Search Results - "Gül, Özhan"

Investigation of the toxicity of bismuth oxide nanoparticles in various cell lines by Abudayyak, Mahmoud, Öztaş, Ezgi, Arici, Merve, Özhan, Gül

“…Nanoparticles have been drawn attention in various fields ranging from medicine to industry because of their physicochemical properties and functions, which…”
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Nickel oxide nanoparticles are highly toxic to SH-SY5Y neuronal cells by Abudayyak, Mahmoud, Guzel, Elif, Özhan, Gül

“…Nickel oxide nanoparticles (NiO-NPs) are used in many industrial sectors including printing inks, ceramics and catalysts, and electrical and electronics…”
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Reproductive effects of subchronic exposure to acetamiprid in male rats by Arıcan, Emre Yağmur, Gökçeoğlu Kayalı, Damla, Ulus Karaca, Bahar, Boran, Tuğçe, Öztürk, Narin, Okyar, Alper, Ercan, Feriha, Özhan, Gül

“…Acetamiprid, a selective agonist of nicotinic acetylcholine recetors, is one of the most widely used neonicotinoids. There is limited data about toxicity of…”
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Assessment of perfluorooctanoic acid toxicity in pancreatic cells by Abudayyak, Mahmoud, Öztaş, Ezgi, Özhan, Gül

“…Perfluorooctanoic acid (PFOA) was classified as a possible carcinogen for humans (Group 2B). The in vivo studies have reported that PFOA might lead to hepatic,…”
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Inflammation and oxidative stress are key mediators in AKB48-induced neurotoxicity in vitro by Oztas, Ezgi, Abudayyak, Mahmoud, Celiksoz, Muzeyyen, Özhan, Gül

“…Synthetic cannabinoids were introduced into market in early 2000s; since these “legal highs” are dramatically popular among youth, it becomes a deadly problem…”
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Ripretinib induced skeletal muscle toxicity through mitochondrial impairment in C2C12 myotubes by Boran, Tugce, Zengin, Ozge Sultan, Seker, Zehra, Akyildiz, Aysenur Gunaydin, Oztas, Ezgi, Özhan, Gül

“…Ripretinib is a multikinase inhibitor drug approved in 2020 by the FDA and in 2021 by EMA for use in the treatment of advanced gastrointestinal stromal tumors…”
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Cupric Oxide Nanoparticles Induce Cellular Toxicity in Liver and Intestine Cell Lines by Abudayyak, Mahmoud, Guzel, Elif, Özhan, Gül

“…Purpose: The wide application of cupric oxide nanoparticles (copper (II) oxide, CuO-NPs) in various fields has increased exposure to the kind of active…”
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The cyclin-dependent kinase inhibitor abemaciclib-induced hepatotoxicity: Insight on the molecular mechanisms in HepG2/THP-1 co-culture model by Boran, Tugce, Zengin, Ozge Sultan, Seker, Zehra, Gunaydin Akyildiz, Aysenur, Oztas, Ezgi, Özhan, Gül

“…Drug-induced liver injury (DILI) is one of the widespread causes of liver injury and immune system plays important role. Abemaciclib (ABE) is a…”
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Nickel Oxide Nanoparticles Induce Oxidative DNA Damage and Apoptosis in Kidney Cell Line (NRK-52E) by Abudayyak, Mahmoud, Guzel, Elif, Özhan, Gül

“…Increasing use of nickel oxide (NiO) nanoparticles in different applications results in high occupational and environmental exposure to them. However, the…”
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CYP2C9, CYPC19 and CYP2D6 gene profiles and gene susceptibility to drug response and toxicity in Turkish population by Arici, Merve, Özhan, Gül

“…Pharmacogenetics is a vast field covering drug discovery research, the genetic basis of pharmacokinetics and dynamics, genetic testing and clinical management…”
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In vitro evaluation of cobalt oxide nanoparticle-induced toxicity by Abudayyak, Mahmoud, Gurkaynak, Tuba Altincekic, Özhan, Gül

“…Cobalt oxide (Co3O4) nanoparticles have applications in nanomedicine and nanotechnology; therefore, any possible adverse effects require thorough…”
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Acetamiprid-induced Cyto- and Genotoxicity in the AR42J Pancreatic Cell Line by Kara, Mehtap, ÖztaŞ, Ezgi, Özhan, Gül

“…Neonicotinoid insecticides, 30% of insecticides marketed worldwide, have selective toxicity on insects through α4p2 nicotinic acetylcholine receptors. Although…”
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In Vitro Toxicological Assessment of Cobalt Ferrite Nanoparticles in Several Mammalian Cell Types by Abudayyak, Mahmoud, Altincekic Gurkaynak, Tuba, Özhan, Gül

“…Nanoparticles have been widely used in various fields due to the superior physicochemical properties and functions. As a result, human exposure to…”
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Cytotoxic, Genotoxic, and Apoptotic Effects of Nickel Oxide Nanoparticles in Intestinal Epithelial Cells by Abudayyak, Mahmoud, GÜzel, Elif, Özhan, Gül

“…The superior properties of nickel oxide-nanoparticles (NiO-NPs) have led to their wide use in various fields. However, there is little comprehensive knowledge…”
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In Vitro Toxicological Assessment of Magnesium Oxide Nanoparticle Exposure in Several Mammalian Cell Types by Mahmoud, Abudayyak, Ezgi, Öztaş, Merve, Arici, Özhan, Gül

“…Worldwide researchers have rising concerns about magnesium-based materials, especially magnesium oxide (MgO) nanaoparticles, due to increasing usage as…”
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UR-144, synthetic cannabinoid receptor agonist, induced cardiomyoblast toxicity mechanism comprises cytoplasmic Ca2+ and DAPK1 related autophagy and necrosis by Akar, Muzeyyen, Ercin, Merve, Boran, Tugce, Gezginci-Oktayoglu, Selda, Özhan, Gül

“…UR-144, a cannabinoid receptor agonist, is widely used alone or in combination with other synthetic cannabinoids (SCs) all over the world. At overdose,…”
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The Role of Endoplasmic Reticulum Stress in Cell Injury Induced by Methimazole on Pancreatic Cells by Yazıcı, Özge, Kara, Mehtap, Boran, Tuğçe, Ozhan, Gul

“…Purpose: Methimazole is an anti-thyroid agent, especially as main therapy option for Graves’ disease in children and adults. Drug induced pancreatitis is one…”
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Zoledronic acid‐induced oxidative damage and endoplasmic reticulum stress‐mediated apoptosis in human embryonic kidney (HEK‐293) cells by Kara, Mehtap, Boran, Tuğçe, Öztaş, Ezgi, Jannuzzi, Ayse Tarbin, Özden, Sibel, Özhan, Gül

“…Zoledronic acid, a nitrogen‐containing bisphosphonate drug, is used for the treatment of osteoporosis, Paget's disease of bone, and tumor‐induced osteolysis…”
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The genetic profiles of CYP1A1, CYP1A2 and CYP2E1 enzymes as susceptibility factor in xenobiotic toxicity in Turkish population by Arici, Merve, Özhan, Gül

“…Evaluation and sequencing of heritable alterations in the human genome and the large-scale identification of gene polymorphism for understanding the genetic…”
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Indole-based hydrazide-hydrazones and 4-thiazolidinones: synthesis and evaluation as antitubercular and anticancer agents by Cihan-Üstündağ, Gökçe, Şatana, Dilek, Özhan, Gül, Çapan, Gültaze

“…A new series of indolylhydrazones (6) and indole-based 4-thiazolidinones (7, 8) have been designed, synthesized and screened for in vitro antitubercular…”
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