Search Results - "Günthard, H."

Chemsex drugs on the rise: a longitudinal analysis of the Swiss HIV Cohort Study from 2007 to 2017 by Hampel, B, Kusejko, K, Kouyos, RD, Böni, J, Flepp, M, Stöckle, M, Conen, A, Béguelin, C, Künzler‐Heule, P, Nicca, D, Schmidt, AJ, Nguyen, H, Delaloye, J, Rougemont, M, Bernasconi, E, Rauch, A, Günthard, HF, Braun, DL, Fehr, J, Anagnostopoulos, A., Battegay, M., Bucher, H. C., Calmy, A., Cavassini, M., Ciuffi, A., Dollenmaier, G., Egger, M., Elzi, L., Fellay, J., Furrer, H., Fux, C. A., Haerry, D., Hasse, B., Hirsch, H. H., Hoffmann, M., Hösli, I., Huber, M., Kahlert, C., Kaiser, L., Keiser, O., Klimkait, T., Kovari, H., Ledergerber, B., Martinetti, G., Martinez de Tejada, B., Marzolini, C., Metzner, K. J., Müller, N., Paioni, P., Pantaleo, G., Perreau, M., Rudin, C., Scherrer, A. U., Schmid, P., Speck, R., Tarr, P., Trkola, A., Vernazza, P., Wandeler, G., Weber, R., Yerly, S.

“…Objectives Chemsex refers to the use of sex‐enhancing drugs among men who have sex with men (MSM) in combination with specific sexual and social behaviours…”
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Time Trends in Causes of Death in People With HIV: Insights From the Swiss HIV Cohort Study by Weber, M S R, Duran Ramirez, J J, Hentzien, M, Cavassini, M, Bernasconi, E, Hofmann, E, Furrer, H, Kovari, H, Stöckle, M, Schmid, P, Haerry, D, Braun, D L, Günthard, H F, Kusejko, K

“…Abstract Background Advancements in access to antiretroviral therapy (ART) and human immunodeficiency virus (HIV) care have led to a decline in AIDS-related…”
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Effective T-Cell Responses Select Human Immunodeficiency Virus Mutants and Slow Disease Progression by Frater, A J, Brown, H, Oxenius, A, Günthard, H F, Hirschel, B, Robinson, N, Leslie, A J, Payne, R, Crawford, H, Prendergast, A, Brander, C, Kiepiela, P, Walker, B D, Goulder, P J R, McLean, A, Phillips, R E

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Population pharmacokinetics of dolutegravir: influence of drug–drug interactions in a real-life setting by Barcelo, Catalina, Aouri, Manel, Courlet, Perrine, Guidi, Monia, Braun, Dominique L, Günthard, Huldrych F, Piso, Rein J, Cavassini, Matthias, Buclin, Thierry, Decosterd, Laurent A, Csajka, Chantal

“…Abstract Objectives Dolutegravir is widely prescribed owing to its potent antiviral activity, high genetic barrier and good tolerability. The aim of this study…”
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Analysis of inappropriate prescribing in elderly patients of the Swiss HIV Cohort Study reveals gender inequity by Livio, Françoise, Deutschmann, Elisabeth, Moffa, Giusi, Rrustemi, Flamur, Stader, Felix, Elzi, Luigia, Braun, Dominique L, Calmy, Alexandra, Hachfeld, Anna, Cavassini, Matthias, Tarr, Philip E, Wissel, Kerstin, Battegay, Manuel, Marzolini, Catia

“…Abstract Background The extent of inappropriate prescribing observed in geriatric medicine has not been thoroughly evaluated in people ageing with HIV. We…”
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Viral Diversity Based on Next-Generation Sequencing of HIV-1 Provides Precise Estimates of Infection Recency and Time Since Infection by Carlisle, Louisa A, Turk, Teja, Kusejko, Katharina, Metzner, Karin J, Leemann, Christine, Schenkel, Corinne D, Bachmann, Nadine, Posada, Susana, Beerenwinkel, Niko, Böni, Jürg, Yerly, Sabine, Klimkait, Thomas, Perreau, Matthieu, Braun, Dominique L, Rauch, Andri, Calmy, Alexandra, Cavassini, Matthias, Battegay, Manuel, Vernazza, Pietro, Bernasconi, Enos, Günthard, Huldrych F, Kouyos, Roger D

“…Human immunodeficiency virus type 1 (HIV-1) genetic diversity increases over the course of infection and can be used to infer the time since infection and,…”
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Decreasing Incidence and Determinants of Bacterial Pneumonia in People With HIV: The Swiss HIV Cohort Study by Balakrishna, Suraj, Wolfensberger, Aline, Kachalov, Viacheslav, Roth, Jan A, Kusejko, Katharina, Scherrer, Alexandra U, Furrer, Hansjakob, Hauser, Christoph, Calmy, Alexandra, Cavassini, Matthias, Schmid, Patrick, Bernasconi, Enos, Battegay, Manuel, Günthard, Huldrych F, Kouyos, Roger D

“…Abstract Background Bacterial pneumonia is a leading reason for hospitalization among people with HIV (PWH); however, evidence regarding its drivers in the era…”
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Antiretroviral Drugs Associated With Subclinical Coronary Artery Disease in the Swiss Human Immunodeficiency Virus Cohort Study by Kovari, Helen, Calmy, Alexandra, Doco-Lecompte, Thanh, Nkoulou, René, Marzel, Alex, Weber, Rainer, Kaufmann, Philipp A, Buechel, Ronny R, Ledergerber, Bruno, Tarr, Philip E

“…Abstract Background Coronary artery disease (CAD) events have been associated with certain antiretroviral therapy (ART) agents. In contrast, the influence of…”
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Changing Trends in International Versus Domestic HCV Transmission in HIV-Positive Men Who Have Sex With Men: A Perspective for the Direct-Acting Antiviral Scale-Up Era by Salazar-Vizcaya, Luisa, Kouyos, Roger D, Metzner, Karin J, Caraballo Cortes, Kamila, Böni, Jürg, Shah, Cyril, Fehr, Jan, Braun, Dominique L, Bernasconi, Enos, Mbunkah, Herbert A, Hoffmann, Matthias, Labhardt, Niklaus, Cavassini, Matthias, Rougemont, Mathieu, Günthard, Huldrych F, Keiser, Olivia, Rauch, Andri

“…Abstract Background Scale-up of direct-acting antiviral therapy is expected to abate hepatitis C virus (HCV) incidence among human immunodeficiency virus…”
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Using longitudinally sampled viral nucleotide sequences to characterize the drivers of HIV‐1 transmission by Reichmuth, ML, Chaudron, SE, Bachmann, N, Nguyen, H, Böni, J, Metzner, KJ, Perreau, M, Klimkait, T, Yerly, S, Hirsch, HH, Hauser, C, Ramette, A, Vernazza, P, Cavassini, M, Bernasconi, E, Günthard, HF, Kusejko, K, Kouyos, RD

“…Objectives Understanding the drivers of HIV‐1 transmission is of importance for curbing the ongoing epidemic. Phylogenetic methods based on single viral…”
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Emergence of Drug Resistance in the Swiss HIV Cohort Study Under Potent Antiretroviral Therapy Is Observed in Socially Disadvantaged Patients by Abela, Irene A, Scherrer, Alexandra U, Böni, Jürg, Yerly, Sabine, Klimkait, Thomas, Perreau, Matthieu, Hirsch, Hans H, Furrer, Hansjakob, Calmy, Alexandra, Schmid, Patrick, Cavassini, Matthias, Bernasconi, Enos, Günthard, Huldrych F

“…Abstract Background The rate of acquired human immunodeficiency virus type 1 (HIV-1) drug resistance (ADR) has fallen dramatically since introduction of…”
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Quantifying the drivers of HIV transmission and prevention in men who have sex with men: a population model‐based analysis in Switzerland by Kusejko, K, Marzel, A, Hampel, B, Bachmann, N, Nguyen, H, Fehr, J, Braun, DL, Battegay, M, Bernasconi, E, Calmy, A, Cavassini, M, Hoffmann, M, Böni, J, Yerly, S, Klimkait, T, Perreau, M, Rauch, A, Günthard, HF, Kouyos, RD

“…Objectives Despite the huge success of antiretroviral therapy (ART), there is an ongoing HIV epidemic among men who have sex with men (MSM) in resource‐rich…”
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Contribution of APOBEC3G/F activity to the development of low-abundance drug-resistant human immunodeficiency virus type 1 variants by Noguera-Julian, M., Cozzi-Lepri, A., Di Giallonardo, F., Schuurman, R., Däumer, M., Aitken, S., Ceccherini-Silberstein, F., D'Arminio Monforte, A., Geretti, A.M., Booth, C.L., Kaiser, R., Michalik, C., Jansen, K., Masquelier, B., Bellecave, P., Kouyos, R.D., Castro, E., Furrer, H., Schultze, A., Günthard, H.F., Brun-Vezinet, F., Metzner, K.J., Paredes, R., Paredes, Roger, Metzner, Karin J., Cozzi-Lepri, Alessandro, Schuurman, Rob, Brun-Vezinet, Francoise, Günthard, Huldrych, Ceccherini-Silberstein, Francesca, Kaiser, Rolf, Geretti, Anna Maria, Brockmeyer, Norbert, Masquelier, Bernard

“…Plasma drug-resistant minority human immunodeficiency virus type 1 variants (DRMVs) increase the risk of virological failure to first-line non-nucleoside…”
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Polypharmacy, Drug-Drug Interactions, and Inappropriate Drugs: New Challenges in the Aging Population With HIV by Courlet, Perrine, Livio, Françoise, Guidi, Monia, Cavassini, Matthias, Battegay, Manuel, Stoeckle, Marcel, Buclin, Thierry, Alves Saldanha, Susana, Csajka, Chantal, Marzolini, Catia, Decosterd, Laurent

“…Antiretroviral therapy has transformed HIV infection from a deadly into a chronic condition. Aging people with HIV (PWH) are at higher risk of polypharmacy,…”
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In Vivo Profiling and Distribution of Known and Novel Phase I and Phase II Metabolites of Efavirenz in Plasma, Urine, and Cerebrospinal Fluid by Aouri, Manel, Barcelo, Catalina, Ternon, Béatrice, Cavassini, Matthias, Anagnostopoulos, Alexia, Yerly, Sabine, Hugues, Henry, Vernazza, Pietro, Günthard, Huldrych F, Buclin, Thierry, Telenti, Amalio, Rotger, Margalida, Decosterd, Laurent A

“…Efavirenz (EFV) is principally metabolized by CYP2B6 to 8-hydroxy-efavirenz (8OH-EFV) and to a lesser extent by CYP2A6 to 7-hydroxy-efavirenz (7OH-EFV). So…”
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Importance of routine viral load monitoring: higher levels of resistance at ART failure in Uganda and Lesotho compared with Switzerland by Bachmann, Nadine, von Braun, Amrei, Labhardt, Niklaus D, Kadelka, Claus, Günthard, Huldrych F, Sekaggya-Wiltshire, Christine, Castelnuovo, Barbara, Kambugu, Andrew, Lejone, Thabo I, Böni, Jürg, Yerly, Sabine, Perreau, Matthieu, Klimkait, Thomas, Kouyos, Roger D, Fehr, Jan

“…Abstract Objectives Emerging resistance to antiretroviral drugs may jeopardize the achievements of improved access to ART. We compared the prevalence of…”
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Why do sub‐Saharan Africans present late for HIV care in Switzerland? by Hachfeld, A, Darling, K, Calmy, A, Ledergerber, B, Weber, R, Battegay, M, Wissel, K, Di Benedetto, C, Fux, CA, Tarr, PE, Kouyos, R, Ruggia, LS, Furrer, HJ, Wandeler, G, Aubert, V., Battegay, M., Bernasconi, E., Böni, J., Braun, D. L., Bucher, H. C., Calmy, A., Cavassini, M., Ciuffi, A., Dollenmaier, G., Egger, M., Elzi, L., Fehr, J., Fellay, J., Furrer, H., Fux, C. A., Günthard, H. F., Haerry, D., Hasse, B., Hirsch, H. H., Hoffmann, M., Hösli, I., Kahlert, C., Kaiser, L., Keiser, O., Klimkait, T., Kouyos, R. D., Kovari, H., Ledergerber, B., Martinetti, G., Martinez de Tejada, B., Marzolini, C., Metzner, K. J., Müller, N., Nicca, D., Pantaleo, G., Paioni, P., Rauch, A., Rudin, C., Scherrer, A. U., Schmid, P., Speck, R., Stöckle, M., Tarr, P., Trkola, A., Vernazza, P., Wandeler, G., Weber, R., Yerly, S.

“…Objectives Late presentation (LP) to HIV care disproportionally affects individuals from sub‐Saharan Africa (SSA). We explored the reasons for late…”
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Rapid decline of anti‐hepatitis C virus (HCV) antibodies following early treatment of incident HCV infections in HIV‐infected men who have sex with men by Aebi‐Popp, K, Wandeler, G, Salazar‐Vizcaya, L, Metzner, K, Stöckle, M, Cavassini, M, Hoffmann, M, Lüthi, A, Suter, F, Bernasconi, E, Fehr, J, Furrer, H, Rauch, A, Aubert, V, Battegay, M, Böni, J, Braun, D. L, Bucher, H. C, Calmy, A, Ciuffi, A, Dollenmaier, G, Egger, M, Elzi, L, Fellay, J, Fux, C. A, Günthard, H. F, Haerry, D, Hasse, B, Hirsch, H. H, Hösli, I, Kahlert, C, Kaiser, L, Keiser, O, Klimkait, T, Kouyos, R. D, Kovari, H, Ledergerber, B, Martinetti, G, Martinez de Tejada, B, Marzolini, C, Müller, N, Nicca, D, Pantaleo, G, Paioni, P, Rauch, A, Rudin, C, Scherrer, A. U, Schmid, P, Speck, R, Tarr, P, Trkola, A, Vernazza, P, Weber, R, Yerly, S

“…Objectives Following clearance of incident hepatitis C virus (HCV) infections, HCV antibody levels may decline, resulting in seroreversion. It is unclear to…”
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Virological outcome and management of persistent low-level viraemia in HIV-1-infected patients: 11 years of the Swiss HIV Cohort Study by Boillat-Blanco, Noémie, Darling, Katharine E A, Schoni-Affolter, Franziska, Vuichard, Danielle, Rougemont, Mathieu, Fulchini, Rosamaria, Bernasconi, Enos, Aouri, Manel, Clerc, Olivier, Furrer, Hansjakob, Günthard, Huldrych F, Cavassini, Matthias

“…Management of persistent low-level viraemia (pLLV) in patients on combined antiretroviral therapy (cART) with previously undetectable HIV viral loads (VLs) is…”
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Immunophenotypic characterization of TCR γδ T cells and MAIT cells in HIV-infected individuals developing Hodgkin's lymphoma by Muller, Christina K S, Spagnuolo, Julian, Audigé, Annette, Chancellor, Andrew, Russenberger, Doris, Scherrer, Alexandra U, Hoffmann, Matthias, Kouyos, Roger, Battegay, Manuel, De Libero, Gennaro, Speck, Roberto F

“…Despite successful combined antiretroviral therapy (cART), the risk of non-AIDS defining cancers (NADCs) remains higher for HIV-infected individuals than the…”
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