Search Results - "Göke, Katrin"
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Novel strategies for the formulation and processing of poorly water-soluble drugs
Published in European journal of pharmaceutics and biopharmaceutics (01-05-2018)“…[Display omitted] Low aqueous solubility of active pharmaceutical ingredients presents a serious challenge in the development process of new drug products…”
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Heat Treatment of Poloxamer-Stabilized Triglyceride Nanodispersions: Effects and Underlying Mechanism
Published in Molecular pharmaceutics (06-08-2018)“…Lipid nanoemulsions are being investigated for the parenteral administration of poorly soluble drugs. A narrow particle size distribution in these formulations…”
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Control over Particle Size Distribution by Autoclaving Poloxamer-Stabilized Trimyristin Nanodispersions
Published in Molecular pharmaceutics (06-09-2016)“…Lipid nanoparticles are under investigation as delivery systems for poorly water-soluble drugs. The particle size in these dispersions strongly influences…”
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Drug solubility in lipid nanocarriers: Influence of lipid matrix and available interfacial area
Published in International journal of pharmaceutics (30-08-2017)“…[Display omitted] Amongst other strategies for the formulation of poorly water-soluble drugs, solubilization of these drugs in lipid-based formulations is a…”
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Parameters influencing the course of passive drug loading into lipid nanoemulsions
Published in European journal of pharmaceutics and biopharmaceutics (01-05-2018)“…[Display omitted] Passive drug loading can be used to effectively identify suitable colloidal lipid carrier systems for poorly water-soluble drugs. This method…”
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Carrier characteristics influence the kinetics of passive drug loading into lipid nanoemulsions
Published in European journal of pharmaceutics and biopharmaceutics (01-05-2018)“…[Display omitted] Passive loading as a novel screening approach is a material-saving tool for the efficient selection of a suitable colloidal lipid carrier…”
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Alkynyl gold(I) phosphane complexes: Evaluation of structure–activity-relationships for the phosphane ligands, effects on key signaling proteins and preliminary in-vivo studies with a nanoformulated complex
Published in Journal of inorganic biochemistry (01-07-2016)“…Gold alkynyl complexes with phosphane ligands of the type (alkynyl)Au(I)(phosphane) represent a group of bioorganometallics, which has only recently been…”
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