RECURRENT ARTERIAL THROMBOSIS IN A CHILD: Primary Antiphospholipid Antibody Syndrome

Antiphospholipid antibody syndrome (APS) is characterized by the association of recurrent arterial or veneous thrombosis or recurrent fetal wasteage and the presence of circulating antiphospholipid antibodies, detected as anticardiolipin antibodies or lupus anticoagulant. The authors report an 8-yea...

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Bibliographic Details
Published in:	Pediatric hematology and oncology Vol. 19; no. 1; pp. 59 - 66
Main Authors:	Uysal, Zümrüt, Do u, Figen, Kürekçi, A. Emin, Çulha, Vildan Ko an, Deda, Gülhis, Ekim, Mesiha, Akar, Nejat, Ertem, Mehmet, Ikincio ullarí, Aydan, Babacan, Emel, Gözda oglu, Sevgi
Format:	Journal Article
Language:	English
Published:	Philadelphia, PA Informa UK Ltd 2002 Taylor & Francis
Subjects:	Antibodies, Anticardiolipin - blood Antiphospholipid Antibody Syndrome Antiphospholipid Syndrome - complications Antiphospholipid Syndrome - diagnosis Antiphospholipid Syndrome - immunology Arterial Thrombosis Biological and medical sciences Child Children Diagnosis, Differential Fatal Outcome Female Hematologic and hematopoietic diseases Humans Livedo Medical sciences Platelet diseases and coagulopathies Recurrence Reticularis Retinal Artery Occlusion - diagnosis Retinal Artery Occlusion - etiology Retinal Artery Occlusion - immunology Skin Diseases, Vascular - diagnosis Skin Diseases, Vascular - etiology Skin Diseases, Vascular - immunology Skin Diseases, Vascular - pathology Sneddon Syndrome Tropical medicine Asia Turkey Skin disease Cardiovascular disease Autoimmune disease Retina Hemopathy Livedo reticularis Arterial disease Vascular disease Ischemia Evolution Female Child Cerebrovascular disease Human Immunopathology Nervous system diseases Antiphospholipid antibody syndrome Thrombosis Artery Cerebral disorder Case study Symptomatology Eye disease Platelet Central nervous system disease Capillary vessel disease Brain (vertebrata)
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Summary:	Antiphospholipid antibody syndrome (APS) is characterized by the association of recurrent arterial or veneous thrombosis or recurrent fetal wasteage and the presence of circulating antiphospholipid antibodies, detected as anticardiolipin antibodies or lupus anticoagulant. The authors report an 8-year-old girl, who presented with central retinal artery occlusion and livedo reticularis and was diagnosed as APS. Despite the proper anticoagulant treatment she had several cerebral ischemic events a nd died 29 months after thediagnosis. A larger number of pediatric case investigations will be required for better understanding and treating this rare thrombotic disorder.
Bibliography:	ObjectType-Case Study-2 SourceType-Scholarly Journals-1 ObjectType-Feature-4 content type line 23 ObjectType-Report-1 ObjectType-Article-3
ISSN:	0888-0018 1521-0669
DOI:	10.1080/088800102753356202