Search Results - "Górecki, L."

Tetroxime: reactivation potency - in vitro and in silico study by Kuca, K, Korabecny, J, Dolezal, R, Nepovimova, E, Soukup, O, Gorecki, L, Musilek, K

“…Acetylcholinesterase (AChE) reactivators (oximes) are generally used as treatment in cases of nerve agent poisoning. There is no single oxime applicable in…”
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P.760 Effects of novel cholinesterase inhibitors on mitochondrial respiration and MAO activity - in vitro study by Hroudová, J., Korábečný, J., Špilovská, K., Mezeiová, E., Górecki, L., Maliňák, D., Fišar, Z.

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A 7-methoxytacrine-4-pyridinealdoxime hybrid as a novel prophylactic agent with reactivation properties in organophosphate intoxication by Nepovimova, E, Korabecny, J, Dolezal, R, Nguyen, T D, Jun, D, Soukup, O, Pasdiorova, M, Jost, P, Muckova, L, Malinak, D, Gorecki, L, Musilek, K, Kuca, Kamil

“…Chemical warfare agents constitute an increasing threat to both military and civilian populations. Therefore, effective prophylactic approaches are urgently…”
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A 7-methoxytacrine-4-pyridinealdoxime hybrid as a novel prophylactic agent with reactivation properties in organophosphate intoxicationElectronic supplementary information (ESI) available: Experimental procedures and characterization of all compounds. See DOI: 10.1039/c6tx00130k by Nepovimova, E, Korabecny, J, Dolezal, R, Nguyen, T. D, Jun, D, Soukup, O, Pasdiorova, M, Jost, P, Muckova, L, Malinak, D, Gorecki, L, Musilek, K, Kuca, Kamil

“…Chemical warfare agents constitute an increasing threat to both military and civilian populations. Therefore, effective prophylactic approaches are urgently…”
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A 7-methoxytacrine–4-pyridinealdoxime hybrid as a novel prophylactic agent with reactivation properties in organophosphate intoxication† †Electronic supplementary information (ESI) available: Experimental procedures and characterization of all compounds. See DOI: 10.1039/c6tx00130k by Nepovimova, E., Korabecny, J., Dolezal, R., Nguyen, T. D., Jun, D., Soukup, O., Pasdiorova, M., Jost, P., Muckova, L., Malinak, D., Gorecki, L., Musilek, K., Kuca, Kamil

“…A novel hybrid able to protect organophosphate-inhibited AChE as well as to reactivate it. Chemical warfare agents constitute an increasing threat to both…”
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