Search Results - "GŁADKOWSKI, WITOLD"

Distigmasterol-Modified Acylglycerols as New Structured Lipids—Synthesis, Identification and Cytotoxicity by Rudzińska, Magdalena, Grudniewska, Aleksandra, Chojnacka, Anna, Gładkowski, Witold, Maciejewska, Gabriela, Olejnik, Anna, Kowalska, Katarzyna

“…Plant sterols, also referred as phytosterols, have been known as bioactive compounds which have cholesterol-lowering properties in human blood. It has been…”
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Lipase-mediated Baeyer–Villiger oxidation of benzylcyclopentanones in ester solvents and deep eutectic solvents by Mazur, Marcelina, Janeczko, Tomasz, Gładkowski, Witold

“…This work presents the chemo-enzymatic Baeyer–Villiger oxidation of α-benzylcyclopentanones in ester solvents as well as deep eutectic solvents (DES). In the…”
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Production of erythritol and mannitol by Yarrowia lipolytica yeast in media containing glycerol by Tomaszewska, Ludwika, Rywińska, Anita, Gładkowski, Witold

“…Glycerol is a by-product generated in large amounts during the production of biofuels. This study presents an alternative means of crude glycerol valorization…”
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Lipase-Catalyzed Transesterification of Egg-Yolk Phophatidylcholine with Concentrate of n-3 Polyunsaturated Fatty Acids from Cod Liver Oil by Chojnacka, Anna, Gładkowski, Witold, Grudniewska, Aleksandra

“…Phospholipids containing PUFAs are important vehicles for their delivering to the targeted tissues. In our research project we established enzymatic methods…”
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Production of Structured Phosphatidylcholine with High Content of Myristic Acid by Lipase-Catalyzed Acidolysis and Interesterification by Anna Chojnacka, Witold Gładkowski

“…Synthesis of structured phosphatidylcholine (PC) enriched with myristic acid (MA) was conducted by acidolysis and interesterification reactions using…”
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Chalcone-Derived Lactones: Synthesis, Whole-Cell Biotransformation, and Evaluation of Their Antibacterial and Antifungal Activity by Gładkowski, Witold, Siepka, Monika, Żarowska, Barbara, Białońska, Agata, Gawdzik, Barbara, Urbaniak, Mariusz, Wawrzeńczyk, Czesław

“…Four compounds with lactone moiety were synthesized from chalcone in three- or four-step synthesis. γ-Bromo-δ-lactone was the only product of…”
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Isoprenoid-phospholipid conjugates as potential therapeutic agents: Synthesis, characterization and antiproliferative studies by Gliszczyńska, Anna, Niezgoda, Natalia, Gładkowski, Witold, Świtalska, Marta, Wietrzyk, Joanna

“…The aim of this research was to extend application field of isoprenoid compounds by their introduction into phospholipid structure as the transport vehicle…”
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Free and Immobilized Lecitase™ Ultra as the Biocatalyst in the Kinetic Resolution of ( E )-4-Arylbut-3-en-2-yl Esters by Leśniarek, Aleksandra, Chojnacka, Anna, Drozd, Radosław, Szymańska, Magdalena, Gładkowski, Witold

“…The influence of buffer type, co-solvent type, and acyl chain length was investigated for the enantioselective hydrolysis of racemic 4-arylbut-3-en-2-yl esters…”
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Acylglycerols of Myristic Acid as New Candidates for Effective Stigmasterol Delivery-Design, Synthesis, and the Influence on Physicochemical Properties of Liposomes by Gładkowski, Witold, Włoch, Aleksandra, Pruchnik, Hanna, Chojnacka, Anna, Grudniewska, Aleksandra, Wysota, Agnieszka, Dunal, Anna, Rubiano Castro, Daniel, Rudzińska, Magdalena

“…New carriers of phytosterols; acylglycerols containing natural myristic acid at -1 and -3 positions and stigmasterol residue linked to -2 position by carbonate…”
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Synthesis and Antimicrobial Activity of Methoxy- Substituted γ-Oxa-ε-lactones Derived from Flavanones by Gładkowski, Witold, Siepka, Monika, Janeczko, Tomasz, Kostrzewa-Susłow, Edyta, Popłoński, Jarosław, Mazur, Marcelina, Żarowska, Barbara, Łaba, Wojciech, Maciejewska, Gabriela, Wawrzeńczyk, Czesław

“…Six γ-oxa-ε-lactones, 4-phenyl-3,4-dihydro-2 -1,5-benzodioxepin-2-one ( ) and its five derivatives with methoxy groups in different positions of A and B rings…”
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Synthesis and Biological Evaluation of Novel Phosphatidylcholine Analogues Containing Monoterpene Acids as Potent Antiproliferative Agents by Gliszczyńska, Anna, Niezgoda, Natalia, Gładkowski, Witold, Czarnecka, Marta, Świtalska, Marta, Wietrzyk, Joanna

“…The synthesis of novel phosphatidylcholines with geranic and citronellic acids in sn-1 and sn-2 positions is described. The structured phospholipids were…”
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Methoxy-Substituted γ-Oxa-ε-Lactones Derived from Flavanones-Comparison of Their Anti-Tumor Activity In Vitro by Pawlak, Aleksandra, Henklewska, Marta, Hernández-Suárez, Beatriz, Siepka, Monika, Gładkowski, Witold, Wawrzeńczyk, Czesław, Motykiewicz-Pers, Karolina, Obmińska-Mrukowicz, Bożena

“…The study investigated four flavanone-derived γ-oxa-ε-lactones: a parent unsubstituted compound and its three derivatives with the methoxy group in positions…”
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Application of Lecitase® Ultra-Catalyzed Hydrolysis to the Kinetic Resolution of (E)-4-phenylbut-3-en-2-yl Esters by Aleksandra Leśniarek, Anna Chojnacka, Witold Gładkowski

“…The possibility of using Lecitase® Ultra as a novel alternative biocatalyst for the kinetic resolution of model racemic allyl esters of…”
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Enantiomeric trans β-aryl-δ-iodo-γ-lactones derived from 2,5-dimethylbenzaldehyde induce apoptosis in canine lymphoma cell lines by downregulation of anti-apoptotic Bcl-2 family members Bcl-xL and Bcl-2 by Pawlak, Aleksandra, Gładkowski, Witold, Kutkowska, Justyna, Mazur, Marcelina, Obmińska-Mrukowicz, Bożena, Rapak, Andrzej

“…[Display omitted] For many years, studies focused on developing new natural or synthetic compounds with antineoplastic activity have attracted the attention of…”
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Regio- and enantioselective microbial hydroxylation and evaluation of cytotoxic activity of β-cyclocitral-derived halolactones by Mazur, Marcelina, Gładkowski, Witold, Srček, Višnja Gaurina, Radošević, Kristina, Maciejewska, Gabriela, Wawrzeńczyk, Czesław

“…Three β-cyclocitral-derived halolactones, which exhibit antifeedant activity towards storage product pests, were subjected to microbial transformation…”
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Effect of Distigmasterol-Modified Acylglycerols on the Fluidity and Phase Transition of Lipid Model Membranes by Pruchnik, Hanna, Włoch, Aleksandra, Gładkowski, Witold, Grudniewska, Aleksandra, Chojnacka, Anna, Krzemiński, Mateusz, Rudzińska, Magdalena

“…Plant sterols are known for their health-promoting effects, lowering blood cholesterol levels and alleviating cardiovascular disease. In this work, we continue…”
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Conjugates of 1,3‐ and 1,2‐Acylglycerols with Stigmasterol: Synthesis, NMR Characterization, and Impact on Lipid Bilayers by Gładkowski, Witold, Chojnacka, Anna, Włoch, Aleksandra, Pruchnik, Hanna, Grudniewska, Aleksandra, Dunal, Anna, Dudek, Anita, Maciejewska, Gabriela, Rudzińska, Magdalena

“…The main aim of research was synthesis and spectroscopic characterization of new conjugates in which stigmasterol was linked via carbonate or succinyl linker…”
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Comparative Studies on the Susceptibility of (R)-2,3-Dipalmitoyloxypropylphosphonocholine (DPPnC) and Its Phospholipid Analogues to the Hydrolysis or Ethanolysis Catalyzed by Selected Lipases and Phospholipases by Paweł Mituła, Czesław Wawrzeńczyk, Witold Gładkowski

“…Susceptibility of soybean phosphatidylcholine, 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) and its phosphono analogue…”
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Microbial Asymmetric Functionalization of β-Cyclocitral-Derived Tetramethyl-Substituted γ-Lactone by Mazur, Marcelina, Gładkowski, Witold, Pawlak, Aleksandra, Obmińska-Mrukowicz, Bożena, Maciejewska, Gabriela, Wawrzeńczyk, Czesław

“…Searching for the new anticancer compounds we prepared three new β-cyclocitral-derived hydroxyl-γ-lactones by microbial hydroxylation of…”
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Microbial transformations of chalcones to produce food sweetener derivatives by Janeczko, Tomasz, Gładkowski, Witold, Kostrzewa-Susłow, Edyta

“…•As a biocatalyst we employed the strains which are commonly used in food industry.•Found an effective way to obtain dihydrochalcones (sweet taste).•Tested…”
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