Search Results - "Görigk, Sarah"
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E96V Mutation in the Kdelr3 Gene Is Associated with Type 2 Diabetes Susceptibility in Obese NZO Mice
Published in International journal of molecular sciences (03-01-2023)“…Type 2 diabetes (T2D) represents a multifactorial metabolic disease with a strong genetic predisposition. Despite elaborate efforts in identifying the genetic…”
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Nudix hydrolase NUDT19 regulates mitochondrial function and ATP production in murine hepatocytes
Published in Biochimica et biophysica acta. Molecular and cell biology of lipids (01-06-2022)“…Changes in intracellular CoA levels are known to contribute to the development of non-alcoholic fatty liver disease (NAFLD) in type 2 diabetes (T2D) in human…”
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Comparative genomic analyses of multiple backcross mouse populations suggest SGCG as a novel potential obesity-modifier gene
Published in Human molecular genetics (01-12-2022)“…To nominate novel disease genes for obesity and type 2 diabetes (T2D), we recently generated two mouse backcross populations of the T2D-susceptible New Zealand…”
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