Search Results - "Gómez‐Zamudio, Jaime"
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Altered Glycemic Control Associated With Polymorphisms in the SLC22A1 (OCT1) Gene in a Mexican Population With Type 2 Diabetes Mellitus Treated With Metformin: A Cohort Study
Published in Journal of clinical pharmacology (01-10-2019)“…The organic cation transporters OCT1 and OCT2 and the multidrug and toxin extrusion transporter MATE1, encoded by the SLC22A1, SLC22A2, and SLC47A1 genes,…”
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Genetic variants in SLC22A1 are related to serum lipid levels in Mexican women
Published in Lipids (01-03-2022)“…Dyslipidemia is the main risk factor for coronary artery disease and is characterized by alterations in concentrations of lipids, including low‐density…”
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3
Vascular endothelial function is improved by oral glycine treatment in aged rats
Published in Canadian journal of physiology and pharmacology (01-06-2015)“…Glycine has been used to reduce oxidative stress and proinflammatory mediators in some metabolic disorders; however, its effect on the vasculature has been…”
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Role of Perivascular Adipose Tissue in Aorta Reactivity from Obese and Hyperglycemic CD-1 Mice: New Insights into Perivascular Adipose Tissue
Published in Metabolic syndrome and related disorders (01-03-2023)“…Perivascular adipose tissue (PVAT) plays an essential role in cardiovascular homeostasis. However, during obesity and diabetes, its role in vascular tone…”
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SOD2 gene Val16Ala polymorphism is associated with macroalbuminuria in Mexican type 2 diabetes patients: a comparative study and meta-analysis
Published in BMC medical genetics (11-10-2013)“…Several studies in type 2 diabetes patients have shown significant associations between the SOD2 gene Val16Ala polymorphism and albuminuria, but this…”
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Analysis of Flavonoids Bioactivity for Cholestatic Liver Disease: Systematic Literature Search and Experimental Approaches
Published in Biomolecules (Basel, Switzerland) (14-03-2019)“…Flavonoids are naturally occurring compounds that show health benefits on the liver. However, there is little investigation about identification and evaluation…”
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Effect of bis-1,4-Dihydropyridine in the Kidney of Diabetic Rats
Published in Journal of Pharmacological Sciences (2013)“…The in vivo effectiveness of 4-dihydropyridine (bis-1,4-DHP), a new calcium-channel blocker, as a nephroprotector in isolated perfused kidney was evaluated by…”
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Antidiabetic, antihyperlipidemic and anti-inflammatory effects of tilianin in streptozotocin-nicotinamide diabetic rats
Published in Biomedicine & pharmacotherapy (01-10-2016)“…Graphical abstract…”
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Expression of obesity- and type-2 diabetes-associated genes in omental adipose tissue of individuals with obesity
Published in Gene (20-03-2022)“…•Gene expression in VAT of obese (OB) patients depends on T2D diagnostics.•Expression of HP in VAT correlates positively with cholesterol levels in…”
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Assessing the effects of 35 European‐derived BMI‐associated SNPs in Mexican children
Published in Obesity (Silver Spring, Md.) (01-09-2016)“…Objective The prevalence of obesity in Mexico has increased at an alarming rate in both adults and children. This study was undertaken to test in Mexican…”
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PPARα/γ, adiponectin, and GLUT4 overexpression induced by moronic acid methyl ester influenced glucose and triglyceride levels of experimental diabetic mice
Published in Canadian journal of physiology and pharmacology (01-04-2022)“…The current study aimed to determine the antidiabetic and antidyslipidemic activities of moronic acid methyl ester (1) (compound ) by in vivo, in vitro, in…”
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Antidiabetic, antidyslipidemic and toxicity profile of ENV-2: A potent pyrazole derivative against diabetes and related diseases
Published in European journal of pharmacology (15-05-2017)“…Diabetes is a major health problem and a predisposition factor for further degenerative complications and, therefore, novel therapies are urgently needed…”
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Pancreatic β-Cell Apoptosis in Normoglycemic Rats is Due to Mitochondrial Translocation of p53-Induced by the Consumption of Sugar-Sweetened Beverages
Published in Cell biochemistry and biophysics (01-09-2023)“…Overstimulation of pancreatic β-cells can lead to dysfunction and death, prior to the clinical manifestations of type 2 diabetes (T2D). The excessive…”
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Association of rs2000999 in the haptoglobin gene with total cholesterol, HDL-C, and LDL-C levels in Mexican type 2 diabetes patients
Published in Medicine (Baltimore) (01-09-2019)“…Recently, studies have shown significant association between the rs2000999 polymorphism in the haptoglobin-encoding gene (HP) and low-density lipoprotein…”
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Participation of the IKK-α/β complex in the inhibition of the TNF-α/NF-κB pathway by glycine: Possible involvement of a membrane receptor specific to adipocytes
Published in Biomedicine & pharmacotherapy (01-06-2018)“…[Display omitted] Glycine modulates inflammatory processes mediated by macrophages and adipocytes through decreasing the secretion of TNF-α, IL-6, and leptin,…”
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High Thyroid-stimulating Hormone Levels Increase Proinflammatory and Cardiovascular Markers in Patients with Extreme Obesity
Published in Archives of medical research (01-08-2016)“…Background and Aims Obesity is an important health problem worldwide and many studies have suggested a relationship between obesity and thyroid function, with…”
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The rs1256031 of estrogen receptor β gene is associated with type 2 diabetes
Published in Diabetes & metabolic syndrome clinical research & reviews (01-09-2018)“…To determine the association between the rs1256031 polymorphism and risk of developing type 2 diabetes. Cases and controls study. 597 individuals with type 2…”
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Response: High Thyroid-stimulating Hormone Levels Increase Proinflammatory and Cardiovascular Markers in Patients with Extreme Obesity
Published in Archives of medical research (01-02-2017)Get full text
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Genetic markers of inflammation may not contribute to metabolic traits in Mexican children
Published in PeerJ (San Francisco, CA) (23-06-2016)“…Low-grade chronic inflammation is a common feature of obesity and its cardio-metabolic complications. However, little is known about a possible causal role of…”
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Level of expression of gene CTSL and its correlation with natural killer T-Cells in mexican pediatric patients with recent-onset type 1 diabetes
Published in Gaceta médica de México (01-10-2016)“…To compare the level of expression of the gene CTSL and its correlation with NKT cells in patients with recent-onset type 1 diabetes (T1D), their siblings, and…”
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