Search Results - "Góngora, Rafael"
-
1
Comprehensive and systematic characterization of multi-functionalized cisplatin nano-conjugate: from the chemistry and proteomic biocompatibility to the animal model
Published in Journal of nanobiotechnology (20-07-2022)“…Abstract Background Nowadays, nanoparticles (NPs) have evolved as multifunctional systems combining different custom anchorages which opens a wide range of…”
Get full text
Journal Article -
2
Dynamic Intracellular Metabolic Cell Signaling Profiles During Ag-Dependent B-Cell Differentiation
Published in Frontiers in immunology (30-03-2021)“…Human B-cell differentiation has been extensively investigated on genomic and transcriptomic grounds; however, no studies have accomplished so far detailed…”
Get full text
Journal Article -
3
Etiologic Agent of an Epidemic of Cutaneous Leishmaniasis in Tolima, Colombia
Published in The American journal of tropical medicine and hygiene (01-02-2008)“…American cutaneous leishmaniasis (ACL) has been characterized as a zoonotic disease. However, peridomestic and domestic transmission have been recorded in at…”
Get full text
Journal Article -
4
Deregulation of selective autophagy during aging and pulmonary fibrosis: the role of TGFβ1
Published in Aging cell (01-10-2015)“…Summary Aging constitutes a significant risk factor for fibrosis, and idiopathic pulmonary fibrosis (IPF) is characteristically associated with advancing age…”
Get full text
Journal Article -
5
Sirtuin 3 Deregulation Promotes Pulmonary Fibrosis
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (01-05-2017)“…Oxidative stress leads to alveolar epithelial cell injury and fibroblast-myofibroblast differentiation (FMD), key events in the pathobiology of pulmonary…”
Get full text
Journal Article -
6
Diversity and interactions among triatomine bugs, their blood feeding sources, gut microbiota and Trypanosoma cruzi in the Sierra Nevada de Santa Marta in Colombia
Published in Scientific reports (10-06-2021)“…Chagas disease remains a major neglected disease in Colombia. We aimed to characterize Trypanosoma cruzi transmission networks in the Sierra Nevada de Santa…”
Get full text
Journal Article -
7
Single-Cell Proteomics: The Critical Role of Nanotechnology
Published in International journal of molecular sciences (16-06-2022)“…In single-cell analysis, biological variability can be attributed to individual cells, their specific state, and the ability to respond to external stimuli,…”
Get full text
Journal Article -
8
Crucial Parameters for Immunopeptidome Characterization: A Systematic Evaluation
Published in International journal of molecular sciences (03-09-2024)“…Immunopeptidomics is the area of knowledge focused on the study of peptides assembled in the major histocompatibility complex (MHC), or human leukocyte antigen…”
Get full text
Journal Article -
9
Interactions of Nanoparticles and Biosystems: Microenvironment of Nanoparticles and Biomolecules in Nanomedicine
Published in Nanomaterials (Basel, Switzerland) (24-09-2019)“…Nanotechnology is a multidisciplinary science covering matters involving the nanoscale level that is being developed for a great variety of applications…”
Get full text
Journal Article -
10
Autoimmune Responses in Oncology: Causes and Significance
Published in International journal of molecular sciences (01-08-2021)“…Specific anti-tumor immune responses have proven to be pivotal in shaping tumorigenesis and tumor progression in solid cancers. These responses can also be of…”
Get full text
Journal Article -
11
Translational research into frailty from bench to bedside: Salivary biomarkers for inflammaging
Published in Experimental gerontology (01-01-2023)“…Frailty is a complex physiological syndrome associated with adverse ageing and decreased physiological reserves. Frailty leads to cognitive and physical…”
Get full text
Journal Article -
12
Regulation of transforming growth factor-beta1 (TGF-β1)-induced pro-fibrotic activities by circadian clock gene BMAL1
Published in Respiratory research (12-01-2016)“…BMAL1 is a transcriptional activator of the molecular clock feedback network. Besides its role in generating circadian rhythms, it has also been shown to be…”
Get full text
Journal Article -
13
Restoring the Immunity in the Tumor Microenvironment: Insights into Immunogenic Cell Death in Onco-Therapies
Published in Cancers (05-06-2021)“…Immunogenic cell death (ICD) elicited by cancer therapy reshapes the tumor immune microenvironment. A long-term adaptative immune response can be initiated by…”
Get full text
Journal Article -
14
SARS-CoV-2 Infection Triggers Auto-Immune Response in ARDS
Published in Frontiers in immunology (28-01-2022)“…Acute respiratory distress syndrome (ARDS) is a severe pulmonary disease, which is one of the major complications in COVID-19 patients. Dysregulation of the…”
Get full text
Journal Article -
15
Parasitological Confirmation and Analysis of Leishmania Diversity in Asymptomatic and Subclinical Infection following Resolution of Cutaneous Leishmaniasis
Published in PLoS neglected tropical diseases (01-12-2015)“…The contribution of individuals with subclinical infection to the transmission and endemicity of cutaneous leishmaniasis (CL) is unknown. Immunological…”
Get full text
Journal Article -
16
Unravelling soluble immune checkpoints in chronic lymphocytic leukemia: Physiological immunomodulators or immune dysfunction
Published in Frontiers in immunology (28-09-2022)“…Chronic lymphocytic leukemia (CLL) is a lymphoid neoplasm characterized by the accumulation of mature B cells. The diagnosis is established by the detection of…”
Get full text
Journal Article -
17
Screening Phage-Display Antibody Libraries Using Protein Arrays
Published in Methods in molecular biology (Clifton, N.J.) (2018)“…Phage-display technology constitutes a powerful tool for the generation of specific antibodies against a predefined antigen. The main advantages of…”
Get more information
Journal Article -
18
Functional proteomic insights in B-cell chronic lymphocytic leukemia
Published in Expert review of proteomics (01-02-2017)“…B cell chronic lymphocytic leukemia (B-CLL) is a hematological malignancy considered as the most common leukemia in the Western world. The understanding of B…”
Get more information
Journal Article -
19
Deciphering Human Leukocyte Antigen Susceptibility Maps From Immunopeptidomics Characterization in Oncology and Infections
Published in Frontiers in cellular and infection microbiology (28-05-2021)“…Genetic variability across the three major histocompatibility complex (MHC) class I genes (human leukocyte antigen [HLA] A, B, and C) may affect susceptibility…”
Get full text
Journal Article -
20
Systematic Evaluation of Antigenic Stimulation in Chronic Lymphocytic Leukemia: Humoral Immunity as Biomarkers for Disease Evolution
Published in Cancers (31-01-2023)“…Chronic lymphocytic leukemia (CLL) is the most common leukemia in the Western world. Studies of CLL antibody reactivity have shown differential targets to…”
Get full text
Journal Article