Endocannabinoid/GABA interactions in the entopeduncular nucleus modulates alcohol intake in rats

Highlights ► The endocannabinoid system in the entopeduncular nucleus modulate alcohol intake. ► Endocannabinoids–GABA interaction in entopeduncular nucleus modulates alcohol intake. ► CB1R activation in the entopeduncular nucleus reduced alcohol intake in rats. ► CB1R inactivation in the entopedunc...

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Bibliographic Details
Published in:	Brain research bulletin Vol. 91; pp. 31 - 37
Main Authors:	Méndez-Díaz, Mónica, Caynas Rojas, Seraid, Gómez Armas, David, Ruiz-Contreras, Alejandra E, Aguilar-Roblero, Raúl, Prospéro-García, Oscar
Format:	Journal Article
Language:	English
Published:	United States Elsevier Inc 01-02-2013
Subjects:	Alcohol Drinking - metabolism Alcohol intake Alcoholism - metabolism Anandamide Animals Cannabinoid receptor 1 Endocannabinoids - metabolism Entopeduncular nucleus Entopeduncular Nucleus - drug effects Entopeduncular Nucleus - metabolism GABA Agonists - administration & dosage GABA Antagonists - administration & dosage GABAB receptor gamma-Aminobutyric Acid - metabolism Injections, Intraventricular Male Neurology Rats Rats, Wistar Receptor, Cannabinoid, CB1 - metabolism Synaptic Transmission - drug effects Synaptic Transmission - physiology Alcohol intake GABAB receptor Cannabinoid receptor 1 Anandamide Entopeduncular nucleus
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Summary:	Highlights ► The endocannabinoid system in the entopeduncular nucleus modulate alcohol intake. ► Endocannabinoids–GABA interaction in entopeduncular nucleus modulates alcohol intake. ► CB1R activation in the entopeduncular nucleus reduced alcohol intake in rats. ► CB1R inactivation in the entopeduncular nucleus increases alcohol intake in rats.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0361-9230 1873-2747
DOI:	10.1016/j.brainresbull.2012.11.010