sperm whale myoglobin triple mutant that mimics the sulfide-binding hemoglobin from Lucina pectinata by Nguyen, B D, Zhao, X, Vyas, K, La Mar, G N, Lile, R A, Brucker, E A, Phillips, Jr, G N, Olson, J S, Wittenberg, J B

“…The bivalve mollusc Lucina pectinata harbors sulfide-oxidizing chemoautotrophic bacteria and expresses a monomeric hemoglobin I, HbI, with normal O2, but…”
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A new crystal form of tropomyosin. Preliminary X-ray diffraction analysis by Phillips, Jr, G N, Cohen, C, Stewart, M

“…A new crystalline form of tropomyosin has been produced that diffracts to about 4 A resolution. The crystals are grown at room temperature by slowly lowering…”
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High Resolution Crystal Structures of the Deoxy, Oxy, and Aquomet Forms of Cobalt Myoglobin by Brucker, Eric Allen, Olson, John S., Phillips, George N., Dou, Yi, Ikeda-Saito, Masao

“…The structures of the deoxy, oxy, and aquomet forms of native sperm whale myoglobin reconstituted with cobalt protoporphyrin IX have been determined by x-ray…”
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Crystallization and preliminary X-ray analysis of Escherichia coli adenylate kinase by Althoff, S, Zambrowicz, B, Liang, P, Glaser, M, Phillips, Jr, G N

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Crystallization and preliminary x-ray investigation of the regulatory subunit of cAMP-dependent protein kinase by Lee, J H, Bechtel, P J, Phillips, G N

“…Crystals of type I cAMP-dependent protein kinase regulatory subunit have been grown from solutions of ammonium sulfate. The crystals are square bipyramids,…”
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