Search Results - "Głowala‐Kosińska, Magdalena"

Transcriptome Analysis of Cells Exposed to Actinomycin D and Nutlin-3a Reveals New Candidate p53-Target Genes and Indicates That CHIR-98014 Is an Important Inhibitor of p53 Activity by Łasut-Szyszka, Barbara, Małachowska, Beata, Gdowicz-Kłosok, Agnieszka, Krześniak, Małgorzata, Głowala-Kosińska, Magdalena, Zajkowicz, Artur, Rusin, Marek

“…Co-treatment with actinomycin D and nutlin-3a (A + N) strongly activates p53. Previously we reported that CHIR-98014 (GSK-3 kinase inhibitor), acting in cells…”
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Novel role for the testis‐enriched HSPA2 protein in regulating epidermal keratinocyte differentiation by Gogler‐Pigłowska, Agnieszka, Klarzyńska, Katarzyna, Sojka, Damian R., Habryka, Anna, Głowala‐Kosińska, Magdalena, Herok, Marcin, Kryj, Mariusz, Halczok, Monika, Krawczyk, Zdzisław, Scieglinska, Dorota

“…HSPA2, a poorly characterized member of the HSPA (HSP70) chaperone family, is a testis‐enriched protein involved in male germ cell differentiation. Previously,…”
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Human Cardiac Mesenchymal Stromal Cells with CD105+CD34- Phenotype Enhance the Function of Post-Infarction Heart in Mice by Czapla, Justyna, Matuszczak, Sybilla, Wiśniewska, Ewa, Jarosz-Biej, Magdalena, Smolarczyk, Ryszard, Cichoń, Tomasz, Głowala-Kosińska, Magdalena, Śliwka, Joanna, Garbacz, Marcin, Szczypior, Mateusz, Jaźwiec, Tomasz, Langrzyk, Agnieszka, Zembala, Michał, Szala, Stanisław

“…The aim of the present study was to isolate mesenchymal stromal cells (MSC) with CD105+CD34- phenotype from human hearts, and to investigate their therapeutic…”
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Establishment and Characterization of the Novel High-Grade Serous Ovarian Cancer Cell Line OVPA8 by Tudrej, Patrycja, Olbryt, Magdalena, Zembala-Nożyńska, Ewa, Kujawa, Katarzyna A, Cortez, Alexander J, Fiszer-Kierzkowska, Anna, Pigłowski, Wojciech, Nikiel, Barbara, Głowala-Kosińska, Magdalena, Bartkowska-Chrobok, Aleksandra, Smagur, Andrzej, Fidyk, Wojciech, Lisowska, Katarzyna M

“…High-grade serous ovarian carcinoma (HGSOC) is the most frequent histological type of ovarian cancer and the one with worst prognosis. Unfortunately, the…”
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Association of circulating regulatory T cell number with the incidence and prognosis of diffuse large B-cell lymphoma by Głowala-Kosińska, Magdalena, Chwieduk, Agata, Nieckula, Jarosław, Saduś-Wojciechowska, Maria, Grosicki, Sebastian, Rusin, Aleksandra, Nowara, Elżbieta, Giebel, Sebastian

“…Regulatory T (Treg) cells are essential for maintaining immune tolerance. High Treg frequencies have been reported in peripheral blood and tissue samples of…”
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Anticancer effects of CAMEL peptide by Smolarczyk, Ryszard, Cichoń, Tomasz, Kamysz, Wojciech, Głowala-Kosińska, Magdalena, Szydło, Anna, Szultka, Łukasz, Sieroń, Aleksander L, Szala, Stanisław

“…This study analyzed whether therapy with CAMEL, an antimicrobial peptide (KWKLFKKIGAVLKVL), possess anticancer benefits. Although the peptide was cytotoxic for…”
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Strong activation of p53 by actinomycin D and nutlin-3a overcomes the resistance of cancer cells to the pro-apoptotic activity of the FAS ligand by Łasut-Szyszka, Barbara, Gdowicz-Kłosok, Agnieszka, Krześniak, Małgorzata, Głowala-Kosińska, Magdalena, Będzińska, Agnieszka, Rusin, Marek

“…The FAS ligand (FASLG) is expressed on lymphocytes, which employ it to activate death receptors on target cells. Cancer cells are generally resistant to…”
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Synergistic activation of p53 by actinomycin D and nutlin-3a is associated with the upregulation of crucial regulators and effectors of innate immunity by Krześniak, Małgorzata, Zajkowicz, Artur, Gdowicz-Kłosok, Agnieszka, Głowala-Kosińska, Magdalena, Łasut-Szyszka, Barbara, Rusin, Marek

“…Actinomycin D and nutlin-3a (A + N) activate p53, partly through induction of phosphorylation on Ser392. The death of A549 cells induced by A + N…”
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An Increase in HSF1 Expression Directs Human Mammary Epithelial Cells toward a Mesenchymal Phenotype by Vydra, Natalia, Toma-Jonik, Agnieszka, Janus, Patryk, Mrowiec, Katarzyna, Stokowy, Tomasz, Głowala-Kosińska, Magdalena, Sojka, Damian Robert, Olbryt, Magdalena, Widłak, Wiesława

“…HSF1 is a well-known heat shock protein expression regulator in response to stress. It also regulates processes important for growth, development or…”
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Evaluation of proinflammatory and immunosuppressive cytokines in blood and bone marrow of healthy hematopoietic stem cell donors by Fidyk, Wojciech, Mitrus, Iwona, Ciomber, Agnieszka, Smagur, Andrzej, Chwieduk, Agata, Głowala-Kosińska, Magdalena, Giebel, Sebastian

“…•The first study comparing cytokine concentration, expression of CD47 and CD274 immunosuppressive proteins on HSCs in bone marrow and blood of hematopoietic…”
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HSPA2 Chaperone Contributes to the Maintenance of Epithelial Phenotype of Human Bronchial Epithelial Cells but Has Non-Essential Role in Supporting Malignant Features of Non-Small Cell Lung Carcinoma, MCF7, and HeLa Cancer Cells by Sojka, Damian Robert, Gogler-Pigłowska, Agnieszka, Klarzyńska, Katarzyna, Klimczak, Marta, Zylicz, Alicja, Głowala-Kosińska, Magdalena, Krawczyk, Zdzisław, Scieglinska, Dorota

“…Heat Shock Protein A2 (HSPA2) is a member of the HSPA (HSP70) chaperone family and has a critical role for male fertility. HSPA2 is present in a number of…”
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Synthetic conjugates of genistein affecting proliferation and mitosis of cancer cells by Rusin, Aleksandra, Zawisza-Puchałka, Jadwiga, Kujawa, Katarzyna, Gogler-Pigłowska, Agnieszka, Wietrzyk, Joanna, Świtalska, Marta, Głowala-Kosińska, Magdalena, Gruca, Aleksandra, Szeja, Wiesław, Krawczyk, Zdzisław, Grynkiewicz, Grzegorz

“…This paper describes the synthesis and antiproliferative activity of conjugates of genistein (1) and unsaturated pyranosides. Constructs linking genistein with…”
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Synthesis and antiproliferative properties of ibuprofen–oligo(3-hydroxybutyrate) conjugates by Zawidlak-Węgrzyńska, Barbara, Kawalec, Michał, Bosek, Izabela, Łuczyk-Juzwa, Maria, Adamus, Grażyna, Rusin, Aleksandra, Filipczak, Piotr, Głowala-Kosińska, Magdalena, Wolańska, Katarzyna, Krawczyk, Zdzisław, Kurcok, Piotr

“…Synthesis of novel conjugates of the non-steroidal anti-inflammatory drug – ibuprofen with nontoxic oligo(3-hydroxybutyrate) (OHB) is described. Presented…”
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Unsaturated genistein disaccharide glycoside as a novel agent affecting microtubules by Rusin, Aleksandra, Gogler, Agnieszka, Głowala-Kosińska, Magdalena, Bochenek, Daria, Gruca, Aleksandra, Grynkiewicz, Grzegorz, Zawisza, Jadwiga, Szeja, Wiesław, Krawczyk, Zdzisław

“…Novel genistein derivative 7- O-(2,3,4,6-tetra- O-acetyl-β- d-galactopyranosyl)-(1→4)-(6- O-acetyl-hex-2-ene-α- d-erythropyranosyl) genistein, shortly named…”
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Nutlin-3a, an MDM2 antagonist and p53 activator, helps to preserve the replicative potential of cancer cells treated with a genotoxic dose of resveratrol by Zajkowicz, Artur, Krześniak, Małgorzata, Matuszczyk, Iwona, Głowala-Kosińska, Magdalena, Butkiewicz, Dorota, Rusin, Marek

“…Resveratrol is a natural compound that has been intensely studied due to its role in cancer prevention and potential as an anti-cancer therapy. Its effects…”
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High resolution proton nuclear magnetic resonance (1H NMR) spectroscopy of surviving C6 glioma cells after X-ray irradiation by Matulewicz, Lukasz, Cichoń, Anna, Sokół, Maria, Przybyszewski, Waldemar, Głowala-Kosińska, Magdalena, Gibas, Mirosław

“…To study biochemical response of living model of glioma to X-rays irradiation using high resolution proton nuclear magnetic resonance (1H NMR) spectroscopy…”
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Thymic Activity and T Cell Repertoire Recovery after Autologous Hematopoietic Stem Cell Transplantation Preceded by Myeloablative Radiotherapy or Chemotherapy by Głowala-Kosińska, Magdalena, Chwieduk, Agata, Smagur, Andrzej, Fidyk, Wojciech, Najda, Jacek, Mitrus, Iwona, Giebel, Sebastian

“…Abstract It was previously postulated that pretransplant myeloablative treatment may impair thymopoiesis, contributing in this way to delayed reconstitution of…”
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Very high efficacy of intermediate-dose cytarabine in combination with G-CSF as a second-line mobilization of hematopoietic stem cells by Kruzel, Tomasz, Sadus-Wojciechowska, Maria, Najda, Jacek, Czerw, Tomasz, Glowala-Kosinska, Magdalena, Holowiecki, Jerzy, Giebel, Sebastian

“…Issue Title: Including PIH Articles on How to improve the outcome of adult acute myeloid leukemia?…”
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The impact of blood donation on bone marrow harvest efficiency by Mitrus, Iwona, Wilkiewicz, Marcin, Fidyk, Wojciech, Ciomber, Agnieszka, Smagur, Andrzej, Glowala-Kosinska, Magdalena, Chwieduk, Agata, Borzdzilowska, Paulina, Sobczyk-Kruszelnicka, Malgorzata, Mendrek, Wlodzimierz, Najda, Jacek, Czerw, Tomasz, Giebel, Sebastian

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Overexpression of Heat Shock Transcription Factor 1 enhances the resistance of melanoma cells to doxorubicin and paclitaxel by Vydra, Natalia, Toma, Agnieszka, Glowala-Kosinska, Magdalena, Gogler-Piglowska, Agnieszka, Widlak, Wieslawa

“…Heat Shock Transcription Factor 1 (HSF1) is activated under stress conditions. In turn, it induces expression of Heat Shock Proteins (HSPs), which are…”
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