Search Results - "Görgişen, Gökhan"

Relationship between MTHFR Gene Polymorphisms and Gastrointestinal Tumors Development: Perspective from Eastern Part of Turkey by Öksüz, Ersoy, Görgişen, Gökhan, Oto, Gökhan, Özdemir, Hülya, Aras, Abbas, Öksüz, Murat, Gülaçar, İsmail Musab, Demirkol, Muhammet Hamdi

“…Gastric and esophageal cancers are 2 of the most prevalent cancer types worldwide. Polymorphisms in the genes that code the methylenetetrahydrofolate reductase…”
Get full text

Overexpression of Insulin Receptor Substrate 1 (IRS1) Promotes Radioresistance In A172 Glioblastoma Cell Line by Görgişen, Gökhan, Çakır, Tahir, Ateş, Can, Gülaçar, İsmail Musab, Yaren, Zafer

“…Insulin receptor substrate 1 (IRS1) is the main adaptor molecule in insulin and insulin like growth factor signaling. Increased level of expression of IRS1 and…”
Get full text

Diabetıc Cardiomyopathy And G Protein by Behram Kandemir, Yasemin, Güntekin, Ünal, Aydın, Çiğdem, Görgişen, Gökhan

“…Diabetes mellitus (DM) is one of the most important disease in the modern society and represents not only a medical but also social problem. Cardiovascular…”
Get full text

Association of insulin-like growth factor binding protein-7 promoter methylation with esophageal cancer in peripheral blood by Kaya, Zehra, Almalı, Necat, Sahin, Elif Sena, Duran, Seren, Görgisen, Gökhan, Ates, Can

“…Background The insulin-like growth factor (IGF) signaling pathway has an important role in many cancers, including esophageal cancer (EC). IGF-binding protein…”
Get full text

Effect of Acetaminophen on Viability of HeLa Cells by Görgişen, Gökhan, Gülaçar, İsmail Musab, Öksüz, Ersoy

“…Acetaminophen is a widely used analgesic to release pain and reduce fever. Overdose medication could lead to serious medical conditions such as hepatotoxicity…”
Get full text

Insulin receptor substrate 1 overexpression promotes survival of glioblastoma cells through AKT1 activation by Gorgisen, Gokhan, Yaren, Zafer

“…Glioblastoma multiforme (GBM) is the most common and malignant type of central nervous system tumours in adults. Strict regulation of glucose homeostasis has a…”
Get full text

Preclinical Experimental Applications of miRNA Loaded BMSC Extracellular Vesicles by Cetin, Zafer, Saygili, Eyup I, Görgisen, Gokhan, Sokullu, Emel

“…Bone marrow mesenchymal stem cells have been investigated for many years, especially for tissue regeneration, and have inherent limitations. One of the rapidly…”
Get more information

The Role of Insulin Receptor Substrate Proteins in Bronchopulmonary Dysplasia and Asthma: New Potential Perspectives by Gorgisen, Gokhan, Aydin, Malik, Mboma, Olivier, Gökyildirim, Mira Y., Chao, Cho-Ming

“…Insulin receptor substrates (IRSs) are proteins that are involved in signaling through the insulin receptor (IR) and insulin-like growth factor (IGFR). They…”
Get full text

Abstract 3166: Clinopathologic correlation with the LCM based instability profiles for the mitochondrial microsatellite regions in the benign to metastatic transitions of surface epithelium ovarian tumor subtypes by Alper, Ozgul, Erdogan, Gulgun, Pestereli, Elif, Simsek, Tayup, Caliskan, Mualla O., Gulkesen, Hakan, Demir, Durkadin, Görgişen, Gökhan, Karaveli, Seyda, Lüleci, Güven

“…Abstract Background: Up to date, genomic and microgenomic changes have been identified in nuclear genome whereas, there is no available data about the…”
Get full text

Identification of novel mutations of Insulin Receptor Substrate 1 (IRS1) in tumor samples of non-small cell lung cancer (NSCLC): Implications for aberrant insulin signaling in development of cancer by Gorgisen, Gokhan, Hapil, Fatma Zehra, Yilmaz, Ozlem, Cetin, Zafer, Pehlivanoglu, Suray, Ozbudak, Irem Hicran, Erdogan, Abdullah, Ozes, Osman Nidai

“…Lung cancer is the leading cause of cancer-related death, and NSCLC constitutes nearly 85%-90% of all cases. The IRS proteins function as adaptors and transmit…”
Get full text

Role of Sedative-Hypnotic Agents in Neurodegeneration: Effects of Midazolam and Thiopental on Apoptosis and Oxidative Stress Expression in Neonatal and Adult Rat Brains by Soyalp, Celaleddin, Oksuz, Ersoy, Gorgisen, Gokhan, Gulacar, Ismail Musab, Yasar, Semih, Tuncdemir, Yunus Emre, Delen, Leman Acun

“…To investigate the effects of midazolam (MDZ) and thiopental on neonatal and adult rat brains. The study included adult and 7-day-old rats that were…”
Get full text

The Molecular Prevalence of Blastocystis spp. in Patients with Diarrhea

Get full text

The relationship between Fc epsilon receptor-1α and β ( FCER1A and FCER1B ) gene polymorphisms in patients with chronic urticaria using omalizumab by Savas, Hulya, Ozkol, Hatice Uce, Gorgisen, Gokhan, Özkol, Halil, Ates, Can, Metin, Ahmet, Özdemir, İlknur Yorgun

“…Chronic urticaria requires well-defined treatment strategies in order to achieve a maximum treatment response and maintain the quality of life. Since 2014,…”
Get full text

The ERK5/NF-κB signaling pathway targets endometrial cancer proliferation and survival by Diéguez-Martínez, Nora, Espinosa-Gil, Sergio, Yoldi, Guillermo, Megías-Roda, Elisabet, Bolinaga-Ayala, Idoia, Viñas-Casas, Maria, Gorgisen, Gokhan, Domingo-Ortí, Inés, Pérez-Montoyo, Héctor, Bayascas, Jose R., Colas, Eva, Dolcet, Xavier, Lizcano, Jose M.

“…Endometrial cancer (EC) is the most common type of gynecologic cancer in women of developed countries. Despite surgery combined with chemo-/radiotherapy…”
Get full text

The relationship between Fc epsilon receptor-1a and b (FCER1A and FCER1B) gene polymorphisms in patients with chronic urticaria using omalizumab by Savas, Hulya, Ozkol, Hatice, Gorgisen, Gokhan, Özkol, Halil, Ates, Can, Metin, Ahmet, Özdemir, İlknur Yorgun

Get full text

Antiproliferative and Apoptotic Role of Novel Synthesized Cu(II) Complex with 3-(3-(4-fluorophenyl)Triaz-1-en-1-yl) Benzenesulfonamide in Common Cancer Models by Tuluce, Yasin, Gorgisen, Gokhan, Gulacar, Ismail Musab, Koyuncu, Ismail, Durgun, Mustafa, Akocak, Suleyman, Ozkol, Halil, Kaya, Zehra

“…Chemotherapeutic treatment options are often ineffective due to the development of resistance in cancer cells. Therefore, developing new anti-cancer agents is…”
Get full text

Effect of Paracetamol in the Proliferation of Glioblastoma Cell Line: The Role of Apoptosis, COX-2 and Cyclin B Expressions by Oksuz, Ersoy, Gorgisen, Gokhan, Ozdemir, Hulya, Gulacar, Ismail Musab, Oto, Gokhan

“…To investigate the relationship between paracetamol and expression levels of cyclooxygenase-2, cyclin B, cell viability and apoptosis in glioblastoma cell…”
Get full text

Association of IRS1 Gly972Arg and IRS2 Gly1057Asp polymorphisms with gastric cancer in Turkish subjects by Gorgisen, Gokhan, Karatas, Ugur, Ates, Can, Oksuz, Murat, Gulacar, Ismail

“…Insulin receptor substrate (IRS) proteins are cytoplasmic adaptors that transmit the signal from the IR and insulin-like growth factor-1 receptor to effector…”
Get full text

Association of IRS1 Gly972Arg and IRS2 Gly 1057 Asp polymorphisms with gastric cancer in Turkish subjects by Gorgisen, Gokhan, Karatas, Ugur, Ates, Can, Oksuz, Murat, Gulacar, Ismail Musab

“…Insulin receptor substrate (IRS) proteins are cytoplasmic adaptors that transmit the signal from the IR and insulin-like growth factor-1 receptor to effector…”
Get full text

Evaluation of TP53 codon 72 polymorphism in esophageal cancer susceptibility in Eastern Anatolia Region of Turkey by Kaya, Zehra, Almali, Necat, Karan, Burak M, Gorgisen, Gokhan

“…The tumor suppressor TP53 gene plays a key role in the regulation of cell cycle. Polymorphisms in this gene have been associated with many cancers including…”
Get full text